{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T05:58:51Z","timestamp":1790402331054,"version":"4.1.0"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2019,7,29]],"date-time":"2019-07-29T00:00:00Z","timestamp":1564358400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81573060"],"award-info":[{"award-number":["81573060"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81703136"],"award-info":[{"award-number":["81703136"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81803147"],"award-info":[{"award-number":["81803147"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Science & Technology Project Foundation of Jilin Province","award":["20160101047JC"],"award-info":[{"award-number":["20160101047JC"]}]},{"name":"Science & Technology Project Foundation of Jilin Province","award":["20170204060SF"],"award-info":[{"award-number":["20170204060SF"]}]},{"name":"Health Technology Innovation Project of Jilin Province","award":["2016J064"],"award-info":[{"award-number":["2016J064"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,7,13]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Pediatric patients make a substantial contribution to the epidemiologic profile of sporotrichosis in Jilin Province, a region of China in which the disease is strongly endemic. However, the exact epidemiologic and clinical manifestations of childhood sporotrichosis in China are unclear.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>The medical records of 704 pediatric patients aged &amp;lt;15 years with sporotrichosis diagnosed by fungus culture at the Department of Dermatology at the First Hospital of Jilin University in a 7-year period (January 2010 to December 2016) were reviewed retrospectively. The patients were from rural areas of Jilin Province, located in northeast China.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Among the 704 pediatric patients, the male\/female ratio was 1.41:1, and the highest incidence of sporotrichosis (63%) occurred in those aged 0 to 6 years; 561 patients (80%) contracted sporotrichosis in a colder month. Overall, 655 (93%) patients had lesions in the facial region, whereas 602 (86%) patients had fixed cutaneous sporotrichosis. The incidence of the fixed cutaneous form in the 0- to 6-year age group was significantly higher than that in the 7- to 14-year age group (P = .009). Patients were treated with 10% potassium iodide solution, itraconazole, or terbinafine.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The characteristics of pediatric sporotrichosis in Jilin Provence include the following: (1) a more frequent occurrence in the colder months; (2) the facial region is affected predominantly, in most cases manifesting in the fixed cutaneous form; and (3) significantly more cases occur in younger children than in older ones. Decaying cornstalks used as fire materials might be the source of infection in this population; however, additional research is needed to explore the exact mechanism of infection.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jpids\/piz052","type":"journal-article","created":{"date-parts":[[2019,7,29]],"date-time":"2019-07-29T20:06:37Z","timestamp":1564430797000},"page":"342-348","source":"Crossref","is-referenced-by-count":21,"title":["Pediatric Sporotrichosis in Jilin Province of China (2010\u20132016): a Retrospective Study of 704 Cases"],"prefix":"10.1093","volume":"9","author":[{"given":"Lei","family":"Yao","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venerology, First Hospital of Jilin University, Changchun, Jilin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Song","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venerology, First Hospital of Jilin University, Changchun, Jilin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Cui","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venerology, First Hospital of Jilin University, Changchun, Jilin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-Feng","family":"Zhou","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venerology, First Hospital of Jilin University, Changchun, Jilin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu-Xia","family":"Zhong","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venerology, First Hospital of Jilin University, Changchun, Jilin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Yang","family":"Zhao","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venerology, First Hospital of Jilin University, Changchun, Jilin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan-Shan","family":"Li","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venerology, First Hospital of Jilin University, Changchun, Jilin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,7,29]]},"reference":[{"key":"2020071317224204900_CIT0001","first-page":"286","article-title":"On refractory subcutaneous abscesses caused by a fungus possibly related to the