{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T20:57:56Z","timestamp":1765486676766,"version":"3.41.2"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Perforation is a known complication of endoscopic resection and has been managed with endoscopic defect closure, antibiotics and close observation. Closure of duodenal perforations are more challenging due to the presence of gastric and pancreaticobiliary secretions. The use of endoluminal vacuum therapy (EVT) to divert flow and aid closure is increasingly prevalent and may avoid high-risk surgery. We describe the use of endoluminal vacuum closure to salvage an iatrogenic duodenal perforation in a 57-year-old male who underwent an endoscopic mucosal resection of a 35-mm polypoid lesion on the posterior wall of the second portion of the duodenum. The endoluminal wound vac successfully controlled leakage and allowed defect closure. EVT is an emerging technique that can effectively manage complicated injuries throughout the GI tract and may allow enhanced recovery by avoiding surgical salvage and its associated morbidity and mortality.<\/jats:p>","DOI":"10.1093\/jscr\/rjab479","type":"journal-article","created":{"date-parts":[[2021,10,30]],"date-time":"2021-10-30T11:08:04Z","timestamp":1635592084000},"source":"Crossref","is-referenced-by-count":4,"title":["Endoluminal vacuum closure of a duodenal perforation"],"prefix":"10.1093","volume":"2021","author":[{"given":"Danielle","family":"Abbitt","sequence":"first","affiliation":[{"name":"Department of GI, Trauma and Endocrine Surgery, The University of Colorado Anschutz Medical Campus, Aurora, CO, USA"},{"name":"Department of Surgery, Rocky Mountain Regional VA Medical Center, Aurora, CO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abigail L","family":"Barnes","sequence":"additional","affiliation":[{"name":"Department of Gynecology, St. Joseph Hospital, Denver, CO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hazem T","family":"Hammad","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Medicine, The University of Colorado Anschutz Medical Campus, Aurora, CO, USA"},{"name":"Department of Gastroenterology, Rocky Mountain Regional VA Medical Center, Aurora, CO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R Matthew","family":"Reveille","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Medicine, The University of Colorado Anschutz Medical Campus, Aurora, CO, USA"},{"name":"Department of Gastroenterology, Rocky Mountain Regional VA Medical Center, Aurora, CO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1449-8255","authenticated-orcid":false,"given":"Edward L","family":"Jones","sequence":"additional","affiliation":[{"name":"Department of GI, Trauma and Endocrine Surgery, The University of Colorado Anschutz Medical Campus, Aurora, CO, USA"},{"name":"Department of Surgery, Rocky Mountain Regional VA Medical Center, Aurora, CO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,11,5]]},"reference":[{"key":"2021110621394497200_ref1","first-page":"129","article-title":"Clinical outcome of endoscopic resection for nonampullary duodenal tumors","volume":"47","author":"Nonaka","year":"2015","journal-title":"Endoscopy"},{"key":"2021110621394497200_ref2","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1055\/a-1442-2395","article-title":"Endoscopic management of superficial nonampullary duodenal tumors: European Society of Gastrointestinal Endoscopy (ESGE) Guideline","volume":"53","author":"Vanbiervliet","year":"2021","journal-title":"Endoscopy"},{"key":"2021110621394497200_ref3","first-page":"121","article-title":"The endoscopic treatment of iatrogenic 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leakage after esophagectomy: a comparative retrospective study","volume":"27","author":"Schniewind","year":"2013","journal-title":"Surg Endosc"},{"key":"2021110621394497200_ref13","doi-asserted-by":"crossref","first-page":"E1424","DOI":"10.1055\/a-0972-9660","article-title":"Endoscopic negative pressure therapy (ENPT) for duodenal leakage - novel repair technique using open-pore film (OFD) and polyurethane-foam drainages (OPD)","volume":"7","author":"Loske","year":"2019","journal-title":"Endosc Int Open"},{"key":"2021110621394497200_ref14","doi-asserted-by":"crossref","first-page":"5581","DOI":"10.21873\/anticanres.12892","article-title":"Surgical endoscopic vacuum-assisted closure therapy (EVAC) in treating anastomotic leakages after major resective surgery of esophageal and gastric cancer","volume":"38","author":"Virgilio","year":"2018","journal-title":"Anticancer Res"},{"key":"2021110621394497200_ref15","doi-asserted-by":"crossref","DOI":"10.3390\/jcm10112346","article-title":"Endoscopic vacuum therapy in patients with transmural defects of the upper gastrointestinal tract: a systematic review with meta-analysis","volume":"10","author":"Jung","year":"2021","journal-title":"J Clin Med"}],"container-title":["Journal of Surgical Case 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