{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:06:26Z","timestamp":1753877186009,"version":"3.41.2"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2022,5,25]],"date-time":"2022-05-25T00:00:00Z","timestamp":1653436800000},"content-version":"vor","delay-in-days":24,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>In patients presenting with symptomatic bone metastases, the usual primary malignancies are breast, prostate, thyroid, lung and kidney. Pancreatic cancers are an uncommon cause of bone metastasis and, when they are, it is typically to the axial skeleton. We present the case of a 77-year-old woman who presented to our emergency department with right arm pain. Investigation demonstrated a metastatic lesion with impending pathological fracture. Further investigation found a necrotic pancreatic mass in the tail of the pancreas. Histopathology from the humeral metastasis was consistent with metastatic adenosquamous carcinoma of pancreatic origin. The humerus metastasis was successfully managed with an intramedullary nail. This case highlights an unusual presentation of pancreatic adenocarcinoma with humeral bone metastasis.<\/jats:p>","DOI":"10.1093\/jscr\/rjac157","type":"journal-article","created":{"date-parts":[[2022,3,25]],"date-time":"2022-03-25T04:15:26Z","timestamp":1648181726000},"source":"Crossref","is-referenced-by-count":0,"title":["Humeral metastases: an unusual presentation of pancreatic cancer"],"prefix":"10.1093","volume":"2022","author":[{"given":"Jonathan A","family":"McCafferty","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, Northeast Health Wangaratta , Wangaratta, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew D","family":"Free","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Northeast Health Wangaratta , Wangaratta, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel J","family":"De Villiers","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Northeast Health Wangaratta , Wangaratta, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prue P A","family":"Keith","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Northeast Health Wangaratta , Wangaratta, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,5,25]]},"reference":[{"key":"2022053116192846700_ref1","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1097\/00003086-198912000-00027","article-title":"Metastatic disease in long bones. A proposed scoring system for diagnosing impending pathologic fractures","volume":"249","author":"Mirels","year":"1989","journal-title":"Clin Orthop Relat Res"},{"volume-title":"Cancer data in Australia","year":"2021","author":"Australian Institute of Health and Welfare","key":"2022053116192846700_ref2"},{"key":"2022053116192846700_ref3","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.jss.2020.09.024","article-title":"Clinical and histological basis of adenosquamous carcinoma of the pancreas: a 30-year experience","volume":"259","author":"Moslim","year":"2021","journal-title":"J Surg Res"},{"key":"2022053116192846700_ref4","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.jss.2011.06.015","article-title":"415 patients with adenosquamous carcinoma of the pancreas: a population-based analysis of prognosis and survival","volume":"174","author":"Boyd","year":"2012","journal-title":"J Surg Res"},{"key":"2022053116192846700_ref5","first-page":"1527","article-title":"Skeletal complications of malignancy. Proceedings of a symposium. Bethesda, Maryland, April 19\u201320, 1997","volume":"80","author":"Coleman","year":"1997","journal-title":"Cancer"},{"key":"2022053116192846700_ref6","doi-asserted-by":"crossref","DOI":"10.1016\/j.bone.2020.115783","article-title":"Epidemiology of bone metastases","volume":"158","author":"Ryan","year":"2022","journal-title":"Bone"},{"key":"2022053116192846700_ref7","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1097\/MPA.0b013e318205e332","article-title":"Pancreatic carcinomas in a 60-year, institute-based autopsy material with special emphasis of metastatic pattern","volume":"40","author":"Blastik","year":"2011","journal-title":"Pancreas"},{"key":"2022053116192846700_ref8","first-page":"872","article-title":"Clinical features and management of pancreatic cancer with bone metastases","volume":"101","author":"Iguchi","year":"2004","journal-title":"Nihon Shokakibyo Gakkai Zasshi"},{"key":"2022053116192846700_ref9","first-page":"1","article-title":"Skeletal metastases in pancreatic cancer: a retrospective study and review of the literature","volume":"82","author":"Borad","year":"2009","journal-title":"Yale J Biol Med"},{"key":"2022053116192846700_ref10","doi-asserted-by":"crossref","first-page":"e43","DOI":"10.1097\/MPA.0000000000001098","article-title":"Clinical features and prognosis of patients with the bone metastasis of pancreatic cancer: a single-institutional cohort study","volume":"47","author":"Outani","year":"2018","journal-title":"Pancreas"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2022\/5\/rjac157\/43823442\/rjac157.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2022\/5\/rjac157\/43823442\/rjac157.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T17:43:47Z","timestamp":1654019027000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjac157\/6591803"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,1]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjac157","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2022,5]]},"published":{"date-parts":[[2022,5,1]]},"article-number":"rjac157"}}