{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T21:52:48Z","timestamp":1791496368631,"version":"4.3.4"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2022,9,16]],"date-time":"2022-09-16T00:00:00Z","timestamp":1663286400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP18K07769"],"award-info":[{"award-number":["JP18K07769"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP22K07645"],"award-info":[{"award-number":["JP22K07645"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,12,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The polymer gel dosimeter has been proposed for use as a 3D dosimeter for complex dose distribution measurement of high dose-rate (HDR) brachytherapy. However, various shapes of catheter\/applicator for sealed radioactive source transport used in clinical cases must be placed in the gel sample. The absorbed dose readout for the magnetic resonance (MR)-based polymer gel dosimeters requires calibration data for the dose-transverse relaxation rate (R2) response. In this study, we evaluated in detail the dose uncertainty and dose resolution of three calibration methods, the multi-sample and distance methods using the Ir-192 source and the linear accelerator (linac) method using 6MV X-rays. The use of Ir-192 sources increases dose uncertainty with steep dose gradients. We clarified that the uniformly irradiated gel sample improved the signal-to-noise ratio (SNR) due to the large slice thickness of MR images and could acquire an accurate calibration curve using the linac method. The curved tandem and ovoid applicator used for intracavitary irradiation of HDR brachytherapy for cervical cancer were reproduced with a glass tube to verify the dose distribution. The results of comparison with the treatment planning system (TPS) calculation by gamma analysis on the 3%\/2\u00a0mm criterion were in good agreement with a gamma pass rate of 90%. In addition, the prescription dose could be evaluated accurately. We conclude that it is easy to place catheter\/applicator in the polymer gel dosimeters, making them a useful tool for verifying the 3D dose distribution of HDR brachytherapy with accurate calibration methods.<\/jats:p>","DOI":"10.1093\/jrr\/rrac053","type":"journal-article","created":{"date-parts":[[2022,9,16]],"date-time":"2022-09-16T01:57:22Z","timestamp":1663293442000},"page":"838-848","source":"Crossref","is-referenced-by-count":12,"title":["Verification of dose distribution in high dose-rate brachytherapy for cervical cancer using a normoxic <i>N<\/i>-vinylpyrrolidone polymer gel dosimeter"],"prefix":"10.1093","volume":"63","author":[{"given":"Yusuke","family":"Watanabe","sequence":"first","affiliation":[{"name":"School of Allied Health Sciences, Kitasato University , 1-15-1 Kitazato, Minami-ku, Sagamihara, Kanagawa, 252-0373 , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Maeyama","sequence":"additional","affiliation":[{"name":"School of Science, Kitasato University , 1-15-1 Kitazato, Minami-ku, Sagamihara, Kanagawa, 252-0373 , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinya","family":"Mizukami","sequence":"additional","affiliation":[{"name":"School of Allied Health Sciences, Kitasato University , 1-15-1 Kitazato, Minami-ku, Sagamihara, Kanagawa, 252-0373 , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidenobu","family":"Tachibana","sequence":"additional","affiliation":[{"name":"Radiation Safety and Quality Assurance division, National Cancer Center Hospital East , 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577 , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsuyoshi","family":"Terazaki","sequence":"additional","affiliation":[{"name":"Department of Radiology, Yokohama City Minato Red Cross Hospital , 3-12-1 Shinyamashita, Naka-ku, Yokohama, Kanagawa, 231-8682 , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideyuki","family":"Takei","sequence":"additional","affiliation":[{"name":"Quantum Life and Medical Science Directorate, National Institute for Quantum Science and Technology , 4-9-1 Anagawa, Inage-ku, Chiba-shi, Chiba, 263-8555 , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Muraishi","sequence":"additional","affiliation":[{"name":"School of Allied Health Sciences, Kitasato University , 1-15-1 Kitazato, Minami-ku, Sagamihara, Kanagawa, 252-0373 , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsutomu","family":"Gomi","sequence":"additional","affiliation":[{"name":"School of Allied Health Sciences, Kitasato University , 1-15-1 Kitazato, Minami-ku, Sagamihara, Kanagawa, 252-0373 , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin-ichiro","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, Hiroshima International University , 555-36 Kurosegakuendai, Higashihiroshima, Hiroshima, 739-2695 , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,9,16]]},"reference":[{"key":"2022120704131671000_ref1","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.radonc.2004.12.015","article-title":"Gynaecological (GYN) GEC-ESTRO Working Group. Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (I): concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV","volume":"74","author":"Haie-Meder","year":"2005","journal-title":"Radiother Oncol"},{"key":"2022120704131671000_ref2","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.radonc.2005.11.014","article-title":"GEC ESTRO Working Group. Recommendations from gynaecological (GYN) GEC ESTRO working group (II): concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy-3D dose volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology","volume":"78","author":"P\u00f6tter","year":"2006","journal-title":"Radiother Oncol"},{"key":"2022120704131671000_ref3","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1118\/1.3514120","article-title":"Dosimetry tools and techniques for IMRT","volume":"38","author":"Low","year":"2011","journal-title":"Med Phys"},{"key":"2022120704131671000_ref4","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1118\/1.597316","article-title":"Comprehensive QA for radiation oncology: report of AAPM Radiation Therapy Committee Task Group 40","volume":"21","author":"Kutcher","year":"1994","journal-title":"Med Phys"},{"key":"2022120704131671000_ref5","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1118\/1.597966","article-title":"Code of practice for brachytherapy physics: report of the AAPM Radiation Therapy Committee Task Group No. 56. 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