{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T14:41:49Z","timestamp":1778856109314,"version":"3.51.4"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T00:00:00Z","timestamp":1647302400000},"content-version":"vor","delay-in-days":14,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>A 41-year-old female presented with an 8-month history of right upper quadrant pain, exacerbated by ingestion of saturated fats. The patient was positive for antibodies to Coxsackievirus serotype B4, established by an investigation incited by an acute episode of pleurodynia 8\u00a0months before the current presentation. Imaging studies including a hepatobiliary iminodiacetic acid scan showed no gallbladder structural or functional abnormalities. Laboratory studies indicated pancreatic enzyme insufficiency associated with below-normal lipase and amylase levels. Patient symptomology was consistent with cholecystitis with positive Murphy\u2019s sign, so cholecystectomy was recommended. Post-surgery pathological report confirmed chronic acalculous cholecystitis. Patient demonstrated full recovery, indicated by return of normal pancreatic enzymes levels and resolution of abdominal pain.<\/jats:p>","DOI":"10.1093\/jscr\/rjac074","type":"journal-article","created":{"date-parts":[[2022,2,16]],"date-time":"2022-02-16T20:10:43Z","timestamp":1645042243000},"source":"Crossref","is-referenced-by-count":2,"title":["Case report: chronic acalculous cholecystitis preceded by Coxsackievirus B4 infection"],"prefix":"10.1093","volume":"2022","author":[{"given":"Connor E","family":"Fewel","sequence":"first","affiliation":[{"name":"Department of Microbiology, Immunology and Pharmacology School of Medicine, St. George's University, Grenada, West Indies"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua R","family":"Weiss","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Immunology and Pharmacology School of Medicine, St. George's University, Grenada, West Indies"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane C","family":"Harrington","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Immunology and Pharmacology School of Medicine, St. George's University, Grenada, West Indies"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,3,15]]},"reference":[{"key":"2022031517075313500_ref1","doi-asserted-by":"crossref","first-page":"riy031","DOI":"10.1093\/jscr\/rjy031","article-title":"Clinically diagnosed cholecystitis: a case series","volume":"2018","author":"Bridges","year":"2018","journal-title":"J Surg Case Rep"},{"key":"2022031517075313500_ref2","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/0002-9343(90)90094-T","article-title":"Clinical evaluation for gallstone disease: usefulness of symptoms and signs in diagnosis","volume":"89","author":"Diehl","year":"1990","journal-title":"Am J Med"},{"key":"2022031517075313500_ref3","volume-title":"Group B Coxsackie Virus","author":"Tariq","year":"2021"},{"key":"2022031517075313500_ref4","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1067\/msy.2001.116906","article-title":"The clinical diagnosis of chronic acalculous cholecystitis","volume":"130","author":"Chen","year":"2001","journal-title":"Surgery"},{"key":"2022031517075313500_ref5","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.gtc.2010.02.012","article-title":"Acute acalculous cholecystitis","volume":"39","author":"Barie","year":"2010","journal-title":"Gastroenterol Clin North Am"},{"key":"2022031517075313500_ref6","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1053\/jpsu.2002.29423","article-title":"Acute acalculous cholecystitis in children: diagnosis and treatment","volume":"37","author":"\u0130mamo\u011flu","year":"2002","journal-title":"J Pediatr Surg"},{"key":"2022031517075313500_ref7","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1016\/j.jhep.2020.08.020","article-title":"COVID-19 can mimic acute cholecystitis and is associated with the presence of viral RNA in the gallbladder wall","volume":"73","author":"Balaphas","year":"2020","journal-title":"J Hepatol"},{"key":"2022031517075313500_ref8","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.amsu.2020.11.031","article-title":"Post COVID 19 acute acalculous cholecystitis raising the possibility of underlying dysregulated immune response, a case report","volume":"60","author":"Alhassan","year":"2020","journal-title":"Ann Med Surg"},{"key":"2022031517075313500_ref9","first-page":"407182","article-title":"Acute Acalculous cholecystitis due to viral hepatitis a","volume":"2013","author":"Kaya","year":"2013","journal-title":"Case Rep Infect Dis"},{"key":"2022031517075313500_ref10","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1177\/0009922810363729","article-title":"Epstein Barr virus-associated acute acalculous cholecystitis: a rare occurrence but favorable outcome","volume":"49","author":"Arya","year":"2010","journal-title":"Clin Pediatr"},{"key":"2022031517075313500_ref11","doi-asserted-by":"crossref","first-page":"8229","DOI":"10.1128\/JVI.78.15.8229-8237.2004","article-title":"Progression or resolution of coxsackievirus B4-induced pancreatitis: a genomic analysis","volume":"78","author":"Ostrowski","year":"2004","journal-title":"J Virol"},{"key":"2022031517075313500_ref12","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1007\/s00431-003-1315-7","article-title":"Transient exocrine pancreatic insufficiency as a possible complication of an enterovirus infection","volume":"162","author":"Van Biervliet","year":"2003","journal-title":"Eur J Pediatr"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2022\/3\/rjac074\/42897969\/rjac074.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2022\/3\/rjac074\/42897969\/rjac074.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T17:13:38Z","timestamp":1647364418000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjac074\/6548708"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,1]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,3,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjac074","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,3]]},"published":{"date-parts":[[2022,3,1]]},"article-number":"rjac074"}}