{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:06:45Z","timestamp":1753877205432,"version":"3.41.2"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2022,1,23]],"date-time":"2022-01-23T00:00:00Z","timestamp":1642896000000},"content-version":"vor","delay-in-days":22,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Sphenoid mucoceles, although rare, should be considered in patients with headache, visual disorders and eye paralysis. Due to close relationships with the orbit and neuromeningeal structures, early recognition is vital. We report the case of a patient who presented with bilateral abducens nerve palsies. At surgery, she was found to have a mucopyocele; this was drained and she required prolonged intravenous antibiotic therapy due to ongoing symptoms and persistent dural enhancement on imaging. A lesion of sufficient size in the clival area has the potential to cause bilateral abducens nerve palsies, though we believe this is the first time it has been described in relation to a sphenoid mucocele. Imaging plays a crucial role in diagnosis, and prompt surgical intervention is essential to avoid serious and permanent complications. The multi-disciplinary team approach is vital\u2014these cases requiring input from ophthalmology, ear nose and throat, microbiology, radiology, neurology and neurosurgery.<\/jats:p>","DOI":"10.1093\/jscr\/rjab607","type":"journal-article","created":{"date-parts":[[2021,12,15]],"date-time":"2021-12-15T04:14:39Z","timestamp":1639541679000},"source":"Crossref","is-referenced-by-count":0,"title":["Sphenoid mucopyocele causing bilateral sixth nerve palsy"],"prefix":"10.1093","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6977-4325","authenticated-orcid":false,"given":"Mairead","family":"Kelly","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liisa","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parag","family":"Patel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Weller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajeev","family":"Advani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raj","family":"Lakhani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,1,21]]},"reference":[{"key":"2022012321210873900_ref1","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.otohns.2005.04.023","article-title":"Isolated sphenoid sinus disease: etiology and management","volume":"133","author":"Friedman","year":"2005","journal-title":"Otolaryngol Head Neck Surg"},{"key":"2022012321210873900_ref2","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1038\/eye.1998.167","article-title":"ENT pathology and diplopia","volume":"12","author":"Muneer","year":"1998","journal-title":"Eye"},{"key":"2022012321210873900_ref3","doi-asserted-by":"crossref","first-page":"e87","DOI":"10.1016\/j.jfo.2012.08.011","article-title":"Mucoc\u00e8le sph\u00e9no\u00efdale bilat\u00e9rale r\u00e9v\u00e9l\u00e9e par une paralysie du nerf abducens: \u00e0 propos d'un cas [Bilateral sphenoid sinus mucocele presenting as abducens nerve palsy: case report]","volume":"36","author":"Alami","year":"2013","journal-title":"J Fr Ophtalmol"},{"key":"2022012321210873900_ref4","first-page":"366","article-title":"Review of a series with abducens nerve palsy","volume":"18","author":"Ayberk","year":"2008","journal-title":"Turk 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base","volume":"30","author":"Naito","year":"2020","journal-title":"Case Rep Otolaryngol"},{"key":"2022012321210873900_ref9","doi-asserted-by":"crossref","first-page":"515","DOI":"10.4103\/0301-4738.99863","article-title":"Spheniodal mucocele causing bilateral optic neuropathy and ophthalmoplegia","volume":"62","author":"Selvakumar","year":"2014","journal-title":"Indian J Ophthalmol"},{"key":"2022012321210873900_ref10","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1038\/sj.eye.6701581","article-title":"Sphenoid sinus mucocoele presenting with optic neuropathy and abducens palsy: a late complication of radiotherapy to the head and neck","volume":"19","author":"Lin","year":"2005","journal-title":"Eye"},{"key":"2022012321210873900_ref11","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.nrl.2019.05.005","article-title":"Paresia del nervio abducens bilateral aislada secundaria a met\u00e1stasis en clivus de adenocarcinoma de pr\u00f3stata inadvertida en resonancia magn\u00e9tica","volume":"35","author":"May\u00e0-Casalprim","year":"2020","journal-title":"Neurologia"},{"key":"2022012321210873900_ref12","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.clineuro.2003.07.002","article-title":"Isolated bilateral sixth nerve palsy secondary to metastatic carcinoma: a case report with a review of the literature","volume":"106","author":"Kocak","year":"2003","journal-title":"Clin Neurol Neurosurg"},{"key":"2022012321210873900_ref13","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1017\/S0022215109991551","article-title":"Sphenoid sinus mucocele: 10 cases and literature review","volume":"124","author":"Soon","year":"2010","journal-title":"J Laryngol Otol"}],"container-title":["Journal of Surgical Case 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