{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T08:39:19Z","timestamp":1778315959986,"version":"3.51.4"},"reference-count":56,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2019,10,18]],"date-time":"2019-10-18T00:00:00Z","timestamp":1571356800000},"content-version":"vor","delay-in-days":365,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100007188","name":"Uniformed Services University of the Health Sciences","doi-asserted-by":"publisher","award":["R072IC"],"award-info":[{"award-number":["R072IC"]}],"id":[{"id":"10.13039\/100007188","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["1ZIAHD000641"],"award-info":[{"award-number":["1ZIAHD000641"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000071","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000071","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006545","name":"National Institute on Minority Health and Health Disparities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006545","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000118","name":"Office of Behavioral and Social Sciences Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000118","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>Pediatric loss-of-control (LOC) eating is associated with, and predictive of, gains in adiposity and adverse metabolic outcomes. In addition, some preliminary data suggest that anxiety may exacerbate the relationship of LOC eating with weight and metabolic syndrome (MetS)-related measures. We therefore examined whether anxiety moderated the relationship between LOC eating and body mass index z (BMIz), adiposity, and MetS-related measures in youth.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A convenience sample of non-treatment-seeking boys and girls of varying weight strata were interviewed to determine the presence of LOC eating and completed a questionnaire assessing trait anxiety. BMIz and MetS-related measures (blood pressure, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, glucose, and insulin) were measured after an overnight fast. Adiposity was assessed by air displacement plethysmography or dual-energy x-ray absorptiometry. Analyses adjusted for age, sex, race, height, fat mass, and depressive symptoms, as appropriate.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>In all, 379 youths (13.0 \u00b1 2.8 years; 53% female; BMIz\u2009=\u20090.8 \u00b1 1.1; 22% with LOC eating) were studied. Anxiety was not significantly related to BMIz, adiposity, or MetS-related measures. However, anxiety and LOC eating interacted such that only among youth with LOC eating, anxiety was positively associated with fasting insulin (p = .02) and insulin resistance (p = .01). The interaction of anxiety and LOC eating was not significantly related to BMIz, adiposity, or any other MetS-related measure (ps = ns).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Only among non-treatment-seeking youth with LOC eating, anxiety may be associated with increased insulin secretion and insulin resistance. Longitudinal studies are required to confirm these findings and explore mechanisms for these relationships.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jpepsy\/jsy077","type":"journal-article","created":{"date-parts":[[2018,9,3]],"date-time":"2018-09-03T19:55:26Z","timestamp":1536004526000},"page":"220-228","source":"Crossref","is-referenced-by-count":21,"title":["Pediatric Loss-of-Control Eating and Anxiety in Relation to Components of Metabolic Syndrome"],"prefix":"10.1093","volume":"44","author":[{"given":"Meghan E","family":"Byrne","sequence":"first","affiliation":[{"name":"Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences (USUHS)"},{"name":"Section on Growth and Obesity, Program in Endocrinology, Metabolism and Genetics, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), DHHS"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marian","family":"Tanofsky-Kraff","sequence":"first","affiliation":[{"name":"Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences (USUHS)"},{"name":"Section on Growth and Obesity, Program in Endocrinology, Metabolism and Genetics, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), DHHS"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nichole R","family":"Kelly","sequence":"first","affiliation":[{"name":"Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences (USUHS)"},{"name":"Section on Growth and Obesity, Program in Endocrinology, Metabolism and Genetics, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), DHHS"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne Claire","family":"Grammer","sequence":"first","affiliation":[{"name":"Section on Growth and Obesity, Program in Endocrinology, Metabolism and Genetics, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), DHHS"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuela","family":"Jaramillo","sequence":"first","affiliation":[{"name":"Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences (USUHS)"},{"name":"Section on Growth and Obesity, Program in Endocrinology, Metabolism and Genetics, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), DHHS"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah J","family":"Mi","sequence":"first","affiliation":[{"name":"Section on Growth and Obesity, Program in Endocrinology, Metabolism and Genetics, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), DHHS"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monika M","family":"Stojek","sequence":"first","affiliation":[{"name":"Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences (USUHS)"},{"name":"Section on Growth and Obesity, Program in Endocrinology, Metabolism and Genetics, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), DHHS"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa M","family":"Shank","sequence":"first","affiliation":[{"name":"Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences (USUHS)"},{"name":"Section on Growth and Obesity, Program in Endocrinology, Metabolism and Genetics, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), DHHS"},{"name":"Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natasha L","family":"Burke","sequence":"first","affiliation":[{"name":"Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences (USUHS)"},{"name":"Section on Growth and Obesity, Program in Endocrinology, Metabolism and Genetics, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), DHHS"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omni","family":"Cassidy","sequence":"first","affiliation":[{"name":"Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences (USUHS)"},{"name":"Section on Growth and Obesity, Program in Endocrinology, Metabolism and Genetics, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), DHHS"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natasha A","family":"Schvey","sequence":"first","affiliation":[{"name":"Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences (USUHS)"},{"name":"Section on Growth and Obesity, Program in Endocrinology, Metabolism and Genetics, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), DHHS"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheila M","family":"Brady","sequence":"first","affiliation":[{"name":"Section on Growth and Obesity, Program in Endocrinology, Metabolism and Genetics, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), 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