{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T18:57:46Z","timestamp":1781636266863,"version":"3.54.5"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"6","funder":[{"name":"National Institute of Allergy and Infectious Diseases Vaccinology Training Program Grant","award":["T32AI074492"],"award-info":[{"award-number":["T32AI074492"]}]},{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["200-2012-53526"],"award-info":[{"award-number":["200-2012-53526"]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Institute of Allergy and Infectious Diseases Vaccinology Training Program Grant","award":["T32AI074492"],"award-info":[{"award-number":["T32AI074492"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Vaccination during pregnancy prevents disease in both the pregnant woman and infant via transplacental antibody transfer which may interfere with infant immune response to early childhood vaccination. Data on safety of COVID-19 vaccination during pregnancy in relation to non-targeted infant infections are lacking.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective cohort study of pregnancies from May 17, 2020, through February 15, 2021, across eight integrated healthcare systems in the Vaccine Safety Datalink to evaluate receipt of COVID-19 vaccination during second or third trimester of pregnancy on medically attended encounters for infections among infants up to 6 months. Adjusted incidence rate ratios (aIRRs) with 95% confidence intervals were estimated, controlling for potential confounders using inverse probability of treatment weighting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 42\u2009940 pregnancies, 14\u2009762 (34.4%) were exposed to COVID-19 vaccination during second or third trimester of pregnancy. COVID-19 vaccination during second or third trimester was not associated with an increase in non-targeted infant medically attended respiratory infections (aIRR 0.86, 95% CI 0.77, 0.95), including respiratory syncytial virus (RSV) (aIRR 0.78, 95% CI 0.65, 0.93) and was not associated with infant bloodstream (aIRR 1.03, 95% CI 0.77, 1.37) or meningeal (aIRR 0.54, 95% CI 0.19, 1.56) infections up to 6 months of life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>We found no increased risk for non-targeted medically attended infant respiratory infections and no association with bloodstream or meningeal infections from birth to 6 months of life following COVID-19 vaccination during second or third trimester of pregnancy. These findings support COVID-19 vaccination safety during pregnancy on the risk of non-targeted infant infections.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jpids\/piag036","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T11:33:15Z","timestamp":1780399995000},"source":"Crossref","is-referenced-by-count":0,"title":["Association Between COVID-19 Vaccination During Pregnancy and Safety Among Infants"],"prefix":"10.1093","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0515-7977","authenticated-orcid":false,"given":"Elizabeth M","family":"Quincer","sequence":"first","affiliation":[{"name":"Immunization Safety Office, Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention , Atlanta, GA ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela","family":"Vazquez-Benitez","sequence":"additional","affiliation":[{"name":"Pregnancy and Child Research Center, HealthPartners Institute , Minneapolis, MN ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric S","family":"Weintraub","sequence":"additional","affiliation":[{"name":"Immunization Safety Office, Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention , Atlanta, GA ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimp","family":"Walton","sequence":"additional","affiliation":[{"name":"Immunization Safety Office, Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention , Atlanta, GA ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lily","family":"Wang","sequence":"additional","affiliation":[{"name":"Immunization Safety Office, Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention , Atlanta, GA ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly K","family":"Vesco","sequence":"additional","affiliation":[{"name":"Center for Health Research , Kaiser Permanente Northwest, Portland, OR ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle L","family":"Henninger","sequence":"additional","affiliation":[{"name":"Center for Health Research , Kaiser Permanente Northwest, Portland, OR ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew F","family":"Daley","sequence":"additional","affiliation":[{"name":"Institute for Health Research, Kaiser Permanente Colorado , Denver, CO ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon J","family":"Hambidge","sequence":"additional","affiliation":[{"name":"Ambulatory Care Services, Denver Health , Denver, CO ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua T B","family":"Williams","sequence":"additional","affiliation":[{"name":"Ambulatory Care Services, Denver Health , Denver, CO ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James G","family":"Donahue","sequence":"additional","affiliation":[{"name":"Center for Clinical Epidemiology & Population Health, Marshfield Clinic Research Institute , Marshfield, WI ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8380-6215","authenticated-orcid":false,"given":"Ousseny","family":"Zerbo","sequence":"additional","affiliation":[{"name":"Vaccine Study Center, Kaiser Permanente Northern California , Oakland, CA ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3610-8841","authenticated-orcid":false,"given":"Darios","family":"Getahun","sequence":"additional","affiliation":[{"name":"Department of Research and Evaluation, Kaiser Permanente Southern California , Pasadena, CA ,","place":["United States"]},{"name":"Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine , Pasadena, CA ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa A","family":"Jackson","sequence":"additional","affiliation":[{"name":"Washington Health Research Institute , Kaiser Permanente Washington, Seattle, WA ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Candace C","family":"Fuller","sequence":"additional","affiliation":[{"name":"Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute , Boston, MA ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather S","family":"Lipkind","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Weill Cornell Medicine , New York, NY ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison L","family":"Naleway","sequence":"additional","affiliation":[{"name":"Center for Health Research , Kaiser Permanente Northwest, Portland, OR ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael M","family":"McNeil","sequence":"additional","affiliation":[{"name":"Immunization Safety Office, Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention , Atlanta, GA ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elyse O","family":"Kharbanda","sequence":"additional","affiliation":[{"name":"Pregnancy and Child Research Center, HealthPartners Institute , Minneapolis, MN ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,6,3]]},"reference":[{"key":"2026061614470686100_ref1","doi-asserted-by":"publisher","DOI":"10.3843\/GLOWM.419393","volume-title":"Maternal Immunization. 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