{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T12:48:03Z","timestamp":1781527683174,"version":"3.54.1"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2022,5,10]],"date-time":"2022-05-10T00:00:00Z","timestamp":1652140800000},"content-version":"vor","delay-in-days":9,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Gallbladder adenocarcinoma is a rare gastrointestinal malignancy and is associated with a poor prognosis. These malignancies are most often discovered incidentally in $\\sim$1% of all cholecystectomy procedures. We report an 80-year-old male patient with iron deficiency anemia, who underwent an unremarkable endoscopy and colonoscopy, and was subsequently found to have hemobilia discovered on capsule endoscopy. Magnetic resonance cholangiopancreatography revealed a space-occupying process involving the posterior wall of the gallbladder. The patient underwent an unremarkable laparoscopic cholecystectomy with final pathology revealing a well-differentiated, 8\u00a0cm intracystic papillary neoplasm with high-grade dysplasia involving the majority of the gallbladder, with focally invasive adenocarcinoma invading the muscular layer of the gallbladder wall. Postoperative staging work-up revealed no evidence of metastatic disease. Patient then underwent a radical resection of segments 4B\/5 of the gallbladder fossa and lymph node resection of the porta hepatis. Final pathology revealed Stage I adenocarcinoma of the gallbladder (T1bNxM0).<\/jats:p>","DOI":"10.1093\/jscr\/rjac202","type":"journal-article","created":{"date-parts":[[2022,5,3]],"date-time":"2022-05-03T11:12:11Z","timestamp":1651576331000},"source":"Crossref","is-referenced-by-count":5,"title":["Gallbladder cancer presenting as hemobilia on capsule endoscopy"],"prefix":"10.1093","volume":"2022","author":[{"given":"Samantha","family":"Scarola","sequence":"first","affiliation":[{"name":"Liberty University College of Osteopathic Medicine, School of Medicine, 306 Liberty View Ln, Lynchburg, VA 24502"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Udai S","family":"Sibia","sequence":"additional","affiliation":[{"name":"Anne Arundel Medical Center at Luminis Health, Department of Surgery, 2003 Medical Parkway, Suite 301, Annapolis, 21401"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glen","family":"Gibson","sequence":"additional","affiliation":[{"name":"Anne Arundel Medical Center at Luminis Health, Department of Surgery, 2003 Medical Parkway, Suite 301, Annapolis, 21401"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,5,6]]},"reference":[{"key":"2022051023253322200_ref1","first-page":"99","article-title":"Gallbladder cancer: epidemiology and outcome","volume":"6","author":"Hundal","year":"2014","journal-title":"Clin Epidemiol"},{"key":"2022051023253322200_ref2","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1002\/cam4.1044","article-title":"Trend analysis and survival of primary gallbladder cancer in the United States: a 1973-2009 population-based study","volume":"6","author":"Rahman","year":"2017","journal-title":"Cancer Med"},{"key":"2022051023253322200_ref3","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1002\/1097-0142(19920915)70:6<1493::AID-CNCR2820700608>3.0.CO;2-U","article-title":"Carcinoma of the gallbladder. Histologic types, stage of disease, grade, and survival rates","volume":"70","author":"Henson","year":"1992","journal-title":"Cancer"},{"key":"2022051023253322200_ref4","first-page":"981","article-title":"Gallbladder carcinoma in the era of laparoscopic cholecystectomy","volume":"131","author":"Yamaguchi","year":"1996","journal-title":"Arch Surg Chic Ill 1960"},{"key":"2022051023253322200_ref5","doi-asserted-by":"crossref","first-page":"563","DOI":"10.6004\/jnccn.2017.0059","article-title":"NCCN Guidelines insights: hepatobiliary cancers, version 1.2017","volume":"15","author":"Benson","year":"2017","journal-title":"J Natl Compr Cancer Netw JNCCN"},{"key":"2022051023253322200_ref6","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.livres.2018.09.007","article-title":"Hemobilia: etiology, diagnosis, and treatment","volume":"2","author":"Berry","year":"2018","journal-title":"Liver Res"},{"key":"2022051023253322200_ref7","doi-asserted-by":"crossref","first-page":"3670739","DOI":"10.1155\/2018\/3670739","article-title":"Hemobilia: perspective and role of the advanced endoscopist","volume":"2018","author":"Berry","year":"2018","journal-title":"Gastroenterol Res Pract"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2022\/5\/rjac202\/43589480\/rjac202.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2022\/5\/rjac202\/43589480\/rjac202.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,10]],"date-time":"2022-05-10T23:25:47Z","timestamp":1652225147000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjac202\/6581743"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,1]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjac202","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,5]]},"published":{"date-parts":[[2022,5,1]]},"article-number":"rjac202"}}