{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T05:05:22Z","timestamp":1771995922913,"version":"3.50.1"},"reference-count":37,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2019,10,31]],"date-time":"2019-10-31T00:00:00Z","timestamp":1572480000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Provide an overview of current research findings in pediatric central disorders of hypersomnolence (CDH) and propose a biopsychosocial model for clinical management, with a focus on interdisciplinary care and future directions for research and clinical practice.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Literature review drawing from pediatric and adult narcolepsy, as well as pediatric sleep and chronic pain research to develop an integrative biopsychosocial model for pediatric CDH.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Youth with CDH are vulnerable to impairments in academics, emotional, and behavioral functioning, activity engagement and quality of life (QOL). There is a complex interrelationship between neurobiological features of disease, treatment-related factors, and psychological, sleep-related, and contextual factors across development. Research is limited largely to adults and pediatric narcolepsy type 1 and the mechanisms and evolution of morbidity remain poorly understood.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In addition to first-line treatment (pharmacotherapy), routine screening of bio-behavioral and psychosocial functioning and QOL is needed to identify risk for compromised functioning warranting adjunctive interventions with behavioral health specialists.<\/jats:p><\/jats:sec>","DOI":"10.1093\/jpepsy\/jsz085","type":"journal-article","created":{"date-parts":[[2019,10,8]],"date-time":"2019-10-08T08:14:30Z","timestamp":1570522470000},"source":"Crossref","is-referenced-by-count":6,"title":["Topical Review: A Biopsychosocial Framework for Pediatric Narcolepsy and Idiopathic Hypersomnia"],"prefix":"10.1093","author":[{"given":"Danielle M","family":"Graef","sequence":"first","affiliation":[{"name":"Sleep Center, Divisions of Pulmonary Medicine and Behavioral Medicine\/Clinical Psychology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, OH"},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelly C","family":"Byars","sequence":"additional","affiliation":[{"name":"Sleep Center, Divisions of Pulmonary Medicine and Behavioral Medicine\/Clinical Psychology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, OH"},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Narong","family":"Simakajornboon","sequence":"additional","affiliation":[{"name":"Sleep Center, Divisions of Pulmonary Medicine and Behavioral Medicine\/Clinical Psychology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, OH"},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas J","family":"Dye","sequence":"additional","affiliation":[{"name":"Sleep Center, Divisions of Pulmonary Medicine and Behavioral Medicine\/Clinical Psychology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, OH"},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,10,31]]},"reference":[{"key":"2019103111093395500_jsz085-B1","volume-title":"International classification of sleep disorders, third edition (ICSD-3).","author":"American Academy of Sleep Medicine","year":"2014"},{"key":"2019103111093395500_jsz085-B2","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1093\/sleep\/33.11.1457","article-title":"Clinical and therapeutic aspects of childhood narcolepsy-cataplexy: A retrospective study of 51 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