{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T11:08:17Z","timestamp":1740136097034,"version":"3.37.3"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"Supplement_1","license":[{"start":{"date-parts":[[2022,8,15]],"date-time":"2022-08-15T00:00:00Z","timestamp":1660521600000},"content-version":"vor","delay-in-days":2,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Grants-in-Aid for Scientific Research","doi-asserted-by":"publisher","award":["26257501","19H01149"],"award-info":[{"award-number":["26257501","19H01149"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"name":"JSPS KAKENHI","award":["JP19H01149"],"award-info":[{"award-number":["JP19H01149"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,8,13]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The aim of overview is to present the pooled data of published internal dose estimates and the results of corresponding analysis of internal irradiation features of experimental mice and rats after exposure to sprayed neutron activated radioactive 56MnO2. These dose estimates were conducted in a framework of multicenter international study to investigate biological effects as a result of exposure to sprayed radioactive 56MnO2 microparticles. Radionuclide 56Mn (T1\/2\u2009=\u20092.58\u00a0h) is one of the main gamma-beta emitters during the first hours after neutron activation of soil following nuclear explosion. It was concluded that there are three groups of organs of mice and rats, the radiation doses of which differ by approximately an order of magnitude: the group with the highest radiation doses (large and small intestine, stomach, skin and lungs), the group with lowered radiation doses (eyes, esophagus, trachea), the group with the lowest radiation doses (liver, heart, kidneys). The radiation doses to organs are proportional to the activity of the sprayed radioactive powder. The distribution of internal radiation doses among organs of experimental mice of different strains but of the same age was practically the same in case of exposure to the same activity of sprayed 56MnO2 powder. Doses of internal irradiation of experimental mice substantially exceed the doses of internal irradiation of experimental rats exposed to the same activities of the sprayed 56MnO2 powder. The data presented in the overview can be helpful for further investigation and for interpretation of the biological effects of this type of irradiation.<\/jats:p>","DOI":"10.1093\/jrr\/rrac043","type":"journal-article","created":{"date-parts":[[2023,1,8]],"date-time":"2023-01-08T03:30:13Z","timestamp":1673148613000},"page":"i8-i15","source":"Crossref","is-referenced-by-count":3,"title":["Overview and analysis of internal radiation dose estimates in experimental animals in a framework of international studies of the sprayed neutron-induced 56Mn radioactive microparticles effects"],"prefix":"10.1093","volume":"63","author":[{"given":"Valeriy","family":"Stepanenko","sequence":"first","affiliation":[{"name":"A. Tsyb Medical Radiological Research Center \u2013 Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation , Koroleva Str., 4., Obninsk, Kaluga Region 2490036, Russian Federation"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrey","family":"Kaprin","sequence":"additional","affiliation":[{"name":"National Medical Research Radiological Center of the Ministry of Health of the Russian Federation , Koroleva Str., 4., Obninsk, Kaluga Region 2490036, Russian Federation"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergey","family":"Ivanov","sequence":"additional","affiliation":[{"name":"A. Tsyb Medical Radiological Research Center \u2013 Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation , Koroleva Str., 4., Obninsk, Kaluga Region 2490036, Russian Federation"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Shegay","sequence":"additional","affiliation":[{"name":"National Medical Research Radiological Center of the Ministry of Health of the Russian Federation , Koroleva Str., 4., Obninsk, Kaluga Region 2490036, Russian Federation"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viktoria","family":"Bogacheva","sequence":"additional","affiliation":[{"name":"A. Tsyb Medical Radiological Research Center \u2013 Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation , Koroleva Str., 4., Obninsk, Kaluga Region 2490036, Russian Federation"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaharu","family":"Hoshi","sequence":"additional","affiliation":[{"name":"The Center for Peace , Hiroshima University, Higashi-senda-machi, Naka-ku, Hiroshima 730-0053, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,8,13]]},"reference":[{"key":"2023010803281129100_ref1","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1097\/HP.0b013e31828ca73a","article-title":"Workshop report on atomic bomb dosimetry\u2014residual radiation exposure: recent research and suggestions for future studies","volume":"105","author":"Kerr","year":"2013","journal-title":"Health 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