{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:06:02Z","timestamp":1753877162483,"version":"3.41.2"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"vor","delay-in-days":30,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Leiomyosarcoma (LMS) is a common form of soft tissue sarcoma. Primary colonic LMS is an extremely rare entity, comprising 1\u20132% of gastrointestinal malignancies. Primary mesenchymal sarcomas of the gastrointestinal system are rare and constitute just 0.1\u20133% of all gastrointestinal tumours. LMS is the most common variant of such tumours and represents just 0.12% of colorectal malignancies.<\/jats:p>\n               <jats:p>We present a case of a 65-year-old female, who presented to the emergency department with 3 days history of obstipation and generalized abdominal pain. Radiology (X-ray and ultrasound) indicated a large pelvic mass compressing the sigmoid colon and its surrounding structures.<\/jats:p>\n               <jats:p>Histopathological analysis indicated a primary LMS of the sigmoid colon. Diagnosis is established mostly postoperatively after histopathological evaluation. Prognosis and treatment modalities for this aggressive malignancy remain insufficient. LMS is relatively impervious to chemotherapy\/radiotherapy. Our patient was treated by surgical excision of the tumour and referred postoperatively for adjuvant chemotherapy.<\/jats:p>","DOI":"10.1093\/jscr\/rjab515","type":"journal-article","created":{"date-parts":[[2021,10,26]],"date-time":"2021-10-26T19:13:54Z","timestamp":1635275634000},"source":"Crossref","is-referenced-by-count":2,"title":["Spindle Cell Sarcoma (SCS); a case of primary leiomyosarcoma (LMS) of the sigmoid colon presented as intestinal obstruction"],"prefix":"10.1093","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0292-0287","authenticated-orcid":false,"given":"Omar","family":"Al Laham","sequence":"first","affiliation":[{"name":"Department of Surgery, Al-Mouwasat University Hospital, Mazzah, Damascus, Syria"},{"name":"Department of Surgery, Al Assad University Hospital, Kafar Sousah, Damascus, Syria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3816-7175","authenticated-orcid":false,"given":"Reham","family":"Albrijawy","sequence":"additional","affiliation":[{"name":"Department of Surgery, Al-Mouwasat University Hospital, Mazzah, Damascus, Syria"},{"name":"Department of Surgery, Al Assad University Hospital, Kafar Sousah, Damascus, Syria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fareed","family":"Atia","sequence":"additional","affiliation":[{"name":"Department of Surgery, Al-Mouwasat University Hospital, Mazzah, Damascus, Syria"},{"name":"Department of Surgery, Al Assad University Hospital, Kafar Sousah, Damascus, Syria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jack","family":"Shaheen","sequence":"additional","affiliation":[{"name":"Department of Surgery, Al-Mouwasat University Hospital, Mazzah, Damascus, Syria"},{"name":"Department of Surgery, Al Assad University Hospital, Kafar Sousah, Damascus, Syria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hani","family":"AlTabbakh","sequence":"additional","affiliation":[{"name":"Department of Surgery, Al-Mouwasat University Hospital, Mazzah, Damascus, Syria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,11,30]]},"reference":[{"key":"2021120505405520300_ref1","doi-asserted-by":"crossref","first-page":"314","DOI":"10.5152\/tjg.2014.4010","article-title":"Primary mesenchymal tumors of the colon: a report of three cases","volume":"25","author":"Yaren","year":"2014","journal-title":"Turk J Gastroenterol"},{"key":"2021120505405520300_ref2","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1007\/BF00941809","article-title":"Leiomyosarcoma of the colon presenting as acute suppurative peritonitis","volume":"27","author":"Iwasa","year":"1997","journal-title":"Surg 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