{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T22:39:29Z","timestamp":1781044769521,"version":"3.54.1"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2022,2,22]],"date-time":"2022-02-22T00:00:00Z","timestamp":1645488000000},"content-version":"vor","delay-in-days":21,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Renal cell carcinoma (RCC) most commonly metastasizes to the lung, adrenals, brain and pancreas, but metastasis to the stomach is uncommon. We present a 77-year-old male who underwent left nephrectomy 9 years previously for RCC with known metastatic disease to the lungs, diaphragm and stomach, and required multiple transfusions for acute blood loss anemia. A previous esophagogastroduodenoscopy revealed a large, friable, ulcerated mass at the gastric cardia. Biopsies of the mass demonstrated clear-cell carcinoma compatible with metastatic RCC. After multiple attempts at endoscopic, procedures and embolization were unsuccessful at controlling bleeding, the patient was treated with palliative total gastrectomy with Roux-en-Y gastric bypass. At discharge, the patient had been hemodynamically stable and tolerating a liquid diet. This case report highlights the presenting symptomology of RCC, explores the rarity of gastric metastases, and reviews current literature on management strategies for these patients.<\/jats:p>","DOI":"10.1093\/jscr\/rjac045","type":"journal-article","created":{"date-parts":[[2022,2,3]],"date-time":"2022-02-03T20:10:53Z","timestamp":1643919053000},"source":"Crossref","is-referenced-by-count":6,"title":["Metastatic renal cell carcinoma presenting as chronic bleeding from the stomach: a rare case report"],"prefix":"10.1093","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7554-231X","authenticated-orcid":false,"given":"Brandon","family":"Tapasak","sequence":"first","affiliation":[{"name":"University of Central Florida, College of Medicine, Orlando, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aron","family":"Mcguirt","sequence":"additional","affiliation":[{"name":"University of Central Florida, College of Medicine, Orlando, FL, USA"},{"name":"Bay Pines VA Healthcare System, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,2,22]]},"reference":[{"key":"2022030113303112000_ref1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3322\/caac.21654","article-title":"Cancer Statistics, 2021","volume":"71","author":"Siegel","year":"2021","journal-title":"CA Cancer J Clin"},{"key":"2022030113303112000_ref2","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2020.21869","article-title":"Evaluation of clear cell, papillary, and chromophobe renal cell carcinoma metastasis sites and association with survival","volume":"4","author":"Dudani","year":"2021","journal-title":"JAMA Netw Open"},{"key":"2022030113303112000_ref3","doi-asserted-by":"crossref","first-page":"178","DOI":"10.14740\/wjon1406","article-title":"Metastatic clear cell renal cell carcinoma: the great pretender and the great dilemma","volume":"12","author":"Maestroni","year":"2021","journal-title":"World J Oncol"},{"key":"2022030113303112000_ref4","doi-asserted-by":"crossref","first-page":"86","DOI":"10.9738\/INTSURG-D-13-00115.1","article-title":"Gastric metastasis from renal cell carcinoma with gastrointestinal bleeding: a case report and review of the literature","volume":"99","author":"Sakurai","year":"2014","journal-title":"Int Surg"},{"key":"2022030113303112000_ref5","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1159\/000514376","article-title":"Metastatic renal cell carcinoma presenting as gastrointestinal bleeding","volume":"15","author":"Hakim","year":"2021","journal-title":"Case Rep Gastroenterol"},{"key":"2022030113303112000_ref6","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1016\/j.dld.2020.08.025","article-title":"Upper gastrointestinal bleeding due to gastric metastasis of renal cell carcinoma","volume":"53","author":"Orosz","year":"2021","journal-title":"Dig Liver Dis"},{"key":"2022030113303112000_ref7","first-page":"57","article-title":"Renal cell carcinoma with metastases to the rectum and gastric body","volume":"33","author":"Bernshteyn","year":"2019","journal-title":"Proc (Bayl Univ Med Cent)"},{"key":"2022030113303112000_ref8","doi-asserted-by":"crossref","DOI":"10.1177\/1179547618775095","article-title":"Simultaneous gastric metastasis from renal cell carcinoma: a case report and literature review","volume":"11","author":"Arakawa","year":"2018","journal-title":"Clin Med Insights Case Rep"},{"key":"2022030113303112000_ref9","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1007\/s12029-010-9165-9","article-title":"Gastric metastasis in renal cell carcinoma: a case report and systematic review","volume":"42","author":"Eslick","year":"2011","journal-title":"J Gastrointest Cancer"},{"key":"2022030113303112000_ref10","doi-asserted-by":"crossref","first-page":"127","DOI":"10.4103\/0974-7796.68864","article-title":"Upper gastro-intestinal bleeding - 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