{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T05:48:36Z","timestamp":1794030516851,"version":"4.8.0"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2021,7,23]],"date-time":"2021-07-23T00:00:00Z","timestamp":1626998400000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Parathyroid lipoadenoma is a very rare cause of primary hyperparathyroidism. Preoperative imaging techniques often fail to detect such lesions, and even during surgery they can be misinterpreted just as fat tissue. A 62-year-old woman clinically monitored for primary hyperparathyroidism, with hypertension and a left nephrectomy for hydrouretheronephrosis caused by recurrent kidney stones. A neck ultrasound showed a nodule consistent with left parathyroid of 9\u00a0\u00d7\u00a05\u00a0mm, which was not confirmed on single-photon-emission computed tomography\/computed tomography (CT) scan. On surgery, a voluminous lesion with adipose appearance and texture was removed. Frozen sections and intraoperative parathyroid hormone (PTH) confirmed such lesion to be a parathyroid lipoadenoma. Parathyroid lipoadenomas are difficult to localize preoperatively. Sometimes they can be seen by ultrasound scan as hyperechoich lesion, but scintigraphy and CT often fail to identify them. Only the awareness of such lesions and the use of intraoperative PTH can avoid unnecessary extensive cervical exploration.<\/jats:p>","DOI":"10.1093\/jscr\/rjab308","type":"journal-article","created":{"date-parts":[[2021,7,15]],"date-time":"2021-07-15T11:12:06Z","timestamp":1626347526000},"source":"Crossref","is-referenced-by-count":7,"title":["Atypical primary hyperparathyroidism due to parathyroid lipoadenoma: a case report"],"prefix":"10.1093","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4055-8485","authenticated-orcid":false,"given":"Francesco","family":"Cammarata","sequence":"first","affiliation":[{"name":"Department of General Surgery, Luigi Sacco University Hospital, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Al\u2019ona","family":"Yakushkina","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Ospedale di Saronno, Saronno VA, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Pennacchi","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Luigi Sacco University Hospital, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Carsana","sequence":"additional","affiliation":[{"name":"Department of Pathology, Luigi Sacco University Hospital, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Zerbi","sequence":"additional","affiliation":[{"name":"Department of Pathology, Luigi Sacco University Hospital, Milan, Italy"},{"name":"Department of Biomedical and Clinical Sciences Luigi Sacco, University of Milan, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulio","family":"Montecamozzo","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Luigi Sacco University Hospital, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piergiorgio","family":"Danelli","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Luigi Sacco University Hospital, Milan, Italy"},{"name":"Department of Biomedical and Clinical Sciences Luigi Sacco, University of Milan, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,7,23]]},"reference":[{"key":"2021072318293224300_ref1","volume-title":"Robbins Basic Pathology","author":"Kumar","year":"2013"},{"key":"2021072318293224300_ref2","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1007\/s12022-015-9404-5","article-title":"Parathyroid lipoadenoma: a clinic-pathological diagnosis and possible trap for the unawake pathologist","volume":"27","author":"Hyrcza","year":"2016","journal-title":"Endocr Pathol"},{"key":"2021072318293224300_ref3","doi-asserted-by":"crossref","DOI":"10.1007\/s12022-020-09616-3","article-title":"Lipoadenoma of the parathyroid gland: characterization of an institutional series spanning 28 years.","volume":"31","author":"Juhlin","year":"2020","journal-title":"Endocr Pathol"},{"key":"2021072318293224300_ref4","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1097\/PAS.0b013e31817a8ef7","article-title":"Parathyroid lipodenomas and lipohyperplasias: clinicopathologic correlations","volume":"32","author":"Seethala","year":"2008","journal-title":"Am J Surg Pathol"},{"key":"2021072318293224300_ref5","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1001\/archotol.132.12.1391","article-title":"Pathology quiz case 2. Parathyroid lipoadenoma","volume":"132","author":"Seethala","year":"2006","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"2021072318293224300_ref6","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1177\/014556131209101009","article-title":"Lipohyperplasia of the parathyroid glands","volume":"91","author":"Carter","year":"2012","journal-title":"Ear Nose Throat J"},{"key":"2021072318293224300_ref7","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1016\/j.anl.2018.05.001","article-title":"A rare cause of primary hyperparathyroidism: parathyroid lipoadenoma","volume":"45","author":"\u00d6zden","year":"2018","journal-title":"Auris Nasus Larynx"},{"key":"2021072318293224300_ref8","doi-asserted-by":"crossref","first-page":"131","DOI":"10.4158\/EP.12.2.131","article-title":"Parathyroid lipoadenomas: a rare cause of primary hyperparathyroidism","volume":"12","author":"Chow","year":"2006","journal-title":"Endocr Pract"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jscr\/article-pdf\/2021\/7\/rjab308\/39278133\/rjab308.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jscr\/article-pdf\/2021\/7\/rjab308\/39278133\/rjab308.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,23]],"date-time":"2021-07-23T18:29:45Z","timestamp":1627064985000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjab308\/6325682"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,1]]},"references-count":8,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,7,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjab308","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,7]]},"published":{"date-parts":[[2021,7,1]]},"article-number":"rjab308"}}