sporotricha","volume":"9","author":"Schenck","year":"1898","journal-title":"Bull Johns Hopkins Hosp"},{"key":"2020071317224204900_CIT0002","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1046\/j.1365-2230.2002.01087.x","article-title":"Sporotrichosis","volume":"27","author":"Morris-Jones","year":"2002","journal-title":"Clin Exp Dermatol"},{"key":"2020071317224204900_CIT0003","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1111\/j.1525-1470.2007.00452.x","article-title":"Sporotrichosis in childhood: clinical and therapeutic experience in 25 patients","volume":"24","author":"Bonifaz","year":"2007","journal-title":"Pediatr Dermatol"},{"key":"2020071317224204900_CIT0004","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.jaad.2004.11.046","article-title":"Epidemiology of sporotrichosis: a study of 304 cases in Brazil","volume":"52","author":"da Rosa","year":"2005","journal-title":"J Am Acad Dermatol"},{"key":"2020071317224204900_CIT0005","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1017\/S0950268807009727","article-title":"An epidemic of sporotrichosis in Rio de Janeiro, Brazil: epidemiological aspects of a series of cases","volume":"136","author":"Barros","year":"2008","journal-title":"Epidemiol Infect"},{"key":"2020071317224204900_CIT0006","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1086\/313607","article-title":"Sporotrichosis in Peru: description of an area of hyperendemicity","volume":"30","author":"Pappas","year":"2000","journal-title":"Clin Infect Dis"},{"key":"2020071317224204900_CIT0007","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1086\/345437","article-title":"Population-based surveillance and a case-control study of risk factors for endemic lymphocutaneous sporotrichosis in Peru","volume":"36","author":"Lyon","year":"2003","journal-title":"Clin Infect Dis"},{"key":"2020071317224204900_CIT0008","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1111\/j.1365-4632.2012.05849.x","article-title":"Epidemiology of sporotrichosis in Venezuela","volume":"52","author":"Mata-Essayag","year":"2013","journal-title":"Int J Dermatol"},{"key":"2020071317224204900_CIT0009","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1111\/j.1468-3083.2011.04389.x","article-title":"Report of 457 sporotrichosis cases from Jilin Province, Northeast China, a serious endemic region","volume":"27","author":"Song","year":"2013","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2020071317224204900_CIT0010","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1111\/ajd.12286","article-title":"Eyelid sporotrichosis: unique clinical findings in 72 patients","volume":"57","author":"Zhang","year":"2016","journal-title":"Australas J Dermatol"},{"key":"2020071317224204900_CIT0011","doi-asserted-by":"crossref","first-page":"e1673","DOI":"10.1371\/journal.pntd.0001673","article-title":"Sporotrichosis in sub-Himalayan India","volume":"6","author":"Verma","year":"2012","journal-title":"PLoS Negl Trop Dis"},{"key":"2020071317224204900_CIT0012","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1111\/myc.12158","article-title":"A survey of 165 sporotrichosis cases examined in Nagasaki prefecture from 1951 to 2012","volume":"57","author":"Takenaka","year":"2014","journal-title":"Mycoses"},{"key":"2020071317224204900_CIT0013","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3767\/003158515X687416","article-title":"Phylogeography and evolutionary patterns in Sporothrix spanning more than 14 000 human and animal case reports","volume":"35","author":"Zhang","year":"2015","journal-title":"Persoonia"},{"key":"2020071317224204900_CIT0014","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1111\/myc.12751","article-title":"A population genetics analysis in clinical isolates of Sporothrix schenckii based on calmodulin and calcium\/calmodulin-dependent kinase partial gene sequences","volume":"61","author":"Rangel-Gamboa","year":"2018","journal-title":"Mycoses"},{"key":"2020071317224204900_CIT0015","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1099\/jmm.0.000451","article-title":"Origin and distribution of Sporothrix globosa causing sapronoses in Asia","volume":"66","author":"Moussa","year":"2017","journal-title":"J Med Microbiol"},{"key":"2020071317224204900_CIT0016","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1093\/mmy\/myu062","article-title":"Global epidemiology of sporotrichosis","volume":"53","author":"Chakrabarti","year":"2015","journal-title":"Med Mycol"},{"key":"2020071317224204900_CIT0017","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1097\/INF.0b013e31815bf309","article-title":"Endemic of zoonotic sporotrichosis: profile of cases in children","volume":"27","author":"Barros","year":"2008","journal-title":"Pediatr Infect Dis J"},{"key":"2020071317224204900_CIT0018","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/j.1439-0507.2004.01058.x","article-title":"Cutaneous sporotrichosis in Himachal