{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T07:35:09Z","timestamp":1767771309190,"version":"3.41.2"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2022,1,26]],"date-time":"2022-01-26T00:00:00Z","timestamp":1643155200000},"content-version":"vor","delay-in-days":25,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Glomus tumors are rare and usually benign. The malignant form (glomangiosarcoma) comprises &amp;lt;1% of all glomus tumors. There are limited reports that describe glomus tumors in the nasal cavity. However, to the best of our knowledge, glomangiosarcoma of the nasal cavity was never reported in humans. We report on the first case of nasal cavity glomangiosarcoma in a 59-year-old male who presented with a bleeding mass in his right nostril. We completely excised the lesion with a 0.7-mm free margin, and the histopathologic examination was consistent with glomangiosarcoma. A 6-month follow-up illustrated no evidence of recurrence or distant metastasis. Although it is rare, glomus tumors should be in the differential diagnosis of nasal cavity tumors. Histopathologic examination is essential for glomangiosarcoma diagnosis. Treatment requires complete excision with free margin, alongside careful clinical and radiological follow-up.<\/jats:p>","DOI":"10.1093\/jscr\/rjab641","type":"journal-article","created":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T20:11:07Z","timestamp":1640722267000},"source":"Crossref","is-referenced-by-count":1,"title":["A case of malignant glomus tumor (glomangiosarcoma) of the nasal cavity"],"prefix":"10.1093","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4551-6276","authenticated-orcid":false,"given":"Omar A","family":"Alhroub","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shimaa A","family":"Mahameed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad O","family":"Abdelhafez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asil","family":"Alhroub","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hani","family":"Hour","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nabil","family":"Hasasna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nazmi","family":"Kamal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,1,26]]},"reference":[{"journal-title":"Ear Nose Throat J","article-title":"Nasal septum glomus tumor: a rare cause of unilateral nasal obstruction","author":"Kilmpasanis","key":"2022012621415697800_ref1"},{"key":"2022012621415697800_ref2","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1111\/pin.12866","article-title":"Nasal glomus tumor: a rare nasal tumor with diffuse and strongly positive synaptophysin expression","volume":"69","author":"Meguro","year":"2019","journal-title":"Pathol Int"},{"key":"2022012621415697800_ref3","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.4065\/81.10.1337","article-title":"Extradigital glomus tumors: a 20-year experience","volume":"81","author":"Schiefer","year":"2006","journal-title":"Mayo Clin Proc"},{"key":"2022012621415697800_ref4","first-page":"e19256","article-title":"Extradigital glomus tumor mimics an intrinsic nerve tumor in a trauma patient: case report and literature review","volume":"13","author":"Ajala","year":"2021","journal-title":"Cureus"},{"key":"2022012621415697800_ref5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00000478-200101000-00001","article-title":"Atypical and malignant glomus tumors: analysis of 52 cases, with a proposal for the reclassification of glomus tumors","volume":"25","author":"Folpe","year":"2001","journal-title":"Am J Surg Pathol"},{"key":"2022012621415697800_ref6","doi-asserted-by":"crossref","first-page":"326","DOI":"10.4132\/KoreanJPathol.2010.44.3.326","article-title":"Glomus tumor of the sinonasal tract: two case reports and a review of literature","volume":"44","author":"Koh","year":"2010","journal-title":"Korean J Pathol"},{"key":"2022012621415697800_ref7","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.jcpa.2016.03.002","article-title":"Malignant glomus tumour (glomangiosarcoma) with additional neuroendocrine differentiation in a horse","volume":"154","author":"Peters","year":"2016","journal-title":"J Comp Pathol"},{"key":"2022012621415697800_ref8","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.21037\/atm-20-6998","article-title":"Glomus tumors associated with the bone and joints: a review of 91 cases","volume":"8","author":"Wang","year":"2020","journal-title":"Ann Transl Med"},{"key":"2022012621415697800_ref9","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1177\/1066896914567330","article-title":"Clinical and histopathological diagnosis of glomus tumor: an institutional experience of 138 cases","volume":"23","author":"Mravic","year":"2015","journal-title":"Int J Surg Pathol"},{"author":"Pathology Outlines","key":"2022012621415697800_ref10","article-title":"Glomus tumor"},{"key":"2022012621415697800_ref11","first-page":"46","article-title":"The immunophenotype of hemangiopericytomas and glomus tumors, with special reference to muscle protein expression: an immunohistochemical study and review of the literature","volume":"4","author":"Porter","year":"1991","journal-title":"Mod Pathol"},{"key":"2022012621415697800_ref12","doi-asserted-by":"crossref","first-page":"2867","DOI":"10.1002\/1097-0142(19950615)75:12<2867::AID-CNCR2820751212>3.0.CO;2-8","article-title":"Use of immunohistochemical procedures in diagnosing angiosarcoma. Evaluation of 98 cases","volume":"75","author":"Ohsawa","year":"1995","journal-title":"Cancer"},{"key":"2022012621415697800_ref13","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1097\/PAS.0b013e318206b67b","article-title":"ERG transcription factor as an immunohistochemical marker for vascular endothelial tumors and prostatic carcinoma","volume":"35","author":"Miettinen","year":"2011","journal-title":"Am J Surg Pathol"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2022\/1\/rjab641\/42275766\/rjab641.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2022\/1\/rjab641\/42275766\/rjab641.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,26]],"date-time":"2022-01-26T21:42:14Z","timestamp":1643233334000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjab641\/6515550"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,1]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjab641","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2022,1]]},"published":{"date-parts":[[2022,1,1]]},"article-number":"rjab641"}}