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This report describes a rare cause of endocarditis in humans, Bartonella vinsonii, identified through next generation sequencing of plasma microbial cell-free DNA with confirmation of cardiac valve tissue infection through immunohistochemical staining and polymerase chain reaction.<\/jats:p>","DOI":"10.1093\/jpids\/piaa014","type":"journal-article","created":{"date-parts":[[2020,2,4]],"date-time":"2020-02-04T20:09:10Z","timestamp":1580846950000},"page":"213-216","source":"Crossref","is-referenced-by-count":23,"title":["Identification of an Emergent Pathogen, <i>Bartonella vinsonii<\/i>, Using Next-Generation Sequencing in a Patient With Culture-Negative Endocarditis"],"prefix":"10.1093","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3506-4034","authenticated-orcid":false,"given":"Rachel D","family":"Downey","sequence":"first","affiliation":[{"name":"Dell Children\u2019s Medical Center, Austin, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan M","family":"Russo","sequence":"additional","affiliation":[{"name":"Dell Children\u2019s Medical Center, Austin, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarmistha B","family":"Hauger","sequence":"additional","affiliation":[{"name":"Dell Children\u2019s Medical Center, Austin, Texas, USA"},{"name":"Dell Medical School, University of Texas at Austin, Austin, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donald K","family":"Murphey","sequence":"additional","affiliation":[{"name":"Dell Children\u2019s Medical Center, Austin, Texas, USA"},{"name":"Dell Medical School, University of Texas at Austin, Austin, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grace","family":"Marx","sequence":"additional","affiliation":[{"name":"Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thanhthao","family":"Huynh","sequence":"additional","affiliation":[{"name":"Infectious Diseases Pathology Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy M","family":"Denison","sequence":"additional","affiliation":[{"name":"Infectious Diseases Pathology Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Quirt","sequence":"additional","affiliation":[{"name":"Dell Children\u2019s Medical Center, Austin, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann","family":"Bailey","sequence":"additional","affiliation":[{"name":"Dell Children\u2019s Medical Center, Austin, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marisol","family":"Fernandez","sequence":"additional","affiliation":[{"name":"Dell Children\u2019s Medical Center, Austin, Texas, USA"},{"name":"Dell Medical School, University of Texas at Austin, Austin, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,2,24]]},"reference":[{"key":"2021032616093127700_CIT0001","doi-asserted-by":"crossref","first-page":"389","DOI":"10.3201\/eid1203.050931","article-title":"Bartonella spp. in pets and effect on human health","volume":"12","author":"Chomel","year":"2006","journal-title":"Emerg Infect Dis"},{"key":"2021032616093127700_CIT0002","article-title":"Human bartonellosis: an underappreciated public health problem?","volume":"4","author":"Cheslock","year":"2019","journal-title":"Trop Med Infect Dis"},{"key":"2021032616093127700_CIT0003","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1161\/CIR.0000000000000296","article-title":"AHA scientific statement: infective endocarditis in adults: diagnosis, antimicrobial therapy, and management of complications. 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