{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T06:45:01Z","timestamp":1769150701720,"version":"3.49.0"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2022,5,6]],"date-time":"2022-05-06T00:00:00Z","timestamp":1651795200000},"content-version":"vor","delay-in-days":5,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Epstein\u2013Barr virus-positive inflammatory follicular dendritic cell sarcoma is a variant of follicular dendritic cell neoplasm most often arising in the liver or spleen. Two histological patterns can be identified in this variant, namely a granulomatous and an eosinophil-rich one. We present the case of a 69-year-old woman with a splenic mass. After being removed, the mass was gray-whitish with an area of necrosis. Histology showed a diffuse distribution of epithelioid granulomas in a background of a dense lymphoplasmacytic infiltrate. Rare atypical cells EBV+ and CD21+ were present in the intergranulomatous areas. Differential diagnosis for the granulomatous type EBV+ inflammatory follicular dendritic cell sarcoma includes infection, sarcoidosis, inflammatory myofibroblastic tumor, T cell lymphoma and vasculitis. The origin of this neoplasm is the follicular dendritic cell, and, due to its similarities with a myofibroblast, differential diagnosis can be challenging. Immunohistochemistry for dendritic markers and in situ hybridization for EBER remain diagnostic keys.<\/jats:p>","DOI":"10.1093\/jscr\/rjac034","type":"journal-article","created":{"date-parts":[[2022,5,6]],"date-time":"2022-05-06T00:10:42Z","timestamp":1651795842000},"source":"Crossref","is-referenced-by-count":4,"title":["Granulomatous splenic mass with necrosis revealing an EBV-positive inflammatory follicular dendritic cell sarcoma"],"prefix":"10.1093","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9541-0202","authenticated-orcid":false,"given":"Irena Antonia","family":"Ungureanu","sequence":"first","affiliation":[{"name":"Department of Pathology, Ambroise-Par\u00e9 Hospital, AP-HP, Boulogne-Billancourt 92100, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renato Micelli","family":"Lupinacci","sequence":"additional","affiliation":[{"name":"EA4340-BECCOH Research Unit, Universit\u00e9 de Versailles SQY, Versailles 78000, France"},{"name":"Department of Digestive and Oncologic Surgery, Ambroise-Par\u00e9 Hospital, AP-HP, Boulogne-Billancourt 92100, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie","family":"Parrens","sequence":"additional","affiliation":[{"name":"Department of Pathology, CHU de Bordeaux, INSERM U1053, Universit\u00e9 de Bordeaux, Bordeaux 33000, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Fran\u00e7ois","family":"Emile","sequence":"additional","affiliation":[{"name":"Department of Pathology, Ambroise-Par\u00e9 Hospital, AP-HP, Boulogne-Billancourt 92100, France"},{"name":"EA4340-BECCOH Research Unit, Universit\u00e9 de Versailles SQY, Versailles 78000, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,5,5]]},"reference":[{"key":"2022050600051216000_ref1","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.4251\/wjgo.v11.i12.1231","article-title":"Inflammatory pseudotumor-like follicular dendritic cell sarcoma: a brief report of two cases","volume":"11","author":"Zhang","year":"2019","journal-title":"World J Gastrointest Oncol"},{"key":"2022050600051216000_ref2","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1097\/00000478-200106000-00003","article-title":"Inflammatory pseudotumor-like follicular dendritic cell tumor: a distinctive low-grade malignant intra-abdominal neoplasm with consistent Epstein-Barr virus association","volume":"25","author":"Cheuk","year":"2001","journal-title":"Am J Surg Pathol"},{"key":"2022050600051216000_ref3","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/s41241-017-0051-7","article-title":"Inflammatory 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