{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:05:50Z","timestamp":1753877150291,"version":"3.41.2"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2021,9,28]],"date-time":"2021-09-28T00:00:00Z","timestamp":1632787200000},"content-version":"vor","delay-in-days":27,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Lung carcinoma management secondary to chronic lymphocytic leukemia could be quite challenging. We report a case of a 60-year-old male with several co-morbidities, who presented with shortness of breath and persistent cough. A chest imaging showed a right pleural effusion and complete white-out of the right chest cavity. A computed tomography scan revealed consolidation of the right upper lobe with a 6-cm lesion in hilum with complete occlusion of right lobe bronchus. The patient underwent a video-assisted thoracoscopic surgery, drainage of pleural effusion and pleural and lung biopsy. Talc pleurodesis as well as a flexible bronchoscopy of the endobronchial lesion was performed. Histopathological examination showed a small B-cell lymphoma of the right pleura and an invasive non-small cell carcinoma of the right lung. Dual neoplasms are challenging in terms of diagnosing, and they usually require a multidisciplinary team for the right treatment strategy, including surgery and chemotherapy.<\/jats:p>","DOI":"10.1093\/jscr\/rjab412","type":"journal-article","created":{"date-parts":[[2021,9,8]],"date-time":"2021-09-08T11:19:00Z","timestamp":1631099940000},"source":"Crossref","is-referenced-by-count":0,"title":["Small lymphocytic lymphoma and lung malignancy coincidence in a male patient: a case report and literature review"],"prefix":"10.1093","volume":"2021","author":[{"given":"Christos D","family":"Kakos","sequence":"first","affiliation":[{"name":"Surgery Working Group, Society of Junior Doctors, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgios","family":"Geropoulos","sequence":"additional","affiliation":[{"name":"Surgery Working Group, Society of Junior Doctors, Athens, Greece"},{"name":"University College London Hospitals NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioannis","family":"Loufopoulos","sequence":"additional","affiliation":[{"name":"University College London Hospitals NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eirini","family":"Martzivanou","sequence":"additional","affiliation":[{"name":"Surgery Working Group, Society of Junior Doctors, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Nicolae","sequence":"additional","affiliation":[{"name":"University College London Hospitals NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reena","family":"Khiroya","sequence":"additional","affiliation":[{"name":"University College London Hospitals NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikolaos","family":"Panagiotopoulos","sequence":"additional","affiliation":[{"name":"University College London Hospitals NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sofoklis","family":"Mitsos","sequence":"additional","affiliation":[{"name":"University College London Hospitals NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,9,27]]},"reference":[{"volume-title":"SEER Cancer Statistics Review, 1975-2017","year":"2020","author":"Howlader","key":"2021092821114368900_ref1"},{"key":"2021092821114368900_ref2","first-page":"313","article-title":"Splenic leukemia with carcinoma","volume":"29","author":"Whipham","year":"1878","journal-title":"Trans Pathol Soc London"},{"key":"2021092821114368900_ref3","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1002\/1097-0142(196502)18:2<145::AID-CNCR2820180204>3.0.CO;2-A","article-title":"Leukemia and cancer in the same patient","volume":"18","author":"Gunz","year":"1965","journal-title":"Cancer"},{"key":"2021092821114368900_ref4","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1600-0609.1969.tb01810.x","article-title":"Increased incidence of neoplasia in association with chronic lymphocytic leukaemia","volume":"6","author":"Hyman","year":"1969","journal-title":"Scand J Haematol"},{"key":"2021092821114368900_ref5","first-page":"378","article-title":"Second neoplasms with chronic lymphocytic leukemia","volume":"76","author":"Moayeri","year":"1976","journal-title":"N Y State J Med"},{"key":"2021092821114368900_ref6","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1002\/(SICI)1097-0142(19991101)86:9<1720::AID-CNCR13>3.0.CO;2-X","article-title":"The clinical course of lung carcinoma in patients with chronic lymphocytic leukemia","volume":"86","author":"Parekh","year":"1999","journal-title":"Cancer"},{"key":"2021092821114368900_ref7","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1002\/ijc.22672","article-title":"Risk of second cancer after chronic lymphocytic leukemia","volume":"121","author":"Schollkopf","year":"2007","journal-title":"Int J Cancer"},{"key":"2021092821114368900_ref8","first-page":"337","article-title":"Subsequent cancer in patients with chronic lymphocytic leukemia-a possible immunologic mechanism","volume":"61","author":"Greene","year":"1978","journal-title":"J Natl Cancer Inst"},{"key":"2021092821114368900_ref9","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/S0140-6736(80)90622-4","article-title":"Extra chromosome 12 in chronic lymphocytic leukaemia","volume":"1","author":"Gahrton","year":"1980","journal-title":"Lancet"},{"key":"2021092821114368900_ref10","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S0065-230X(08)60179-7","article-title":"Immunodepression and malignancy","volume":"22","author":"Stutman","year":"1975","journal-title":"Adv Cancer Res"},{"key":"2021092821114368900_ref11","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1093\/oxfordjournals.aje.a115387","article-title":"Familial cancer history and chronic lymphocytic leukemia. A case-control study","volume":"130","author":"Linet","year":"1989","journal-title":"Am J Epidemiol"},{"key":"2021092821114368900_ref12","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1159\/000328790","article-title":"Lymph node collision tumor of non-small cell lung carcinoma and chronic lymphocytic leukemia","volume":"34","author":"Grenader","year":"2011","journal-title":"Onkologie"},{"key":"2021092821114368900_ref13","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1097\/00000421-199506000-00003","article-title":"Synchronous primary hepatic lymphoma and epidermoid lung carcinoma treated with chemotherapy and surgery","volume":"18","author":"Graziano","year":"1995","journal-title":"Am J Clin Oncol"},{"key":"2021092821114368900_ref14","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1378\/chest.75.2.174","article-title":"Bronchogenic carcinoma in chronic lymphocytic leukemia","volume":"75","author":"Amamoo","year":"1979","journal-title":"Chest"},{"key":"2021092821114368900_ref15","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1182\/blood.V12.9.788.788","article-title":"Leukemia or lymphoma and coexistent primary malignant lesions: a review of the literature and a study of 120 cases","volume":"12","author":"Moertel","year":"1957","journal-title":"Blood"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jscr\/article-pdf\/2021\/9\/rjab412\/40444180\/rjab412.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jscr\/article-pdf\/2021\/9\/rjab412\/40444180\/rjab412.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,28]],"date-time":"2021-09-28T21:45:22Z","timestamp":1632865522000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjab412\/6374327"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,1]]},"references-count":15,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021,9,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjab412","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2021,9]]},"published":{"date-parts":[[2021,9,1]]},"article-number":"rjab412"}}