{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T04:59:57Z","timestamp":1782190797804,"version":"3.54.5"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2021,7,23]],"date-time":"2021-07-23T00:00:00Z","timestamp":1626998400000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The parasite Entamoeba histolytica, the causal agent of amebiasis, is considered a worldwide emergent disease and still represents an important cause of death in Mexico. Here, we describe a clinical case, involving an inflammatory response to both Coronavirus Infectious Disease 2019 (COVID-19) and intestinal amebiasis 54-year-old, COVID-positive Mexican gentleman was admitted to surgery following 6 days of hematochezia. An exploratory laparotomy and colonoscopy revealed multiple fibrous and amebic ulcerations (5\u201310\u00a0cm in diameter), with necrotic tissue predominantly localized in the sigmoid, descending and ascending colon. We discuss the pathophysiological interplay of both COVID-19 and intestinal amebiasis with the aim of highlighting a potentially novel aggravating mechanism in surgical patients suffering from colonic perforation in the setting of abdominal sepsis.<\/jats:p>","DOI":"10.1093\/jscr\/rjab301","type":"journal-article","created":{"date-parts":[[2021,6,22]],"date-time":"2021-06-22T19:12:15Z","timestamp":1624389135000},"source":"Crossref","is-referenced-by-count":5,"title":["Fatal attraction: intestinal amebiasis and COVID-19 as risk factors for colonic perforation"],"prefix":"10.1093","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9523-7769","authenticated-orcid":false,"given":"Jorge Alberto","family":"Dorantes","sequence":"first","affiliation":[{"name":"International Program of Medicine, Universidad Aut\u00f3noma de Guadalajara, Zapopan, Jalisco, M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Octavio","family":"L\u00f3pez-Becerril","sequence":"additional","affiliation":[{"name":"Departamento de Cirug\u00eda, Hospital General de Tijuana, Tijuana, BC, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6508-9657","authenticated-orcid":false,"given":"Maria G","family":"Zavala-Cerna","sequence":"additional","affiliation":[{"name":"Immunology Research Laboratory, Universidad Autonoma de Guadalajara, Zapopan, Jalisco, M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,7,23]]},"reference":[{"key":"2021072317023505900_ref1","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/j.meegid.2009.06.008","article-title":"Reassessment of the epidemiology of amebiasis: state of the art","volume":"9","author":"Xim\u00e9nez","year":"2009","journal-title":"Infect Genet Evol"},{"key":"2021072317023505900_ref2","volume-title":"The World health report : 1998 : 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