{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T08:55:11Z","timestamp":1771232111273,"version":"3.50.1"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"vor","delay-in-days":31,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Thyroid hyalinizing trabecular adenoma (HTA) is a rare and borderline tumor of follicular origin. It is characterized by a trabecular growth pattern and marked intratrabecular hyalinization. Excessively elevated thyroglobulin levels have not been reported previously in cases without bilateral lung metastases. Here, we present a case of a 54-year-old woman with chronic thyroiditis with a 50-mm tumor in the left lobe of the thyroid gland, which was observed on ultrasonography. Her thyroglobulin level was found to be elevated at 684\u00a0ng\/ml. Since fine needle aspiration cytology could not exclude possible malignancy, she underwent thyroid lobectomy; the final diagnosis was thyroid HTA. Two weeks after resection, her thyroglobulin level showed negative conversion. To our knowledge, this is the first report of a patient with a thyroid HTA exhibiting a thyroglobulin level as high as that for a patient with hyalinizing trabecular carcinoma.<\/jats:p>","DOI":"10.1093\/jscr\/rjab324","type":"journal-article","created":{"date-parts":[[2021,7,6]],"date-time":"2021-07-06T11:12:44Z","timestamp":1625569964000},"source":"Crossref","is-referenced-by-count":2,"title":["Thyroid hyalinizing trabecular adenoma with a high thyroglobulin level: a case report"],"prefix":"10.1093","volume":"2021","author":[{"given":"Hirofumi","family":"Katano","sequence":"first","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Nihon University Hospital, 1-6 Kandasurugadai, Chiyoda-ku, Tokyo 101-8309, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisashi","family":"Hasegawa","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Nihon University Hospital, 1-6 Kandasurugadai, Chiyoda-ku, Tokyo 101-8309, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroumi","family":"Matsuzaki","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Nihon University Hospital, 1-6 Kandasurugadai, Chiyoda-ku, Tokyo 101-8309, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Oshima","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Nihon University Hospital, 1-6 Kandasurugadai, Chiyoda-ku, Tokyo 101-8309, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyan","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Pathology, Nihon University School of Medicine, 1-6 Kandasurugadai, Chiyoda-ku, Tokyo 101-8309, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,7,31]]},"reference":[{"key":"2021080122401432100_ref1","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1097\/00000478-198708000-00001","article-title":"Hyalinizing trabecular adenoma of the thyroid gland","volume":"11","author":"Carney","year":"1987","journal-title":"Am J Surg Pathol"},{"key":"2021080122401432100_ref2","volume-title":"Pathology and Genetics of Tumours of Endocrine Organs. 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