{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:06:59Z","timestamp":1753877219942,"version":"3.41.2"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2020,7,31]],"date-time":"2020-07-31T00:00:00Z","timestamp":1596153600000},"content-version":"vor","delay-in-days":30,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Deanship of Scientific Research at King Saud University"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>It is extremely rare for malignant mesothelioma to present as gastrointestinal polyps. This case report documents the presentation of malignant mesothelioma in a 72-year-old as rectal bleeding and weight loss. Endoscopically, there were multiple gastric and colonic polyps. Histopathologically, there were atypical cells in the lamina propria with benign surface epithelium. The cells tested positive for cytokeratin, calretinin and D2\u201340 and negative for CD45, CD117, Ber-EP4 and CEA, confirming the diagnosis of metastatic mesothelioma. A computed tomography scan of the chest showed nodular thickening of the left lower pleura that was compatible with a diagnosis of primary pleural mesothelioma. We conclude that metastatic mesothelioma can sometimes present as gastrointestinal polyps.<\/jats:p>","DOI":"10.1093\/jscr\/rjaa203","type":"journal-article","created":{"date-parts":[[2020,6,21]],"date-time":"2020-06-21T19:12:04Z","timestamp":1592766724000},"source":"Crossref","is-referenced-by-count":0,"title":["Metastatic pleural mesothelioma presenting initially as multiple gastric and colonic polyps"],"prefix":"10.1093","volume":"2020","author":[{"given":"Ahmed","family":"Alhumidi","sequence":"first","affiliation":[{"name":"Professor and consultant of pathology, Department of pathology, College of medicine, King Saud University, Riyadh, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdulmalik","family":"Alqahtani","sequence":"additional","affiliation":[{"name":"Anatomic Pathology Resident, Department of pathology, Prince Sultan Military Medical City, Riyadh, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,7,31]]},"reference":[{"key":"2020073110270796700_ref1","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/0007-0971(83)90068-2","article-title":"Malignant mesothelioma 1982, review of 4710 published cases","volume":"77","author":"Hillerdal","year":"1983","journal-title":"Br J Dis Chest"},{"volume-title":"Clinical Presentation, Diagnosis, and Staging of Malignant Pleural Mesothelioma","author":"Sterman","key":"2020073110270796700_ref2"},{"key":"2020073110270796700_ref3","first-page":"159","article-title":"Pleural mesothelioma","volume":"65","author":"Dunnill","year":"1984","journal-title":"Eur J Respir Dis"},{"key":"2020073110270796700_ref4","doi-asserted-by":"crossref","first-page":"625","DOI":"10.5694\/j.1326-5377.1990.tb126277.x","article-title":"Sarcomatous mesothelioma of the pleura with cerebral metastases","volume":"153","author":"Nielson","year":"1990","journal-title":"Med J Aust"},{"key":"2020073110270796700_ref5","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/0046-8177(94)90192-9","article-title":"Immunocytochemical characterization of cell lines from human malignant mesothelioma. Characterization of human mesothelioma ceil lines by immunohistochemistry with a panel of monoclonal antibodies","volume":"25","author":"Zeng","year":"1994","journal-title":"Hum Pathol"},{"key":"2020073110270796700_ref6","first-page":"179","article-title":"Immunocytochemistry in the diagnosis of effusions: use of logistic regression to select a panel of antibodies to distinguish adenocarcinomas from mesothelial proliferations","volume":"6","author":"Frisman","year":"1993","journal-title":"Mod Pathol"},{"key":"2020073110270796700_ref7","first-page":"174","article-title":"Malignant pleural mesothelioma presenting as rectal polyp: a case report and review of the literature","volume":"5","author":"Alhaddad","year":"2012 -","journal-title":"Gastrointest Cancer Res."}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jscr\/article-pdf\/2020\/7\/rjaa203\/33553680\/rjaa203.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jscr\/article-pdf\/2020\/7\/rjaa203\/33553680\/rjaa203.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,31]],"date-time":"2020-07-31T14:32:07Z","timestamp":1596205927000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjaa203\/5872073"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,1]]},"references-count":7,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,7,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjaa203","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2020,7]]},"published":{"date-parts":[[2020,7,1]]},"article-number":"rjaa203"}}