{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:56:02Z","timestamp":1753876562458,"version":"3.41.2"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2020,10,31]],"date-time":"2020-10-31T00:00:00Z","timestamp":1604102400000},"content-version":"vor","delay-in-days":30,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The rarity of male breast cancer continues to limit its study despite increasing incidence rates, particularly within the past decade [Speirs V, Shaaban AM. The rising incidence of male breast cancer. Breast Cancer Res Treat 2009;115:429\u201330]. Although this trend appears to be substantially documented, male patients with breast cancer have been and continue to be excluded from landmark breast cancer trials. Currently, there are no standardized breast cancer screening protocols in place for men, including those with pathogenic BRCA mutations. As a result, men with breast cancer typically present at a later stage, and on average, 8\u201310\u00a0years later than females [Ruddy KJ, Winer EP. Male breast cancer: risk factors, biology, diagnosis, treatment, and survivorship. Ann Oncol 2013;24:1434\u201343]. As the incidence of disease continues to rise, the need for algorithmic standardization with regards to screening, diagnosing, treating and managing male breast cancer has become imperative. We report the case of a 71-year-old male who presented with spontaneous bloody nipple discharge and was found to have bilateral ductal carcinoma in situ.<\/jats:p>","DOI":"10.1093\/jscr\/rjaa399","type":"journal-article","created":{"date-parts":[[2020,9,7]],"date-time":"2020-09-07T03:11:22Z","timestamp":1599448282000},"source":"Crossref","is-referenced-by-count":0,"title":["A spontaneous unveiling of bilateral DCIS in an elderly male"],"prefix":"10.1093","volume":"2020","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7401-5286","authenticated-orcid":false,"given":"Tessa","family":"Meyer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Borgen","sequence":"additional","affiliation":[{"name":"Department of Surgery, Maimonides Medical Center, Brooklyn, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristen","family":"Rojas","sequence":"additional","affiliation":[{"name":"Department of Surgery, Maimonides Medical Center, Brooklyn, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,10,31]]},"reference":[{"key":"2020103110105312400_ref1","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1007\/s10549-008-0053-y","article-title":"The rising incidence of male breast cancer","volume":"115","author":"Speirs","year":"2009","journal-title":"Breast Cancer Res Treat"},{"key":"2020103110105312400_ref2","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/S0140-6736(06)68226-3","article-title":"Male breast cancer","volume":"367","author":"Fentiman","year":"2006","journal-title":"Lancet"},{"key":"2020103110105312400_ref3","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1093\/annonc\/mdt025","article-title":"Male breast cancer: risk factors, biology, diagnosis, treatment, and survivorship","volume":"24","author":"Ruddy","year":"2013","journal-title":"Ann Oncol"},{"key":"2020103110105312400_ref4","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s10549-006-9356-z","article-title":"Male breast cancer: a review of clinical management","volume":"103","author":"Agrawal","year":"2007","journal-title":"Breast Cancer Res Treat"},{"key":"2020103110105312400_ref5","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1007\/s10549-011-1856-9","article-title":"A comparative biomarker study of 514 matched cases of male and female breast cancer reveals gender-specific biological differences","volume":"133","author":"Shaaban","year":"2012","journal-title":"Breast Cancer Res Treat"},{"key":"2020103110105312400_ref6","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.ejso.2005.09.013","article-title":"Steroid hormone receptor expression in male breast cancer","volume":"32","author":"Murphy","year":"2006","journal-title":"Eur J Surg Oncol"},{"key":"2020103110105312400_ref7","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1200\/JCO.2017.76.8861","article-title":"Molecular characterization and mortality from breast cancer in men","volume":"36","author":"Suleiman","year":"2018","journal-title":"J Clin Oncol"},{"key":"2020103110105312400_ref8","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1001\/jamaoncol.2015.2510","article-title":"Breast cancer mortality after a diagnosis of ductal carcinoma in situ","volume":"1","author":"Narod","year":"2015","journal-title":"JAMA Oncol"},{"key":"2020103110105312400_ref9","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1186\/bcr2930","article-title":"Male breast carcinoma: increased awareness needed","volume":"13","author":"White","year":"2011","journal-title":"Breast Cancer Res"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jscr\/article-pdf\/2020\/10\/rjaa399\/34069077\/rjaa399.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jscr\/article-pdf\/2020\/10\/rjaa399\/34069077\/rjaa399.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,31]],"date-time":"2020-10-31T14:11:00Z","timestamp":1604153460000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjaa399\/5944221"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,1]]},"references-count":9,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2020,10,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjaa399","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2020,10]]},"published":{"date-parts":[[2020,10,1]]},"article-number":"rjaa399"}}