{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T09:55:58Z","timestamp":1788947758317,"version":"build-2803163510"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2021,10,16]],"date-time":"2021-10-16T00:00:00Z","timestamp":1634342400000},"content-version":"vor","delay-in-days":15,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Segmental arterial mediolysis (SAM) is a nonatherosclerotic, noninflammatory and nonimmune arteriopathy of unknown aetiology. We present the case of a 43-year-old male who presented to the emergency department with abdominal pain. A computed tomography of abdomen and pelvis showed a narrow, hypodense superior mesenteric artery after the origin, raising the possibility of thrombus or vasculitis. He was commenced on rivaroxaban and steroids. He subsequently presented with an acute abdomen in a collapsed state. Repeat imaging of his abdomen and pelvis revealed an ischaemic ileal segment and caecum. He required an emergency laparotomy with resection of the ischaemic segment and formation of a double-barrelled stoma. SAM is an important diagnosis for clinicians and radiologists to be aware of, given the risks of life-threatening haemorrhage and acute organ ischaemia. This is a commonly overlooked cause of abdominal pain, where an early diagnosis with lifestyle modifications may prevent disease progression and subsequent development of life-threatening complications.<\/jats:p>","DOI":"10.1093\/jscr\/rjab370","type":"journal-article","created":{"date-parts":[[2021,8,9]],"date-time":"2021-08-09T11:18:18Z","timestamp":1628507898000},"source":"Crossref","is-referenced-by-count":4,"title":["Segmental arterial mediolysis: a rare cause of an acute abdomen"],"prefix":"10.1093","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8983-7231","authenticated-orcid":false,"given":"Czara A","family":"Kennedy","sequence":"first","affiliation":[{"name":"Department of General and Colorectal Surgery, Midland Regional Hospital Mullingar, Mullingar, Co. Westmeath, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Desmond P","family":"Toomey","sequence":"additional","affiliation":[{"name":"Department of General and Colorectal Surgery, Midland Regional Hospital Mullingar, Mullingar, Co. Westmeath, Ireland"},{"name":"Department of General and Colorectal Surgery, Mater Misericordiae University Hospital, Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,10,16]]},"reference":[{"key":"2021101620031794700_ref1","first-page":"23","article-title":"Segmental mediolytic arteritis: a clinical pathologic study","volume":"35","author":"Slavin","year":"1976","journal-title":"Lab Investig"},{"key":"2021101620031794700_ref2","first-page":"287","article-title":"Segmental arterial mediolysis: a precursor to fibromuscular dysplasia?","volume":"8","author":"Slavin","year":"1995","journal-title":"Mod Pathol"},{"key":"2021101620031794700_ref3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13000-017-0664-x","article-title":"Spontaneous isolated dissection of the superior mesenteric artery and aneurysm formation resulting from segmental arterial mediolysis: a case report","volume":"12","author":"Akuzawa","year":"2017","journal-title":"Diagn Pathol"},{"key":"2021101620031794700_ref4","doi-asserted-by":"publisher","DOI":"10.1177\/1708538120982696","article-title":"Ileocolic arterial aneurysm associated with segmental arterial mediolysis: a case report","author":"Honma","year":"2020","journal-title":"Vascular"},{"key":"2021101620031794700_ref5","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1177\/1358863X19873410","article-title":"Segmental arterial mediolysis (SAM): systematic review and analysis of 143 cases","volume":"24","author":"Skeik","year":"2019","journal-title":"Vasc Med"},{"key":"2021101620031794700_ref6","doi-asserted-by":"crossref","first-page":"e234576","DOI":"10.1136\/bcr-2020-234576","article-title":"Segmental arterial mediolysis: a commonly overlooked aetiology of acute abdominal pain","volume":"13","author":"Roy","year":"2020","journal-title":"BMJ Case Rep CP"},{"key":"2021101620031794700_ref7","doi-asserted-by":"crossref","first-page":"899","DOI":"10.2214\/AJR.17.18309","article-title":"Segmental arterial mediolysis: abdominal imaging of and disease course in 111 patients","volume":"210","author":"Naidu","year":"2018","journal-title":"Am J Roentgenol"},{"key":"2021101620031794700_ref8","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.2214\/AJR.05.0281","article-title":"Segmental arterial mediolysis: CTA findings at presentation and follow-up","volume":"187","author":"Michael","year":"2006","journal-title":"Am J Roentgenol"},{"key":"2021101620031794700_ref9","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.1016\/j.jvir.2011.07.001","article-title":"Segmental arterial mediolysis: clinical and imaging features at presentation and during follow-up","volume":"22","author":"Kalva","year":"2011","journal-title":"J Vasc Interv Radiol"},{"key":"2021101620031794700_ref10","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1007\/s00261-016-0887-4","article-title":"Imaging and clinical findings in segmental arterial mediolysis (SAM)","volume":"42","author":"Alhalabi","year":"2017","journal-title":"Abdominal Radiol"},{"key":"2021101620031794700_ref11","first-page":"173","article-title":"Segmental arterial mediolysis: an unusual case mistaken to be a strangulated hernia","volume":"116","author":"Japikse","year":"2017","journal-title":"WMJ"},{"key":"2021101620031794700_ref12","article-title":"Segmental arterial mediolysis: an under-recognized cause of chronic abdominal pain","volume":"7","author":"Chatterjee","year":"2020","journal-title":"Eur J Case Rep Intern Med"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jscr\/article-pdf\/2021\/10\/rjab370\/40669759\/rjab370.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jscr\/article-pdf\/2021\/10\/rjab370\/40669759\/rjab370.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,20]],"date-time":"2021-10-20T19:22:53Z","timestamp":1634757773000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjab370\/6398547"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,1]]},"references-count":12,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021,10,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjab370","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,10]]},"published":{"date-parts":[[2021,10,1]]},"article-number":"rjab370"}}