{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T17:45:22Z","timestamp":1790185522990,"version":"4.1.0"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T00:00:00Z","timestamp":1733961600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Nationwide Children\u2019s Hospital Intramural","award":["51135"],"award-info":[{"award-number":["51135"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,20]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Antibiotic durations for uncomplicated skin\/soft tissue infections (SSTI) often exceed the guideline-recommended 5\u20137 days. We assessed the effectiveness of a default duration order panel in the Electronic Health Record to reduce long prescriptions.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Cluster randomized trial of an SSTI order panel with default antibiotic durations (implemented 12\/2021), compared to a control panel (no decision support) in 14 pediatric primary care clinics. We assessed long prescription rates from 23 months before to 12 months after order panel implementation (1\/2020\u201312\/2022). Antibiotic duration was considered long if &amp;gt;5 days for cellulitis or drained abscess, or &amp;gt;7 days for undrained abscess, impetigo, or other SSTI.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>We included 1123 and 511 encounters in intervention and control clinics, respectively. In a piecewise generalized linear model, the long prescription rate decreased from 63.8% to 54.6% (absolute difference, \u22129.2%) in the intervention group and from 70.0% to 54.9% (absolute difference, \u221215.1%) in the control group. The relative change in trajectories from pre-panel to post-panel periods did not differ significantly between intervention and control groups (P\u2005=\u2005.488). Although used in only 29.4% of eligible encounters, intervention panel use had lower odds of long prescription compared to all other prescriptions (odds ratio 0.18).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>We did not detect an overall impact of an order panel with default durations in reducing long antibiotic prescriptions for SSTIs. When ordered from the intervention panel, prescriptions were usually guideline-concordant. Effective strategies to make choosing a default duration more automatic are necessary to further reduce long prescriptions.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jpids\/piae127","type":"journal-article","created":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T14:40:01Z","timestamp":1734014401000},"source":"Crossref","is-referenced-by-count":4,"title":["Default Antibiotic Order Durations for Skin and Soft Tissue Infections in Outpatient Pediatrics: A Cluster Randomized Trial"],"prefix":"10.1093","volume":"14","author":[{"given":"Kali A","family":"Broussard","sequence":"first","affiliation":[{"name":"Division of Pediatrics, Franciscan Missionaries of Our Lady Health System , Lafayette, Los Angeles ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan D","family":"Chaparro","sequence":"additional","affiliation":[{"name":"Divisions of Clinical Informatics and Pediatric Infectious Diseases, Department of Pediatrics, Nationwide Children\u2019s Hospital and The Ohio State University College of Medicine , Columbus, Ohio ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guliz","family":"Erdem","sequence":"additional","affiliation":[{"name":"Division of Pediatric Infectious Diseases, Department of Pediatrics, Nationwide Children\u2019s Hospital and The Ohio State University College of Medicine , Columbus, Ohio ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud","family":"Abdel-Rasoul","sequence":"additional","affiliation":[{"name":"Center for Biostatistics, The Ohio State University , Columbus, Ohio ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack","family":"Stevens","sequence":"additional","affiliation":[{"name":"Center for Biobehavioral Health, Center for Clinical Excellence, Nationwide Children\u2019s Hospital and The Ohio State University College of Medicine , Columbus, Ohio ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0079-937X","authenticated-orcid":false,"given":"Joshua R","family":"Watson","sequence":"additional","affiliation":[{"name":"Division of Pediatric Infectious Diseases, Department of Pediatrics, Center for Clinical Excellence, Nationwide Children\u2019s Hospital and The Ohio State University College of Medicine , Columbus, Ohio ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,12,12]]},"reference":[{"key":"2025013112425696200_CIT0001","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1542\/peds.2011-1337","article-title":"Antibiotic prescribing in ambulatory pediatrics in the United 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