{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:54:13Z","timestamp":1782604453695,"version":"3.54.5"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2020,10,9]],"date-time":"2020-10-09T00:00:00Z","timestamp":1602201600000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,10,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>Angiotensin-converting enzyme (ACE) inhibitors are the leading cause of drug-induced angioedema, being the face, tongue, lips and upper airway the most affected ones. We describe a case of a 32-year-old white female with angioedema of small intestine after 1\u00a0month of perindopril therapy. The patient presented severe abdominal pain, nausea and vomiting. Laboratory analyses revealed mild leukocytosis and abdominal computed tomography (CT) showed unspecific findings, including segmental jejunal wall thickening without obstruction and ascites. Regarding the clinical findings, similar to an acute abdomen with no clear cause, the patient underwent an emergency laparoscopy that excluded other pathological features. The symptoms recurred 1\u00a0month after and the CT scan revealed the same pattern. Perindopril was stopped and the patient improved, concluding that ACE inhibitor-induced visceral angioedema was responsible for this clinical presentation.<\/jats:p>","DOI":"10.1093\/jscr\/rjaa348","type":"journal-article","created":{"date-parts":[[2020,8,5]],"date-time":"2020-08-05T19:14:26Z","timestamp":1596654866000},"source":"Crossref","is-referenced-by-count":14,"title":["ACE inhibitor-induced small bowel angioedema, mimicking an acute abdomen"],"prefix":"10.1093","volume":"2020","author":[{"given":"Rafaela","family":"Parreira","sequence":"first","affiliation":[{"name":"General Surgery Department, Hospital do Divino Esp\u00edrito Santo, EPE, Ponta Delgada, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Amaral","sequence":"additional","affiliation":[{"name":"Imagiology Department, Hospital do Divino Esp\u00edrito Santo, EPE, Ponta Delgada, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu\u00eds","family":"Amaral","sequence":"additional","affiliation":[{"name":"General Surgery Department, Hospital do Divino Esp\u00edrito Santo, EPE, Ponta Delgada, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"El\u00f3i","sequence":"additional","affiliation":[{"name":"General Surgery Department, Hospital do Divino Esp\u00edrito Santo, EPE, Ponta Delgada, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria In\u00eas","family":"Leite","sequence":"additional","affiliation":[{"name":"General Surgery Department, Hospital do Divino Esp\u00edrito Santo, EPE, Ponta Delgada, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armando","family":"Medeiros","sequence":"additional","affiliation":[{"name":"General Surgery Department, Hospital do Divino Esp\u00edrito Santo, EPE, Ponta Delgada, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,10,9]]},"reference":[{"key":"2020122810394114900_ref1","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/j.jaip.2017.02.018","article-title":"Epidemiology of ACE inhibitor angioedema utilizing a large electronic health record","volume":"5","author":"Banerji","year":"2017","journal-title":"J Allergy Clin Immunol Pract"},{"key":"2020122810394114900_ref2","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.jemermed.2015.01.016","article-title":"Angiotensin-converting enzyme inhibitor\u2013induced angioedema of the small bowel\u2014a surgical abdomen mimic","volume":"48","author":"Bloom","year":"2015","journal-title":"J Emerg Med"},{"key":"2020122810394114900_ref3","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2019-230865","article-title":"An unusual presentation of ACE inhibitor-induced visceral 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