{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T15:55:36Z","timestamp":1771257336379,"version":"3.50.1"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2021,11,12]],"date-time":"2021-11-12T00:00:00Z","timestamp":1636675200000},"content-version":"vor","delay-in-days":11,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>There is little research on the role of urethrectomy during cystectomy in patients with micropapillary bladder cancer (MPBC). We present two cases of MPBC cystectomy and suggest that urethrectomy be performed concurrently as a preventive measure. The first case involved a woman who had a mixed solid and papillary bladder tumour. An anterior pelvic exenteration was performed as well as a total urethrectomy. The T4a micropapillary variant tumour was confirmed by pathology. The second case involved a man with T1 MPBC who was treated with a BCG induction course. A recurrent muscle-invasive MPBC was discovered during follow-up. During the radical cystoprostatectomy, the urethra was spared. T2 MPBC was discovered through pathology. He had a urethrectomy 6\u00a0months later due to urethral bleeding, and the pathology revealed micropapillary cancer of the urethra.<\/jats:p>","DOI":"10.1093\/jscr\/rjab501","type":"journal-article","created":{"date-parts":[[2021,10,21]],"date-time":"2021-10-21T11:09:52Z","timestamp":1634814592000},"source":"Crossref","is-referenced-by-count":2,"title":["Micropapillary bladder cancer: an added indication to prophylactic urethrectomy"],"prefix":"10.1093","volume":"2021","author":[{"given":"Vahid","family":"Mehrnoush","sequence":"first","affiliation":[{"name":"Department of Urology, Northern Ontario School of Medicine, TBRHSC, 980 Oliver Road, Thunder Bay, Ontario, P7B 6V4, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asmaa","family":"Ismail","sequence":"additional","affiliation":[{"name":"Department of Urology, Northern Ontario School of Medicine, TBRHSC, 980 Oliver Road, Thunder Bay, Ontario, P7B 6V4, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Zakaria","sequence":"additional","affiliation":[{"name":"Department of Urology, Northern Ontario School of Medicine, TBRHSC, 980 Oliver Road, Thunder Bay, Ontario, P7B 6V4, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hazem","family":"Elmansy","sequence":"additional","affiliation":[{"name":"Department of Urology, Northern Ontario School of Medicine, TBRHSC, 980 Oliver Road, Thunder Bay, Ontario, P7B 6V4, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walid","family":"Shahrour","sequence":"additional","affiliation":[{"name":"Department of Urology, Northern Ontario School of Medicine, TBRHSC, 980 Oliver Road, Thunder Bay, Ontario, P7B 6V4, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Owen","family":"Prowse","sequence":"additional","affiliation":[{"name":"Department of Urology, Northern Ontario School of Medicine, TBRHSC, 980 Oliver Road, Thunder Bay, Ontario, P7B 6V4, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1484-1332","authenticated-orcid":false,"given":"Ahmed","family":"Kotb","sequence":"additional","affiliation":[{"name":"Department of Urology, Northern Ontario School of Medicine, TBRHSC, 980 Oliver Road, Thunder Bay, Ontario, P7B 6V4, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,11,11]]},"reference":[{"key":"2021111719322967700_ref1","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1016\/j.urolonc.2014.01.020","article-title":"Micropapillary bladder cancer: current treatment patterns and review of the literature","volume":"32","author":"Willis","year":"2014","journal-title":"Urol Oncol"},{"key":"2021111719322967700_ref2","doi-asserted-by":"crossref","first-page":"415","DOI":"10.3233\/BLC-160066","article-title":"Micropapillary bladder cancer: insights from the National Cancer Database","volume":"2","author":"Sui","year":"2016","journal-title":"Bladder Cancer"},{"key":"2021111719322967700_ref3","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1016\/j.juro.2014.09.092","article-title":"Clinical outcomes of cT1 micropapillary bladder cancer","volume":"193","author":"Willis","year":"2015","journal-title":"J Urol"},{"key":"2021111719322967700_ref4","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1093\/jjco\/hyaa168","article-title":"Significance of prophylactic urethrectomy at the time of radical cystectomy for bladder cancer","volume":"51","author":"Hakozaki","year":"2021","journal-title":"Jpn J Clin Oncol"},{"key":"2021111719322967700_ref5","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1016\/j.juro.2008.07.039","article-title":"Urologic Diseases in America Project. Urethrectomy followingcystectomy for bladder cancer in men: practice patterns and impact on survival","volume":"180","author":"Nelles","year":"2008","journal-title":"J Urol"},{"key":"2021111719322967700_ref6","doi-asserted-by":"crossref","first-page":"354.e19","DOI":"10.1016\/j.urolonc.2019.01.026","article-title":"Outcomes of nonmetastatic micropapillary variant upper tract urothelial carcinoma","volume":"37","author":"Duplisea","year":"2019","journal-title":"Urol Oncol"},{"key":"2021111719322967700_ref7","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.clgc.2020.10.002","article-title":"Response to neoadjuvant chemotherapy and survival in micropapillary urothelial carcinoma: data from a tertiary referral center and the surveillance, epidemiology, and end results (SEER) program","volume":"19","author":"Diamantopoulos","year":"2021","journal-title":"Clin Genitourin Cancer"},{"key":"2021111719322967700_ref8","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.anuro.2006.03.001","article-title":"Ur\u00e9trectomie: techniques et indications [Indications and techniques in urethrectomy]","volume":"40","author":"Van Poppel","year":"2006","journal-title":"Ann Urol (Paris)"},{"key":"2021111719322967700_ref9","doi-asserted-by":"crossref","first-page":"230","DOI":"10.5489\/cuaj.5902","article-title":"Canadian Urological Association guideline: muscle-invasive bladder cancer","volume":"13","author":"Kulkarni","year":"2019","journal-title":"Can Urol Assoc J"},{"key":"2021111719322967700_ref10","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1093\/annonc\/mdz296","article-title":"EAU-ESMO consensus statements on the management of advanced and variant bladder cancer-an international collaborative multi-stakeholder effort: under the auspices of the EAU and ESMO guidelines committees","volume":"30","author":"Horwich","year":"2019","journal-title":"Ann Oncol"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2021\/11\/rjab501\/41132097\/rjab501.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2021\/11\/rjab501\/41132097\/rjab501.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,17]],"date-time":"2021-11-17T19:34:59Z","timestamp":1637177699000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjab501\/6425592"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,1]]},"references-count":10,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,11,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjab501","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,11]]},"published":{"date-parts":[[2021,11,1]]},"article-number":"rjab501"}}