{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T23:50:07Z","timestamp":1770681007266,"version":"3.49.0"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2018,7,31]],"date-time":"2018-07-31T00:00:00Z","timestamp":1532995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AI125216"],"award-info":[{"award-number":["R01AI125216"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We report here 18 cases of pediatric group A streptococcal toxic shock syndrome, associated clinical findings, and bacterial molecular genetic characteristics discovered through whole-genome sequencing. This comparative whole-genome sequencing revealed unique gene content (speK) and polymorphisms (dpiB) in emm87 group A Streptococcus, the relative contributions of which, in combination with the host response, in the development of streptococcal toxic shock syndrome remain to be elucidated.<\/jats:p>","DOI":"10.1093\/jpids\/piy069","type":"journal-article","created":{"date-parts":[[2018,7,16]],"date-time":"2018-07-16T23:23:44Z","timestamp":1531783424000},"page":"265-268","source":"Crossref","is-referenced-by-count":10,"title":["Clinical Manifestations and Bacterial Genomic Analysis of Group A Streptococcus Strains That Cause Pediatric Toxic Shock Syndrome"],"prefix":"10.1093","volume":"8","author":[{"given":"Roman","family":"Deniskin","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Baylor College of Medicine and Texas Children\u2019s Hospital, Houston"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brittany","family":"Shah","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Pediatrics, Center for Antimicrobial Resistance and Microbial Genomics, McGovern Medical School, University of Texas Health Sciences Center at Houston"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Flor M","family":"Mu\u00f1oz","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Baylor College of Medicine and Texas Children\u2019s Hospital, Houston"},{"name":"Section of Infectious Diseases, Baylor College of Medicine and Texas Children\u2019s Hospital, Houston"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony R","family":"Flores","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Pediatrics, Center for Antimicrobial Resistance and Microbial Genomics, McGovern Medical School, University of 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