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Methods for predictive inference have been developed under a variety of assumptions, often\u2014for instance, in standard conformal prediction\u2014relying on the invariance of the distribution of the data under special groups of transformations such as permutation groups. Moreover, many existing methods for predictive inference aim to predict unobserved outcomes in sequences of feature-outcome observations. Meanwhile, there is interest in predictive inference under more general observation models (e.g. for partially observed features) and for data satisfying more general distributional symmetries (e.g. rotationally invariant observations in physics). Here, we propose SymmPI, a methodology for predictive inference when data distributions have general group symmetries in arbitrary observation models. Our methods leverage the novel notion of distributionally equivariant transformations, which process the data while preserving their distributional invariances. We show that SymmPI has valid coverage under distributional invariance and characterize its performance under distribution shift, recovering recent results as special cases. We apply SymmPI to predict unobserved values associated with vertices in a network, where the distribution is unchanged under relabellings that keep the network structure unchanged. In several simulations in a two-layer hierarchical model, and in an empirical data analysis example, SymmPI performs favourably compared with existing methods.<\/jats:p>","DOI":"10.1093\/jrsssb\/qkaf022","type":"journal-article","created":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T05:23:41Z","timestamp":1744867421000},"page":"1353-1381","source":"Crossref","is-referenced-by-count":1,"title":["SymmPI: predictive inference for data with group symmetries"],"prefix":"10.1093","volume":"87","author":[{"given":"Edgar","family":"Dobriban","sequence":"first","affiliation":[{"name":"Department of Statistics and Data Science, University of Pennsylvania , Philadelphia, PA ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6818-4083","authenticated-orcid":false,"given":"Mengxin","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Statistics and Data Science, Washington University in St. Louis , St. 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