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Pediatric infectious diseases clinicians are often called upon to determine the risk of meningitis requiring definitive treatment in the absence of optimal data. Pediatric clinicians can use clinical data, such as age, physical exam, and lab values to estimate the pre-test probability of meningitis and may be able to use ancillary testing, such as imaging and molecular microbiology, to refine the estimate. The goal of this review is to provide an evidence-based approach to this common scenario.<\/jats:p>","DOI":"10.1093\/jpids\/piag010","type":"journal-article","created":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T12:45:16Z","timestamp":1770813916000},"source":"Crossref","is-referenced-by-count":0,"title":["Management of Young Infants With Incomplete Evaluation for Meningitis"],"prefix":"10.1093","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6372-5274","authenticated-orcid":false,"given":"Zachary I","family":"Willis","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University of North Carolina at Chapel Hill , Chapel Hill, NC ,","place":["United States"]},{"name":"UNC Children\u2019s Hospital , Chapel Hill, NC ,","place":["United 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