{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T05:10:37Z","timestamp":1788412237841,"version":"build-2803163510"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T00:00:00Z","timestamp":1730937600000},"content-version":"vor","delay-in-days":6,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The incidence and prevalence of syphilis are rising worldwide. Rectal syphilis is a rare condition with few reported cases in the literature and therefore often missed from differential diagnosis of atypical anorectal ulceration. We report a case of a 64-year-old male who presented with change in the bowel habit and a palpable rectal mass on examination. Colonoscopy revealed a small, ulcerated lesion in the rectum. However, histopathological analysis and radiological assessments were inconclusive. A cutaneous ulceration prompted a repeat biopsy and staining for spirochaetes, which was diagnostic of syphilitic proctitis. He was successfully treated with first line antibiotics via the Genitourinary Medicine clinic. With its increasing incidence, syphilis should be considered as a potential diagnosis of atypical anorectal ulceration. A complete sexual history including relevant risk factors should be taken and a full clinical examination performed actively looking for signs and symptoms of disease.<\/jats:p>","DOI":"10.1093\/jscr\/rjac102","type":"journal-article","created":{"date-parts":[[2022,3,2]],"date-time":"2022-03-02T07:07:50Z","timestamp":1646204870000},"source":"Crossref","is-referenced-by-count":6,"title":["Diagnosis and management of rectal syphilis\u2014case report"],"prefix":"10.1093","volume":"2024","author":[{"given":"Zeeshan","family":"Afzal","sequence":"first","affiliation":[{"name":"Cambridge Colorectal Unit, Cambridge University Hospital NHS Foundation Trust , Cambridge,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Hussein","sequence":"additional","affiliation":[{"name":"Cambridge Colorectal Unit, Cambridge University Hospital NHS Foundation Trust , Cambridge,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"O\u2019Donovan","sequence":"additional","affiliation":[{"name":"Department of Histopathology & Cytology, Cambridge University Hospital NHS Foundation Trust , Cambridge,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Bowden","sequence":"additional","affiliation":[{"name":"Department of Radiology, Cambridge University Hospital NHS Foundation Trust , Cambridge,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard J","family":"Davies","sequence":"additional","affiliation":[{"name":"Cambridge Colorectal Unit, Cambridge University Hospital NHS Foundation Trust , Cambridge,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Buczacki","sequence":"additional","affiliation":[{"name":"Cambridge Colorectal Unit, Cambridge University Hospital NHS Foundation Trust , Cambridge,","place":["UK"]},{"name":"Nuffield Department of Surgical Sciences , University of Oxford, Headington, Oxford, OX3 7DQ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,11,6]]},"reference":[{"key":"2024110705534710100_ref1","author":"National Institute of Clinical Excellence (NICE) Syphilis NICE"},{"key":"2024110705534710100_ref2","volume-title":"Syphilis and Lymphograuloma Venerum: resurgent sexually transmitted infections in UK","author":"Health Protection Agency"},{"key":"2024110705534710100_ref3","author":"Public Health England"},{"key":"2024110705534710100_ref4","volume-title":"Sexually transmitted infections and screening for Chlamydia in England 2018"},{"key":"2024110705534710100_ref5","volume-title":"Centres for disease control and prevention"},{"key":"2024110705534710100_ref6","volume-title":"Sexually Transmitted Disease (STD), Syphilis-CDC Fact Sheet (Detailed)","author":"CDC Centres for Disease control and prevention"},{"key":"2024110705534710100_ref7","author":"NICE"},{"key":"2024110705534710100_ref8","volume-title":"When to Suspect. NICE","author":"National Institute of Clinical Excellence (NICE)"},{"key":"2024110705534710100_ref9","volume-title":"Management. NICE","author":"National Institute of Clinical Excellence (NICE)"},{"key":"2024110705534710100_ref10","volume-title":"Current Guideline","author":"British Association for Sexual Health and HIV"},{"key":"2024110705534710100_ref11","volume-title":"UK national guidelines on the management of syphilis 2015"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/11\/rjac102\/60455807\/rjac102.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/11\/rjac102\/60455807\/rjac102.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T00:53:53Z","timestamp":1730940833000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjac102\/7879561"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,1]]},"references-count":11,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2024,11,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjac102","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,11]]},"published":{"date-parts":[[2024,11,1]]},"article-number":"rjac102"}}