{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T12:44:18Z","timestamp":1785156258902,"version":"3.55.0"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2022,2,9]],"date-time":"2022-02-09T00:00:00Z","timestamp":1644364800000},"content-version":"vor","delay-in-days":8,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Neuroendocrine carcinomas (NECs) arising from the extrahepatic bile duct (EHBD) are extremely rare, and their preoperative diagnosis is difficult. A small number of resected cases of EHBD NECs has been reported, and their prognosis is usually poor. A 62-year-old man presented with obstructive jaundice and liver disease. Radiological imaging revealed wall thickness and stricture of the distal common bile duct (CBD); however, lymph node or distant metastasis was not detected. Adenocarcinoma was detected on biopsy, and surgery was performed with a preoperative diagnosis of cholangiocarcinoma of the distal CBD. Pathological examination revealed adenocarcinoma of the CBD mucosa (20%) and NEC of the CBD wall (80%). The final pathological diagnosis was small-cell NEC of the EHBD. His post-operative course was good, and there was no recurrence for 4\u00a0months after surgery. Herein, we report a case of resected EHBD NEC and a literature review.<\/jats:p>","DOI":"10.1093\/jscr\/rjac020","type":"journal-article","created":{"date-parts":[[2022,1,15]],"date-time":"2022-01-15T12:07:28Z","timestamp":1642248448000},"source":"Crossref","is-referenced-by-count":5,"title":["Case of resected small-cell neuroendocrine carcinoma of the extrahepatic bile duct"],"prefix":"10.1093","volume":"2022","author":[{"given":"Hiroaki","family":"Sugita","sequence":"first","affiliation":[{"name":"Department of Surgery, Fukui Prefectural Hospital, Fukui, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuya","family":"Maeda","sequence":"additional","affiliation":[{"name":"Department of Surgery, Fukui Prefectural Hospital, Fukui, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Nishikawa","sequence":"additional","affiliation":[{"name":"Department of Surgery, Fukui Prefectural Hospital, Fukui, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Doden","sequence":"additional","affiliation":[{"name":"Department of Surgery, Fukui Prefectural Hospital, Fukui, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuo","family":"Hashizume","sequence":"additional","affiliation":[{"name":"Department of Surgery, Fukui Prefectural Hospital, Fukui, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,2,9]]},"reference":[{"key":"2022021004544712700_ref1","doi-asserted-by":"crossref","first-page":"3063","DOI":"10.1200\/JCO.2007.15.4377","article-title":"One hundred years afte \u201ccarcinoid\u201d: epidemiology of and prognostic factors for neuroendocrine tumors in 35,825 cases in the United States","volume":"26","author":"Yao","year":"2008","journal-title":"J Clin 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carcinoma","volume":"96","author":"Terashima","year":"2012","journal-title":"Neuroendocrinology"},{"key":"2022021004544712700_ref12","doi-asserted-by":"crossref","first-page":"452","DOI":"10.3904\/kjim.2017.188","article-title":"Primary large cell neuroendocrine carcinoma of the common hepatic duct mimicking a Klatskin tumor","volume":"34","author":"Koo","year":"2019","journal-title":"Korean J Intern Med"}],"container-title":["Journal of Surgical Case 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