{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T04:40:50Z","timestamp":1768711250555,"version":"3.49.0"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2021,3,22]],"date-time":"2021-03-22T00:00:00Z","timestamp":1616371200000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The perinatal management of newborns with giant omphaloceles requires careful suspicion concerning \u2018unexpected\u2019 associated malformations. We describe a newborn with a combination of incomplete Pentalogy of Cantrell consisting of giant omphalocele, anterior congenital diaphragmatic hernia (CDH) and pericardial absence complicated by a hepatic rapidly involuting congenital hemangioma (RICH). A giant omphalocele was detected prenatally. Postnatally, staged closure of the omphalocele was planned. A mass of the liver was noted and (mis-)taken for a hematoma. In the further course, the baby developed cardiorespiratory insufficiency due to a central CDH which was excised. Subsequently, staged closure of the omphalocele became impossible. Specific workup revealed a mass in the left liver lobe. The mass was resected and the abdominal wall defect repaired. Histology confirmed the diagnosis of an RICH. The surgical treatment of newborns with giant omphaloceles requires a multidisciplinary neonatal support and an elaborate pediatric surgical armamentarium to cope with additional malformations.<\/jats:p>","DOI":"10.1093\/jscr\/rjab047","type":"journal-article","created":{"date-parts":[[2021,2,4]],"date-time":"2021-02-04T03:48:30Z","timestamp":1612410510000},"source":"Crossref","is-referenced-by-count":3,"title":["Rapidly involuting congenital hemangioma of the liver in a newborn with incomplete Pentalogy of Cantrell: description of a new association"],"prefix":"10.1093","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3868-9136","authenticated-orcid":false,"given":"Paolo","family":"Gasparella","sequence":"first","affiliation":[{"name":"Department of Paediatric and Adolescent Surgery, Medical University of Graz, Graz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georg","family":"Singer","sequence":"additional","affiliation":[{"name":"Department of Paediatric and Adolescent Surgery, Medical University of Graz, Graz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Arneitz","sequence":"additional","affiliation":[{"name":"Department of Paediatric and Adolescent Surgery, Medical University of Graz, Graz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Benesch","sequence":"additional","affiliation":[{"name":"Division of Paediatric Hematology-Oncology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erich","family":"Sorantin","sequence":"additional","affiliation":[{"name":"Division of Paediatric Radiology, Department of Radiology, Medical University of Graz, Graz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Kampelm\u00fchler","sequence":"additional","affiliation":[{"name":"Institute of Pathology, Medical University of Graz, Graz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Schemmer","sequence":"additional","affiliation":[{"name":"Division of General\/Visceral and Transplant Surgery, Medical University of Graz, Graz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Holger","family":"Till","sequence":"additional","affiliation":[{"name":"Department of Paediatric and Adolescent Surgery, Medical University of Graz, Graz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,3,22]]},"reference":[{"key":"2021070811372706100_ref1","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s10029-007-0264-x","article-title":"Delayed three-stage closure of giant omphalocele using pericard patch","volume":"12","author":"Saxena","year":"2008","journal-title":"Hernia"},{"key":"2021070811372706100_ref2","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1053\/j.sempedsurg.2019.04.006","article-title":"Pentalogy of Cantrell","volume":"28","author":"Williams","year":"2019","journal-title":"Semin Pediatr Surg"},{"key":"2021070811372706100_ref3","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1016\/j.jpedsurg.2007.07.047","article-title":"Fetal and neonatal hepatic tumors","volume":"42","author":"Isaacs","year":"2007","journal-title":"J Pediatr Surg"},{"key":"2021070811372706100_ref4","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpedsurg.2020.02.008","article-title":"Congenital hepatic hemangiomas: clinical, histologic, and genetic correlation","volume":"55","author":"Triana","year":"2020","journal-title":"J Pediatr Surg"},{"key":"2021070811372706100_ref5","first-page":"602","article-title":"A syndrome of congenital defects involving the abdominal wall, sternum, diaphragm, pericardium, and heart","volume":"107","author":"Cantrell","year":"1958","journal-title":"Surg Gynecol Obstet"},{"key":"2021070811372706100_ref6","article-title":"Complete and incomplete pentalogy of Cantrell","volume":"6","author":"Kylat","year":"2019","journal-title":"Children (Basel)"},{"key":"2021070811372706100_ref7","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1007\/s00247-017-3914-x","article-title":"Fetal anterior abdominal wall defects: prenatal imaging by magnetic resonance imaging","volume":"48","author":"Victoria","year":"2018","journal-title":"Pediatr Radiol"},{"key":"2021070811372706100_ref8","doi-asserted-by":"crossref","first-page":"289","DOI":"10.23736\/S0026-4946.17.05109-X","article-title":"Predictors of mortality in neonates with giant omphaloceles","volume":"70","author":"Saxena","year":"2018","journal-title":"Minerva 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