{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:56:28Z","timestamp":1753876588704,"version":"3.41.2"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T00:00:00Z","timestamp":1659916800000},"content-version":"vor","delay-in-days":7,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We present the finding of a diverticulum in the colonic wall of the cecum, arising in the context of ileocecal stricture in a child with Crohn disease mimicking a post-appendectomy perforated appendiceal stump. To our knowledge, a non-Meckel diverticulum in a pediatric patient with Crohn disease has not yet been reported and we examine the mechanics behind it. According to the Laplace Law, the pressure inside a container with curved walls is inversely proportional to its radius. A diverticulum forms at the point of maximum stricture and at the locus of least resistance (weakness) in the bowel wall due to the inflammatory bowel disease. The long-time interval between diagnosis of ileocecal stricture and surgery (9\u00a0months) is important to allow the formation of this diverticulum. Continued follow-up in adulthood is warranted due to an increased risk of intestinal diverticular disease and neoplasms in patients with Crohn disease.<\/jats:p>","DOI":"10.1093\/jscr\/rjac355","type":"journal-article","created":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T20:08:42Z","timestamp":1659989322000},"source":"Crossref","is-referenced-by-count":0,"title":["Diverticular disease in a pediatric patient with Crohn\u2019s disease mimicking a perforated post-appendectomy appendiceal stump"],"prefix":"10.1093","volume":"2022","author":[{"given":"Joseph","family":"de Nanassy","sequence":"first","affiliation":[{"name":"Department of Pathology , Children\u2019s Hospital of Eastern Ontario, Ottawa, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Mack","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology , Children\u2019s Hospital of Eastern Ontario, Ottawa, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos","family":"Bettolli","sequence":"additional","affiliation":[{"name":"Department of Surgery , Children\u2019s Hospital of Eastern Ontario, Ottawa, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2779-7879","authenticated-orcid":false,"given":"Consolato M","family":"Sergi","sequence":"additional","affiliation":[{"name":"Department of Pathology , Children\u2019s Hospital of Eastern Ontario, Ottawa, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,8,5]]},"reference":[{"key":"2022080820083544900_ref1","doi-asserted-by":"crossref","first-page":"142","DOI":"10.5455\/medarh.2020.74.142-145","article-title":"Multiple small bowel diverticula were an unexpected finding during laparoscopic enterectomy for Crohn's disease","volume":"74","author":"Sotirova","year":"2020","journal-title":"Med Arch"},{"key":"2022080820083544900_ref2","first-page":"191","article-title":"Rare coexistance of Ileal diverticulosis, Crohn's disease and small bowel adenocarcinoma: report of a case","volume":"32","author":"Spartalis","year":"2018","journal-title":"In Vivo"},{"key":"2022080820083544900_ref3","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.dld.2013.04.013","article-title":"Small bowel adenocarcinoma: epidemiology, risk factors, diagnosis and treatment","volume":"46","author":"Aparicio","year":"2014","journal-title":"Dig Liver Dis"},{"key":"2022080820083544900_ref4","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-662-59169-7","volume-title":"Pathology of Childhood and Adolescence. An Illustrated Guide","author":"Sergi","year":"2020","edition":"1st"},{"key":"2022080820083544900_ref5","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1097\/MPG.0000000000001182","article-title":"Increased epithelial gap density in the noninflamed duodenum of children with inflammatory bowel diseases","volume":"63","author":"Zaidi","year":"2016","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"2022080820083544900_ref6","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1093\/ecco-jcc\/jjv223","article-title":"Mucosal barrier depletion and loss of bacterial diversity are primary abnormalities in paediatric ulcerative colitis","volume":"10","author":"Alipour","year":"2016","journal-title":"J Crohns Colitis"},{"key":"2022080820083544900_ref7","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1097\/MOG.0000000000000324","article-title":"Role of visceral fat in colonic inflammation: from Crohn's disease to diverticulitis","volume":"33","author":"Paeschke","year":"2017","journal-title":"Curr Opin Gastroenterol"},{"key":"2022080820083544900_ref8","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1136\/gut.42.3.392","article-title":"Crohn's-like reaction in diverticular disease","volume":"42","author":"Gledhill","year":"1998","journal-title":"Gut"},{"key":"2022080820083544900_ref9","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/1477-7819-5-14","article-title":"LaPlace's law revisited: cecal perforation as an unusual presentation of pancreatic carcinoma","volume":"5","author":"Slam","year":"2007","journal-title":"World J Surg Oncol"},{"key":"2022080820083544900_ref10","first-page":"21","article-title":"Morphometry of the small intestine in pigs with ileo-rectal anastomosis","volume":"61","author":"Redlich","year":"1997","journal-title":"Can J Vet Res"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2022\/8\/rjac355\/45279028\/rjac355.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2022\/8\/rjac355\/45279028\/rjac355.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T20:08:50Z","timestamp":1659989330000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjac355\/6656522"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,1]]},"references-count":10,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,8,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjac355","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2022,8,5]]},"published":{"date-parts":[[2022,8,1]]},"article-number":"rjac355"}}