Pradesh, India","volume":"48","author":"Mahajan","year":"2005","journal-title":"Mycoses"},{"key":"2020071317224204900_CIT0019","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/BF00437450","article-title":"Statistical survey of 150 cases with sporotrichosis","volume":"102","author":"Kusuhara","year":"1988","journal-title":"Mycopathologia"},{"key":"2020071317224204900_CIT0020","first-page":"230","article-title":"The report of 108 cases of pediatric sporotrichosis","volume":"12","author":"Song","year":"1998","journal-title":"Chin J Derm Venereol"},{"key":"2020071317224204900_CIT0021","doi-asserted-by":"crossref","first-page":"257","DOI":"10.3314\/jjmm.43.257","article-title":"Environmental isolates of Sporothrix schenckii in China","volume":"43","author":"Ishizaki","year":"2002","journal-title":"Nihon Ishinkin Gakkai Zasshi"},{"key":"2020071317224204900_CIT0022","first-page":"676","article-title":"Clinical analysis of 62 cases of pediatric sporotrichosis","volume":"21","author":"Li","year":"2003","journal-title":"Clin Pediatr"},{"key":"2020071317224204900_CIT0023","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1111\/j.1365-4632.2010.04724.x","article-title":"Infant sporotrichosis in northeast China: a report of 15 cases","volume":"50","author":"Song","year":"2011","journal-title":"Int J Dermatol"},{"key":"2020071317224204900_CIT0024","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1111\/ijd.13643","article-title":"Sporotrichosis among children of a hyperendemic area in Peru: an 8-year retrospective study","volume":"56","author":"Ram\u00edrez Soto","year":"2017","journal-title":"Int J Dermatol"},{"key":"2020071317224204900_CIT0025","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1001\/archinte.1997.00440370135014","article-title":"Spook house sporotrichosis. A point-source outbreak of sporotrichosis associated with hay bale props in a Halloween haunted-house","volume":"157","author":"Dooley","year":"1997","journal-title":"Arch Intern Med"},{"key":"2020071317224204900_CIT0026","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/j.1440-0960.1998.tb01239.x","article-title":"Epidemic cutaneous sporotrichosis: report of 16 cases in Queensland due to mouldy hay","volume":"39","author":"Conias","year":"1998","journal-title":"Australas J Dermatol"},{"key":"2020071317224204900_CIT0027","doi-asserted-by":"crossref","first-page":"272376","DOI":"10.1155\/2014\/272376","article-title":"Sporotrichosis: an overview and therapeutic options","volume":"2014","author":"Mahajan","year":"2014","journal-title":"Dermatol Res Pract"},{"key":"2020071317224204900_CIT0028","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s11046-013-9668-6","article-title":"Phenotypic and molecular identification of Sporothrix isolates of clinical origin in northeast China","volume":"176","author":"Yu","year":"2013","journal-title":"Mycopathologia"},{"key":"2020071317224204900_CIT0029","doi-asserted-by":"crossref","first-page":"e88","DOI":"10.1038\/emi.2017.75","article-title":"Genetic variation of Sporothrix globosa isolates from diverse geographic and clinical origins in China","volume":"6","author":"Zhao","year":"2017","journal-title":"Emerg Microbes Infect"},{"key":"2020071317224204900_CIT0030","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1080\/13693780701625131","article-title":"Comparison of virulence of different Sporothrix schenckii clinical isolates using experimental murine model","volume":"45","author":"Brito","year":"2007","journal-title":"Med Mycol"},{"key":"2020071317224204900_CIT0031","first-page":"456","article-title":"Guidelines for the diagnosis and treatment of sporotrichosis","volume":"49","author":"Li","year":"2016","journal-title":"Chin J Traumatol"},{"key":"2020071317224204900_CIT0032","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1086\/522765","article-title":"Clinical practice guidelines for the management of sporotrichosis: 2007 update by the Infectious Diseases Society of America","volume":"45","author":"Kauffman","year":"2007","journal-title":"Clin Infect Dis"}],"container-title":["Journal of the Pediatric Infectious Diseases Society"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jpids\/article-pdf\/9\/3\/342\/33493011\/piz052.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jpids\/article-pdf\/9\/3\/342\/33493011\/piz052.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T22:32:55Z","timestamp":1594679575000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jpids\/article\/9\/3\/342\/5540409"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,29]]},"references-count":32,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2019,7,29]]},"published-print":{"date-parts":[[2020,7,13]]}},"URL":"https:\/\/doi.org\/10.1093\/jpids\/piz052","relation":{},"ISSN":["2048-7207"],"issn-type":[{"value":"2048-7207","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,7]]},"published":{"date-parts":[[2019,7,29]]}}}