{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T12:30:20Z","timestamp":1765369820711,"version":"3.41.2"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2021,5,27]],"date-time":"2021-05-27T00:00:00Z","timestamp":1622073600000},"content-version":"vor","delay-in-days":26,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We describe a case of mild lower urinary tract symptoms and microscopic hematuria in a 53-year-old-male with hypertension found to have urethral stricture disease suspicious for urothelial carcinoma. During the investigation, cystoscopy and biopsy demonstrated eosinophilic amyloid proteins consistent with primary localized urethral amyloidosis. No systemic evidence of amyloidosis was demonstrated. Following a trial of conservative management with serial dilatations, the patient elected to proceed with surgical management by anterior urethroplasty using an excision and primary anastomosis technique. The patient has done well with resolution of his symptoms and no further recurrence of urethral amyloid disease at ongoing follow up.<\/jats:p>","DOI":"10.1093\/jscr\/rjab201","type":"journal-article","created":{"date-parts":[[2021,4,27]],"date-time":"2021-04-27T19:15:21Z","timestamp":1619550921000},"source":"Crossref","is-referenced-by-count":1,"title":["Primary localized amyloidosis causing urethral stricture disease: a mimicker of urothelial carcinoma"],"prefix":"10.1093","volume":"2021","author":[{"given":"Jas","family":"Singh","sequence":"first","affiliation":[{"name":"Department of Surgery, Section of Urology, University of Manitoba, Winnipeg, Manitoba R3P 1Y4, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,5,27]]},"reference":[{"key":"2021070811441687100_ref1","doi-asserted-by":"crossref","first-page":"3519","DOI":"10.3892\/etm.2017.4983","article-title":"Benefits of urethroplasty for managing urethral amyloidosis: a case report","volume":"14","author":"Yao","year":"2017","journal-title":"Exp Ther Med"},{"key":"2021070811441687100_ref2","doi-asserted-by":"crossref","DOI":"10.1186\/1757-1626-2-160","article-title":"Localized amyloidosis presenting with a penile mass: a case report","volume":"2","author":"Lim","year":"2009","journal-title":"Cases J"},{"key":"2021070811441687100_ref3","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.4065\/75.12.1264","article-title":"Primary localized amyloidosis of the urinary bladder: a case series of 31 patients","volume":"75","author":"Tirzaman","year":"2000","journal-title":"Mayo Clin Proc"},{"key":"2021070811441687100_ref4","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/j.1442-2042.1996.tb00506.x","article-title":"A case of primary localized amyloidosis of the penile urethra","volume":"3","author":"Sakuma","year":"1996","journal-title":"Int J Urol"},{"key":"2021070811441687100_ref5","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1259\/bjr\/52539691","article-title":"Primary localized amyloidosis manifested as supraclavicular and mediastinal lymphadenopathy","volume":"80","author":"Yong","year":"2007","journal-title":"Br J Radiol"},{"key":"2021070811441687100_ref6","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1056\/NEJM199709253371306","article-title":"The systemic amyloidoses","volume":"337","author":"Falk","year":"1997","journal-title":"N Engl J Med"},{"key":"2021070811441687100_ref7","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/S0002-9343(97)89487-9","article-title":"Treatment of 100 patients with primary amyloidosis: a randomized trial of melphalan, prednisone, and colchicine versus colchicine only","volume":"100","author":"Skinner","year":"1996","journal-title":"Am J Med"},{"key":"2021070811441687100_ref8","doi-asserted-by":"crossref","first-page":"484","DOI":"10.2169\/internalmedicine.44.484","article-title":"High-dose melphalan followed by autologous stem cell support in primary systemic AL amyloidosis with multiple organ involvement","volume":"44","author":"Shimojima","year":"2005","journal-title":"Intern Med"},{"key":"2021070811441687100_ref9","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1080\/003655902762467675","article-title":"A case of amyloid of the urethra and review of this rare diagnosis, its natural history and management, with reference to the literature","volume":"36","author":"Crook","year":"2002","journal-title":"Scand J Urol Nephrol"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jscr\/article-pdf\/2021\/5\/rjab201\/38276091\/rjab201.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jscr\/article-pdf\/2021\/5\/rjab201\/38276091\/rjab201.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,8]],"date-time":"2021-07-08T20:34:17Z","timestamp":1625776457000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjab201\/6285835"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,1]]},"references-count":9,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,5,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjab201","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2021,5]]},"published":{"date-parts":[[2021,5,1]]},"article-number":"rjab201"}}