{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T17:58:40Z","timestamp":1781114320538,"version":"3.54.1"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2021,4,22]],"date-time":"2021-04-22T00:00:00Z","timestamp":1619049600000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Paragangliomas (PGs) are extremely rare multicentric neoplasms. Hereditary or familial PGs are associated with germline mutations in succinate dehydrogenase genes, seen in one-third of cases. Primary PGs of the thyroid are uncommon neuroendocrine neoplasms that account for 0.012% of all head and neck lesions. Although majority of these tumors are solitary, familial PGs are associated with synchronous tumors (carotid\/vagal). We report an interesting case of primary thyroid PG in a patient with a previous history of a right carotid body, right vagal PGs and positive familial history, confining the differential diagnosis to recurrent lesions, which is the most common occurrence or new primary or a metastatic lesion. However, long interval and surgical anatomy suggests the diagnosis to be a primary lesion. In conclusion, although these lesions present multicentrically present at varying intervals, their occurrence at anatomically distinct sites should raise the concern for a new primary PG.<\/jats:p>","DOI":"10.1093\/jscr\/rjab102","type":"journal-article","created":{"date-parts":[[2021,2,26]],"date-time":"2021-02-26T12:15:02Z","timestamp":1614341702000},"source":"Crossref","is-referenced-by-count":1,"title":["Thyroid paraganglioma in a patient with a history of carotid and vagal paraganglioma: metastatic or primary tumor?"],"prefix":"10.1093","volume":"2021","author":[{"given":"Natesh","family":"Yepuri","sequence":"first","affiliation":[{"name":"Department of Surgery, SUNY Upstate Medical University, Syracuse, NY 13210, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gautam R","family":"Vanga","sequence":"additional","affiliation":[{"name":"Department of Surgery, SUNY Upstate Medical University, Syracuse, NY 13210, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rana","family":"Naous","sequence":"additional","affiliation":[{"name":"Department of Pathology, SUNY Upstate Medical University, Syracuse, NY 13210, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudhakar","family":"Kinthala","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Robert Packer Hospital, Sayre, PA 18840, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,4,22]]},"reference":[{"key":"2021070811401153500_ref1","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1097\/00000478-198012000-00010","article-title":"Paraganglioma of the thyroid gland","volume":"4","author":"Buss","year":"1980","journal-title":"Am J Surg Pathol"},{"key":"2021070811401153500_ref2","first-page":"E20","article-title":"Malignant paraganglioma of the thyroid gland with synchronous bilateral carotid body tumors","volume":"92","author":"Mohyuddin","year":"2013","journal-title":"Ear Nose Throat J"},{"key":"2021070811401153500_ref3","first-page":"82","article-title":"Glomic (paraganglionic) tissue in the larynx and capsule of the thyroid gland","volume":"39","author":"Zak","year":"1972","journal-title":"Mt Sinai J Med"},{"key":"2021070811401153500_ref4","doi-asserted-by":"crossref","first-page":"19","DOI":"10.6061\/clinics\/2012(Sup01)05","article-title":"Head and neck paragangliomas: clinical and molecular genetic classification","volume":"67","author":"Offergeld","year":"2012","journal-title":"Clinics (Sao Paulo)"},{"key":"2021070811401153500_ref5","doi-asserted-by":"crossref","first-page":"e133","DOI":"10.1016\/j.amjmed.2016.11.030","article-title":"A rarity in a common disease: thyroid paraganglioma","volume":"130","author":"Sangtian","year":"2017","journal-title":"Am J 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Metab"},{"key":"2021070811401153500_ref9","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1016\/S1470-2045(09)70164-0","article-title":"An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis","volume":"10","author":"van Nederveen","year":"2009","journal-title":"Lancet Oncol"}],"container-title":["Journal of Surgical Case 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