{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T16:21:13Z","timestamp":1792513273468,"version":"4.5.0"},"reference-count":50,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T00:00:00Z","timestamp":1722816000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100006356","name":"University of Southern Denmark","doi-asserted-by":"publisher","award":["OL 1021 2479"],"award-info":[{"award-number":["OL 1021 2479"]}],"id":[{"id":"10.13039\/501100006356","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009708","name":"Novo Nordisk Foundation","doi-asserted-by":"publisher","award":["OC005834"],"award-info":[{"award-number":["OC005834"]}],"id":[{"id":"10.13039\/501100009708","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010733","name":"Danish Childhood Cancer Foundation","doi-asserted-by":"publisher","award":["2022-8220"],"award-info":[{"award-number":["2022-8220"]}],"id":[{"id":"10.13039\/100010733","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Invasive aspergillosis (IA) is a potentially life-threatening complication of childhood acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). We conducted a systematic review and meta-analyses of studies on acute leukemia in children aged 0\u201317 years since 2000. Findings were reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. We included 24 studies with 3661 ALL patients and 1728 AML patients. IA cumulative incidence varied (0%\u201310% for ALL and 0%\u201318% for AML) across the studies. Pooled cumulative IA incidences were estimated at 3.2% (95% CI: 1.8%\u20135.8%) in ALL and 5.2% (95% CI: 3.1%\u20138.6%) in AML, with corresponding case fatality rates of 13.3% (95% CI: 6.3%\u201325.9%), and 7.8% (95% CI: 0.7%\u201351.2%), respectively. Our analysis highlights the impact of IA in childhood leukemia, underscoring the need to address strategies for prevention, early detection, and treatment of IA in pediatric leukemia.<\/jats:p>","DOI":"10.1093\/jpids\/piae079","type":"journal-article","created":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T11:25:00Z","timestamp":1722857100000},"page":"475-485","source":"Crossref","is-referenced-by-count":10,"title":["Occurrence and Case Fatality Rate of Invasive Aspergillosis in Children With Acute Leukemia: A Systematic Review and Meta-analysis"],"prefix":"10.1093","volume":"13","author":[{"given":"Rasmus Moeller","family":"Duus","sequence":"first","affiliation":[{"name":"Department of Pediatric Hematology and Oncology, Hans Christian Andersen Children\u2019s Hospital, Odense University Hospital , Odense ,","place":["Denmark"]},{"name":"Department of Molecular Medicine, University of Southern Denmark , Odense ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesper Bonnet","family":"Moeller","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine, University of Southern Denmark , Odense ,","place":["Denmark"]},{"name":"Danish Institute for Advanced Study, University of Southern Denmark , Odense ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathias","family":"Rathe","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hematology and Oncology, Hans Christian Andersen Children\u2019s Hospital, Odense University Hospital , Odense ,","place":["Denmark"]},{"name":"Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark , Odense 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