{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T06:48:20Z","timestamp":1769064500497,"version":"3.49.0"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2022,5,22]],"date-time":"2022-05-22T00:00:00Z","timestamp":1653177600000},"content-version":"vor","delay-in-days":21,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["F30CA236031"],"award-info":[{"award-number":["F30CA236031"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Meckel\u2019s diverticulum is a congenital anomaly leading to the formation of a true diverticulum in the distal small intestine. Though most are asymptomatic and discovered incidentally, Meckel\u2019s diverticuli can give rise to a wide range of symptoms. Rarely, this can be a malignancy, most commonly a carcinoid tumor. Other cancers have also been reported, with adenocarcinomas being particularly rare. Here, we report the case of a 62-year-old man presenting to the emergency room with vague gastrointestinal symptoms. Subsequent workup revealed a 3\u00a0cm mass in the distal jejunum\/proximal ileum, which was located within a previously undiagnosed Meckel\u2019s diverticulum. The mass was sent to pathology, who confirmed an adenocarcinoma arising from a small bowel diverticulum. This case serves as an important reminder of the malignant potential of a Meckel\u2019s diverticulum and adds to the ongoing discussion regarding whether prophylactic diverticulectomy should be recommended to patients with a known Meckel\u2019s diverticulum.<\/jats:p>","DOI":"10.1093\/jscr\/rjac128","type":"journal-article","created":{"date-parts":[[2022,3,14]],"date-time":"2022-03-14T20:12:30Z","timestamp":1647288750000},"source":"Crossref","is-referenced-by-count":7,"title":["Intestinal adenocarcinoma originating from an undiagnosed Meckel\u2019s diverticulum"],"prefix":"10.1093","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4355-6597","authenticated-orcid":false,"given":"Daniel R","family":"Principe","sequence":"first","affiliation":[{"name":"Department of Surgery, University of Illinois at Chicago, Chicago, IL, USA"},{"name":"Medical Scientist Training Program, University of Illinois College of Medicine, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Nesper","sequence":"additional","affiliation":[{"name":"Chicago Medical School at Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anastasia E","family":"Metropulos","sequence":"additional","affiliation":[{"name":"Northwestern University Feinberg School of Medicine, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Rubin","sequence":"additional","affiliation":[{"name":"University of Illinois Metropolitan Group Residency Program, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marin N","family":"Marinov","sequence":"additional","affiliation":[{"name":"Chicago Medical School at Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA"},{"name":"Department of Surgery, Advocate Medical Group Lutheran General Hospital, Park Ridge, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,5,22]]},"reference":[{"key":"2022052216361343400_ref1","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1177\/014107680609901011","article-title":"Meckel's diverticulum: a systematic review","volume":"99","author":"Sagar","year":"2006","journal-title":"J R Soc Med"},{"key":"2022052216361343400_ref2","volume-title":"Meckel Diverticulum","author":"An","year":"2022"},{"key":"2022052216361343400_ref3","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1097\/01.sla.0000154270.14308.5f","article-title":"Meckel diverticulum: the Mayo Clinic experience with 1476 patients (1950-2002)","volume":"241","author":"Park","year":"2005","journal-title":"Ann Surg"},{"key":"2022052216361343400_ref4","doi-asserted-by":"crossref","first-page":"81","DOI":"10.2214\/AJR.06.1257","article-title":"Imaging manifestations of Meckel\u2019s diverticulum","volume":"189","author":"Elsayes","year":"2007","journal-title":"AJR Am J Roentgenol"},{"key":"2022052216361343400_ref5","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.amsu.2019.05.017","article-title":"Malignant neoplasms of Meckel\u2019s diverticulum; an evidence based review","volume":"43","author":"Kabir","year":"2019","journal-title":"Ann Med Surg (Lond)"},{"key":"2022052216361343400_ref6","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1097\/SLA.0b013e3181ef488d","article-title":"Meckel's diverticulum--a high-risk region for malignancy in the ileum. Insights from a population-based epidemiological study and implications in surgical management","volume":"253","author":"Thirunavukarasu","year":"2011","journal-title":"Ann Surg"},{"key":"2022052216361343400_ref7","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1177\/2050640617752771","article-title":"Malignancy and Meckel's diverticulum: a systematic literature review and 14-year experience at a tertiary referral center","volume":"6","author":"Malderen","year":"2018","journal-title":"United Eur Gastroenterol J"},{"key":"2022052216361343400_ref8","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/S1072-7515(01)00817-1","article-title":"Meckel's diverticulum","volume":"192","author":"Yahchouchy","year":"2001","journal-title":"J Am Coll Surg"},{"key":"2022052216361343400_ref9","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.1016\/j.jpedsurg.2017.03.047","article-title":"Optimizing surgical resection of the bleeding Meckel diverticulum in children","volume":"52","author":"Robinson","year":"2017","journal-title":"J Pediatr Surg"},{"key":"2022052216361343400_ref10","first-page":"910","article-title":"Adenocarcinoma in Meckel's diverticulum: report of a case and review of 30 cases in the English and Japanese literature","volume":"87","author":"Kusumoto","year":"1992","journal-title":"Am J Gastroenterol"},{"key":"2022052216361343400_ref11","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/0002-9610(76)90043-X","article-title":"The natural history of Meckel's diverticulum and its relation to incidental removal. A study of 202 cases of diseased Meckel's diverticulum found in King County, Washington, over a fifteen year period","volume":"132","author":"Soltero","year":"1976","journal-title":"Am J Surg"},{"key":"2022052216361343400_ref12","first-page":"353","article-title":"Complications of Meckel\u2019s diverticula in adults","volume":"49","author":"Dumper","year":"2006","journal-title":"Can J Surg"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2022\/5\/rjac128\/43780652\/rjac128.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2022\/5\/rjac128\/43780652\/rjac128.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,22]],"date-time":"2022-05-22T16:36:33Z","timestamp":1653237393000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjac128\/6590379"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,1]]},"references-count":12,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjac128","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,5]]},"published":{"date-parts":[[2022,5,1]]},"article-number":"rjac128"}}