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The present study examined symptom profiles of CD and ODD among youth with PHIV and whether profiles differed in terms of parent\u2013child and family correlates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Participants included 314 youth with PHIV, aged 6\u201317\u2009years (M\u2009=\u200912.88\u2009years, SD = 3.08; 51% male; 85% Black or Latinx), and their caregivers who were recruited from 29 clinics in the US involved in the International Maternal Pediatrics Adolescent AIDS Clinical Trials (IMPAACT) Group\u2019s P1055 study. Caregivers reported on youth CD and ODD symptoms, parent\u2013child interactions, and family environment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Latent class analysis indicated that a four-class model (i.e., moderate CD\/high ODD, high ODD, moderate ODD, low CD\/ODD) best fit the data. Ancillary analyses to validate these classes revealed differences for family cohesion and conflict; and child-centeredness, detachment, guilt-induced control, and consistency in parent\u2013child interactions. The low CD\/ODD class generally differed from other classes with additional differentiation between some higher risk profiles.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Findings suggest that homogeneous classes of CD\/ODD symptoms can be identified among youth with PHIV, and these profiles differ in terms of family processes, consistent with previous work among chronically ill youth.<\/jats:p><\/jats:sec>","DOI":"10.1093\/jpepsy\/jsz074","type":"journal-article","created":{"date-parts":[[2019,9,4]],"date-time":"2019-09-04T19:27:38Z","timestamp":1567625258000},"page":"72-80","source":"Crossref","is-referenced-by-count":3,"title":["Symptom Profiles of CD and ODD Among Youth With Perinatally Acquired HIV"],"prefix":"10.1093","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4293-9959","authenticated-orcid":false,"given":"Ijeoma","family":"Osigwe","sequence":"first","affiliation":[{"name":"Temple University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth D","family":"Gadow","sequence":"additional","affiliation":[{"name":"Stony Brook University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharon","family":"Nachman","sequence":"additional","affiliation":[{"name":"Stony Brook University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah A G","family":"Drabick","sequence":"additional","affiliation":[{"name":"Temple University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,10,10]]},"reference":[{"key":"2021013007550451100_jsz074-B1","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/BF02294359","article-title":"Factor analysis and AIC","volume":"52","author":"Akaike","year":"1987","journal-title":"Psychometrika"},{"key":"2021013007550451100_jsz074-B2","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1097\/00004583-199902000-00011","article-title":"Impaired but undiagnosed","volume":"38","author":"Angold","year":"1999","journal-title":"Journal of the American Academy of Child and Adolescent Psychiatry"},{"key":"2021013007550451100_jsz074-B3","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1093\/sw\/46.2.159","article-title":"Challenges of parenting for families living with HIV\/AIDS","volume":"46","author":"Antle","year":"2001","journal-title":"Social Work"},{"key":"2021013007550451100_jsz074-B4","author":"Asparaouhov","year":"2012"},{"key":"2021013007550451100_jsz074-B5","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1111\/j.1469-7610.2004.00265.x","article-title":"Do risk factors for problem behaviour act in a cumulative manner? 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