{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:06:32Z","timestamp":1753877192176,"version":"3.41.2"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T00:00:00Z","timestamp":1655424000000},"content-version":"vor","delay-in-days":16,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>A 38-year-old male with sickle cell trait and acute refractory heart failure received an axillary intra-aortic balloon pump and short-term biventricular assist device. He underwent orthotopic heart transplantation 45\u00a0days later, which was complicated by major bleeding necessitating significant intra-operative transfusion. Support with veno-arterial extracorporeal membrane oxygenation was provided and successfully weaned five days later. He made a full recovery and remains alive and well 34\u00a0months after discharge. We hypothesize that the protective peri-operative measures undertaken, including normothermia during surgery and post-operative haemodynamic stability due to the use of mechanical circulatory support, conveyed a degree of protection against complications associated with sickle cell dysfunction and contributed to the successful outcome.<\/jats:p>","DOI":"10.1093\/jscr\/rjac260","type":"journal-article","created":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T23:01:31Z","timestamp":1655506891000},"source":"Crossref","is-referenced-by-count":0,"title":["Axillary intra-aortic balloon pump, biventricular assist device implantation and subsequent orthotopic heart transplantation in a patient with sickle cell trait"],"prefix":"10.1093","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5379-7090","authenticated-orcid":false,"given":"Marcus","family":"Taylor","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Transplantation, Manchester University Hospital NHS Foundation Trust , Wythenshawe Hospital, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zakariya","family":"Mouyer","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Transplantation, Manchester University Hospital NHS Foundation Trust , Wythenshawe Hospital, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Callan","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Transplantation, Manchester University Hospital NHS Foundation Trust , Wythenshawe Hospital, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steve","family":"Shaw","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Transplantation, Manchester University Hospital NHS Foundation Trust , Wythenshawe Hospital, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajamiyer","family":"Venkateswaran","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Transplantation, Manchester University Hospital NHS Foundation Trust , Wythenshawe Hospital, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nnamdi","family":"Nwaejike","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Transplantation, Manchester University Hospital NHS Foundation Trust , Wythenshawe Hospital, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,6,18]]},"reference":[{"key":"2022061723012555600_ref1","first-page":"2018","volume-title":"Sickle-Cell Disease. The Lancet","author":"Rees","year":"2010"},{"key":"2022061723012555600_ref2","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1182\/blood-2018-06-848705","article-title":"The current state of sickle cell trait: implications for reproductive and genetic counseling","volume":"132","author":"Pecker","year":"2018","journal-title":"Blood"},{"key":"2022061723012555600_ref3","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1016\/j.chest.2015.12.016","article-title":"Crises in sickle cell disease","volume":"149","author":"Novelli","year":"2016","journal-title":"Chest"},{"key":"2022061723012555600_ref4","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1093\/icvts\/ivu249","article-title":"Hypothermic cardiopulmonary bypass without exchange transfusion in sickle-cell patients: a matched-pair analysis","volume":"19","author":"Edwin","year":"2014","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"2022061723012555600_ref5","doi-asserted-by":"crossref","first-page":"2378","DOI":"10.1111\/ajt.15379","article-title":"Catastrophic sickling crisis in patient undergoing cardiac transplantation with sickle cell trait","volume":"19","author":"Ali","year":"2019","journal-title":"Am J Transplant"},{"key":"2022061723012555600_ref6","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1097\/imi.0000000000000432","article-title":"The axillary intra-aortic balloon pump as a bridge to recovery allows early ambulation in long-term use: case series and literature review","volume":"12","author":"Nwaejike","year":"2017","journal-title":"Innovations: Technol and Tech in Cardiothoracic and Vas Surg"},{"key":"2022061723012555600_ref7","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1002\/anr3.12079","article-title":"Emergency biventricular assist device implantation in a patient with suspected COVID-19 disease","volume":"8","author":"Nwaejike","year":"2020","journal-title":"Anaesthesia Reports"},{"key":"2022061723012555600_ref8","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1111\/jocs.13093","article-title":"Management of sickle cell disease in patients undergoing cardiac surgery","volume":"32","author":"Crawford","year":"2017","journal-title":"J Card Surg"},{"key":"2022061723012555600_ref9","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1111\/j.1755-5922.2009.00114.x","article-title":"Benefits and risks of maintaining normothermia during cardiopulmonary bypass in adult cardiac surgery: a systematic review","volume":"29","author":"Ho","year":"2011","journal-title":"Cardiovasc Ther"},{"key":"2022061723012555600_ref10","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1007\/s00380-015-0649-1","article-title":"Incidence, etiology, and outcome of primary graft dysfunction in adult heart transplant recipients: a single-center experience in Japan","volume":"31","author":"Seguchi","year":"2016","journal-title":"Heart Vessels"},{"key":"2022061723012555600_ref11","first-page":"58","volume-title":"Hematology Am Soc Hematol Educ Program","author":"Lottenberg","year":"2005"},{"key":"2022061723012555600_ref12","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1056\/NEJM199507273330402","article-title":"A comparison of conservative and aggressive transfusion regimens in the perioperative management of sickle cell disease","volume":"333","author":"Vichinsky","year":"1995","journal-title":"New England J Med"},{"key":"2022061723012555600_ref13","doi-asserted-by":"crossref","DOI":"10.1016\/S1010-7940(98)00198-5","article-title":"Cardiopulmonary bypass in sickle cell anaemia without exchange transfusion","volume-title":"Eur J Cardiothorac Surg.","author":"Frimpong-Boateng","year":"1998"},{"key":"2022061723012555600_ref14","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1161\/CIRCULATIONAHA.109.882464","article-title":"Open heart surgery in patients with sickle cell hemoglobinopathy","volume":"121","author":"Yousafzai","year":"2010","journal-title":"Circulation"},{"key":"2022061723012555600_ref15","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1081\/HEM-120023377","article-title":"An extreme consequence of splenectomy in dehydrated hereditary stomatocytosis: gradual thrombo-embolic pulmonary hypertension and lung-heart transplantation","volume":"27","author":"Ja\u00efs","year":"2003","journal-title":"Hemoglobin"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2022\/6\/rjac260\/44118849\/rjac260.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2022\/6\/rjac260\/44118849\/rjac260.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T23:01:44Z","timestamp":1655506904000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjac260\/6610003"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,1]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjac260","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2022,6]]},"published":{"date-parts":[[2022,6,1]]},"article-number":"rjac260"}}