{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T04:56:25Z","timestamp":1789102585460,"version":"build-2803163510"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2022,6,7]],"date-time":"2022-06-07T00:00:00Z","timestamp":1654560000000},"content-version":"vor","delay-in-days":6,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Ascites, pelvic mass and elevated CA-125 in females carry a grim prognosis, likely an ovarian carcinoma. However, more benign etiologies such as Meigs\u2019 and pseudo-Meigs\u2019 syndrome must be considered. Pseudo-Meigs\u2019 syndrome presenting with an elevated CA-125 is rare and presents a diagnostic challenge. Medline and PubMed were queried for pseudo-Meigs\u2019 syndrome cases. We present a 35-year-old female patient who presented with abdominal swelling and weight gain. Imaging demonstrated a 29-cm large intraabdominal mass with significant ascites with elevation of CA-125. Surgical resection was performed, and pathology identified uterine leiomyoma. Twenty-one cases of pseudo-Meigs\u2019 syndrome were identified in the literature. Most patients presented with abdominal distention, and some also reported dyspnea. All patients, including our case, were treated surgically. No recurrence reported among these cases. Surgery is the mainstay for radical treatment in pseudo-Meigs\u2019 syndrome. Resolution of the ascites and hydrothorax occurs following resection of the tumor.<\/jats:p>","DOI":"10.1093\/jscr\/rjac253","type":"journal-article","created":{"date-parts":[[2022,6,7]],"date-time":"2022-06-07T20:27:32Z","timestamp":1654633652000},"source":"Crossref","is-referenced-by-count":9,"title":["Large uterine leiomyoma presenting as pseudo-Meigs\u2019 syndrome with an elevated ca125: a case report and literature review"],"prefix":"10.1093","volume":"2022","author":[{"given":"Mohamed","family":"Abdelgawad","sequence":"first","affiliation":[{"name":"Department of Surgery , University of Texas Health Science Center, UT Health East Texas, Tyler, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3712-4280","authenticated-orcid":false,"given":"Lutfi","family":"Barghuthi","sequence":"additional","affiliation":[{"name":"Department of Surgery , University of Texas Health Science Center, UT Health East Texas, Tyler, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tyler","family":"Davis","sequence":"additional","affiliation":[{"name":"Department of Surgery , University of Texas Health Science Center, UT Health East Texas, Tyler, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud","family":"Omar","sequence":"additional","affiliation":[{"name":"Department of Surgery , School of Medicine, Tulane University, New Orleans, LA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar M","family":"Kamel","sequence":"additional","affiliation":[{"name":"Department of Surgery , School of Medicine, Tulane University, New Orleans, LA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jake","family":"Gibbons","sequence":"additional","affiliation":[{"name":"Department of Surgery , University of Texas Health Science Center, UT Health East Texas, Tyler, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yury","family":"Ragoza","sequence":"additional","affiliation":[{"name":"Department of Surgery , University of Texas Health Science Center, UT Health East Texas, Tyler, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hishaam","family":"Ismael","sequence":"additional","affiliation":[{"name":"Department of Surgery , University of Texas Health Science Center, UT Health East Texas, Tyler, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,6,7]]},"reference":[{"key":"2022060720272138300_ref1","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1016\/0002-9378(54)90258-6","article-title":"Fibroma of the ovary with ascites and hydrothorax; Meigs' syndrome","volume":"67","author":"Meigs","year":"1954","journal-title":"Am J Obstet Gynecol"},{"key":"2022060720272138300_ref2","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.ygyno.2004.03.045","article-title":"Pseudo-Meigs' syndrome associated with malignant struma ovarii: a case report","volume":"94","author":"Zannoni","year":"2004","journal-title":"Gynecol Oncol"},{"key":"2022060720272138300_ref3","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1186\/1752-1947-4-120","article-title":"Magnetic resonance imaging findings in pseudo-Meigs' syndrome associated with a large uterine leiomyoma: a case report","volume":"4","author":"Chourmouzi","year":"2010","journal-title":"J Med Case Reports"},{"key":"2022060720272138300_ref4","volume-title":"Radiology Review Manual","author":"Dahnert","year":"2017"},{"key":"2022060720272138300_ref5","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/S0015-0282(16)55233-9","article-title":"Massive ascites after leuprolide acetate administration for the treatment of leiomyomata uteri","volume":"58","author":"Lee","year":"1992","journal-title":"Fertil Steril"},{"key":"2022060720272138300_ref6","first-page":"609","article-title":"Leiomyoma causing massive ascites, right pleural effusion and respiratory distress. 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