{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T20:31:53Z","timestamp":1780345913949,"version":"3.54.1"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2021,5,27]],"date-time":"2021-05-27T00:00:00Z","timestamp":1622073600000},"content-version":"vor","delay-in-days":26,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Endometrial carcinoma is one of the most common gynaecologic malignancies in the western society. Treatment of recurrent disease became more refined, with the study of molecular and hormonal receptors playing a central role. A 76-year-old caucasian woman presented to the emergency department with growing tiredness, and melaena. Past medical history included an endometrioid adenocarcinoma. The patient had undergone a hysterectomy with bilateral salpingo-oophorectomy with pelvic and paraaortic lymphadenectomy and was disease-free for 2\u00a0years. The endoscopy revealed an ulcerated lesion involving the second and third portions of the duodenum. Histopathologic examination confirmed a poorly differentiated adenocarcinoma of endometrial origin. She started palliative chemotherapy, remaining with adequate symptomatic control. Endometrial cancer recurrence typically occurs locally. The liver is the intra-abdominal organ most commonly involved. There are scarce reports of duodenal metastasis of malignancies originated in distant organs. The duodenum remains an uncommon metastization site and is rarely associated with endometrial cancer.<\/jats:p>","DOI":"10.1093\/jscr\/rjab209","type":"journal-article","created":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T19:10:03Z","timestamp":1619809803000},"source":"Crossref","is-referenced-by-count":3,"title":["Duodenal recurrence of endometrial carcinoma: report of a rare metastatic site"],"prefix":"10.1093","volume":"2021","author":[{"given":"Jo\u00e3o L","family":"Pinheiro","sequence":"first","affiliation":[{"name":"General Surgery Department, Centro Hospitalar Tondela-Viseu, Viseu, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marisa","family":"Marques","sequence":"additional","affiliation":[{"name":"General Surgery Department, Centro Hospitalar Tondela-Viseu, Viseu, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Daniel","sequence":"additional","affiliation":[{"name":"Hepatobiliary and Pancreatic Department, Centro Hospitalar Tondela-Viseu, Viseu, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Pereira","sequence":"additional","affiliation":[{"name":"Hepatobiliary and Pancreatic Department, Centro Hospitalar Tondela-Viseu, Viseu, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Casimiro","sequence":"additional","affiliation":[{"name":"General Surgery Department, Centro Hospitalar Tondela-Viseu, Viseu, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,5,27]]},"reference":[{"key":"2021070811442186300_ref1","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1056\/NEJMra1514010","article-title":"Endometrial cancer","volume":"383","author":"Lu","year":"2020","journal-title":"N Engl J Med"},{"key":"2021070811442186300_ref2","doi-asserted-by":"crossref","first-page":"525","DOI":"10.2217\/fon-2020-0017","article-title":"Clinicopathological study of organ metastasis in endometrial cancer","volume":"16","author":"Mao","year":"2020","journal-title":"Future Oncol"},{"key":"2021070811442186300_ref3","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/s43046-020-00052-2","article-title":"Systemic recurrence of endometrial cancer more than 10 years after hysterectomy: a report of two cases and a brief review of the literature","volume":"32","author":"Muratori","year":"2020","journal-title":"J Egypt Natl Canc Inst"},{"key":"2021070811442186300_ref4","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1002\/ijgo.12612","article-title":"Cancer of the corpus uteri","volume":"143","author":"Amant","year":"2018","journal-title":"Int J Gynecol Obstet"},{"key":"2021070811442186300_ref5","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1102\/1470-7330.2013.0011","article-title":"Typical and atypical metastatic sites of recurrent endometrial carcinoma","volume":"13","author":"Kurra","year":"2013","journal-title":"Cancer Imaging"},{"key":"2021070811442186300_ref6","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1080\/14737140.2018.1491311","article-title":"Management strategies for recurrent endometrial cancer","volume":"18","author":"Connor","year":"2018","journal-title":"Expert Rev Anticancer Ther"},{"key":"2021070811442186300_ref7","doi-asserted-by":"crossref","first-page":"2907","DOI":"10.1002\/ccr3.3288","article-title":"Diagnostic benefit of cytological and histopathological examinations for recurrent vaginal cancer metastasizing to the duodenum: a case report","volume":"8","author":"Sonoda","year":"2020","journal-title":"Clin Case Reports"},{"key":"2021070811442186300_ref8","doi-asserted-by":"crossref","first-page":"648","DOI":"10.4103\/0973-1482.137675","article-title":"Metastatic tumors in the duodenum: a report of two cases","volume":"11","author":"Iwamuro","year":"2015","journal-title":"J Cancer Res Ther"},{"key":"2021070811442186300_ref9","first-page":"201","article-title":"Duodenal metastasis: an uncommon cause of occult small intestinal bleeding","volume":"62","author":"Loualidi","year":"2004","journal-title":"Neth J Med"},{"key":"2021070811442186300_ref10","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1097\/PGP.0b013e31821ac6c3","article-title":"Immunoexpression of PAX 8 in endometrial cancer: relation to high-grade carcinoma and p53","volume":"30","author":"Brunner","year":"2011","journal-title":"Int J Gynecol Pathol"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jscr\/article-pdf\/2021\/5\/rjab209\/38276131\/rjab209.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jscr\/article-pdf\/2021\/5\/rjab209\/38276131\/rjab209.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,8]],"date-time":"2021-07-08T20:34:31Z","timestamp":1625776471000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjab209\/6285841"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,1]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,5,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjab209","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,5]]},"published":{"date-parts":[[2021,5,1]]},"article-number":"rjab209"}}