{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T21:39:21Z","timestamp":1773092361642,"version":"3.50.1"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2020,3,4]],"date-time":"2020-03-04T00:00:00Z","timestamp":1583280000000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Acute appendicitis is the most common surgical pathology worldwide, frequently, the patient history and clinical examination are so similar to other appendicular pathologies that preoperative diagnosis is almost impossible for the medical team. Neuroma of the appendix is a rare tumor of neural origin that usually resembles the symptoms of acute appendicitis. Pathology along with close follow-ups are key, as the diagnosis is based on the presence of nerve neuronal cells in the appendicular lumen. Surgical treatment is recommended due to the possibility of malignancy. We present a case of a 32-year-old male patient who presented with symptoms of acute abdomen, surgery was performed and appendectomy was completed. Neuroma of the appendix was the final diagnosis.<\/jats:p>","DOI":"10.1093\/jscr\/rjaa023","type":"journal-article","created":{"date-parts":[[2020,2,2]],"date-time":"2020-02-02T20:06:39Z","timestamp":1580673999000},"source":"Crossref","is-referenced-by-count":6,"title":["Neuroma of the appendix, a rare cause of appendicitis and an important reason for close follow-up"],"prefix":"10.1093","volume":"2020","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0001-9070","authenticated-orcid":false,"given":"Gabriel A","family":"Molina","sequence":"first","affiliation":[{"name":"Department of General Surgery, Hospital IESS Quito Sur Quito-Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco Alejandro","family":"Torres","sequence":"first","affiliation":[{"name":"Department of General Surgery, Hospital IESS Quito Sur Quito-Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauro Santiago","family":"Montenegro","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Division of Pathology, Hospital IESS Quito Sur Quito-Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gery Daniel","family":"S\u00e1nchez","sequence":"first","affiliation":[{"name":"Department of General Surgery, Hospital IESS Quito Sur Quito-Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto Carlos","family":"Arcia","sequence":"first","affiliation":[{"name":"Department of General Surgery, Hospital IESS Quito Sur Quito-Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan Jos\u00e9","family":"Enr\u00edquez","sequence":"first","affiliation":[{"name":"Department of General Surgery, Hospital IESS Quito Sur Quito-Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andres Vinicio","family":"Ayala","sequence":"first","affiliation":[{"name":"Department of General Surgery, Hospital IESS Quito Sur Quito-Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica Elizabeth","family":"Orejuela","sequence":"first","affiliation":[{"name":"Department of General Surgery, Chief of General Surgery Hospital IESS Quito Sur Quito-Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,3,2]]},"reference":[{"key":"2020030321413521300_ref1","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1097\/00000478-198611000-00008","article-title":"Neuromas of the appendix: a light-microscopic, immunohistochemical and electron-microscopic study of 20 cases","volume":"10","author":"Stanley","year":"1986","journal-title":"Am J Surg Pathol"},{"key":"2020030321413521300_ref2","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/BF00619574","article-title":"The neuroendocrine system of normal human appendix, ileum and colon, and in neurogenic appendicopathy","volume":"399","author":"H\u00f6fler","year":"1983","journal-title":"Virchows Arch A, Pathol Anat Histopathol"},{"key":"2020030321413521300_ref3","first-page":"181","article-title":"Carcinoids (Argentaffin-cell Tumors) and nerve hyperplasia of the appendicular mucosa","volume":"4","author":"Masson","year":"1928","journal-title":"Am J Pathol"},{"key":"2020030321413521300_ref4","first-page":"2631","article-title":"Appendiceal neuroma: an uncommon entity","volume":"6","author":"Jagtap","year":"2019","journal-title":"Surgery"},{"key":"2020030321413521300_ref5","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s12262-012-0645-y","article-title":"Routine histopathologic examination of two common surgical specimens-appendix and gallbladder: is it a waste of expertise and hospital resources?","volume":"76","author":"Ramraje","year":"2014","journal-title":"Indian J Surg"},{"key":"2020030321413521300_ref6","first-page":"332","article-title":"Appendiceal neuroma: report of an elusive neuroma","volume":"32","author":"Gupta","year":"2020","journal-title":"Trop Gastroenterol"},{"key":"2020030321413521300_ref7","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1007\/s12262-016-1557-z","article-title":"Incidental findings in routine Histopathological examination of appendectomy specimens; retrospective analysis of 1970 patients","volume":"80","author":"Dincel","year":"2018","journal-title":"Indian J Surg"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jscr\/article-pdf\/2020\/3\/rjaa023\/32743665\/rjaa023.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jscr\/article-pdf\/2020\/3\/rjaa023\/32743665\/rjaa023.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,4]],"date-time":"2020-03-04T02:41:44Z","timestamp":1583289704000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjaa023\/5771445"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,1]]},"references-count":7,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,3,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjaa023","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,3]]},"published":{"date-parts":[[2020,3,1]]},"article-number":"rjaa023"}}