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We conducted a retrospective observational study on pediatric clinical cultures, performed between 2005 and 2017, that grew S aureus to determine temporal trends in antibiotic resistance. Although methicillin resistance declined, clindamycin and trimethoprim-sulfamethoxazole resistance increased significantly, especially among community-onset isolates.<\/jats:p>","DOI":"10.1093\/jpids\/piy062","type":"journal-article","created":{"date-parts":[[2018,6,27]],"date-time":"2018-06-27T19:21:49Z","timestamp":1530127309000},"page":"351-353","source":"Crossref","is-referenced-by-count":46,"title":["Increasing Clindamycin and Trimethoprim-Sulfamethoxazole Resistance in Pediatric Staphylococcus aureus Infections"],"prefix":"10.1093","volume":"8","author":[{"given":"Dina F","family":"Khamash","sequence":"first","affiliation":[{"name":"Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annie","family":"Voskertchian","sequence":"additional","affiliation":[{"name":"Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns 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