{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T16:22:33Z","timestamp":1788366153785,"version":"build-2803163510"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2024,6,27]],"date-time":"2024-06-27T00:00:00Z","timestamp":1719446400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"JSPS KAKENHI","award":["JP22K15583"],"award-info":[{"award-number":["JP22K15583"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,22]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The aim of this study was to investigate planning target volume (PTV) margin in online adaptive radiation therapy (oART) for gastric mucosa-associated lymphoid tissue (MALT) lymphomas. Four consecutive patients with gastric MALT lymphoma \ufeffwho received oART (30\u00a0Gy in 15 fractions) on the oART system were included in this study. One hundred and twenty cone-beam computed tomography (CBCT) scans acquired pre- and post-treatment of 60 fractions for all patients were used to evaluate intra- and interfractional motions. Patients were instructed on breath-holding at exhalation during image acquisition. To assess the intrafraction gastric motion, different PTVs were created by isotropically extending the CTV contoured on a pre-CBCT image (CTVpre) at1 mm intervals. Intrafraction motion was defined as the amount of expansion covering the contoured CTV on post-CBCT images (CTVpost). Interfractional motion was defined as the amount of reference CTV expansion that could cover each CTVpre, as well as the evaluation of the intrafractional motion. PTV margins were estimated from the cumulative proportion of fraction covering the intra- and interfractional motions. The extent of expansion covering the CTVs in 90% of fractions was adopted as the PTV margin. The PTV margin for intrafractional gastric motion using the oART system with breath-holding was 14\u00a0mm. In contrast, the PTV margin for interfractional gastric organ motion without the oART system was 25\u00a0mm. These results indicated that the oART system can reduce the PTV margin by &amp;gt;10\u00a0mm. Our results could be valuable data for oART cases.<\/jats:p>","DOI":"10.1093\/jrr\/rrae052","type":"journal-article","created":{"date-parts":[[2024,6,27]],"date-time":"2024-06-27T13:18:14Z","timestamp":1719494294000},"page":"507-511","source":"Crossref","is-referenced-by-count":8,"title":["Evaluation of PTV margin in CBCT-based online adaptive radiation therapy for gastric mucosa-associated lymphoid tissue lymphoma"],"prefix":"10.1093","volume":"65","author":[{"given":"Taka-aki","family":"Hirose","sequence":"first","affiliation":[{"name":"Division of Radiology , Department of Medical Technology, , 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582 , Japan"},{"name":"Kyushu University Hospital , Department of Medical Technology, , 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582 , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanori","family":"Takaki","sequence":"additional","affiliation":[{"name":"Department of Clinical Radiology , Graduate School of Medical Sciences, , 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582 , Japan"},{"name":"Kyushu University , Graduate School of Medical Sciences, , 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582 , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Shibayama","sequence":"additional","affiliation":[{"name":"Division of Radiology , Department of Medical Technology, , 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582 , Japan"},{"name":"Kyushu University Hospital , Department of Medical Technology, , 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582 , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-ichi","family":"Fukunaga","sequence":"additional","affiliation":[{"name":"Division of Radiology , Department of Medical Technology, , 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582 , Japan"},{"name":"Kyushu University Hospital , Department of Medical Technology, , 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582 , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toyoyuki","family":"Kato","sequence":"additional","affiliation":[{"name":"Division of Radiology , Department of Medical Technology, , 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582 , Japan"},{"name":"Kyushu University Hospital , Department of Medical Technology, , 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582 , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadamasa","family":"Yoshitake","sequence":"additional","affiliation":[{"name":"Department of Clinical Radiology , Graduate School of Medical Sciences, , 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582 , Japan"},{"name":"Kyushu University , Graduate School of Medical Sciences, , 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582 , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kousei","family":"Ishigami","sequence":"additional","affiliation":[{"name":"Department of Clinical Radiology , Graduate School of Medical Sciences, , 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582 , Japan"},{"name":"Kyushu University , Graduate School of Medical Sciences, , 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582 , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,6,27]]},"reference":[{"key":"2024072301304965600_ref1","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.cgh.2009.07.017","article-title":"Effects of helicobacter pylori eradication on early stage gastric mucosa-associated lymphoid tissue lymphoma","volume":"8","author":"Zullo","year":"2010","journal-title":"Clin Gastroenterol Hepatol"},{"key":"2024072301304965600_ref2","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.bpg.2009.12.002","article-title":"Role of radiotherapy in the treatment of lymphomas of the gastrointestinal tract","volume":"24","author":"Aleman","year":"2010","journal-title":"Best Pract Res Clin 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