{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T00:56:59Z","timestamp":1776387419384,"version":"3.51.2"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2022,8,22]],"date-time":"2022-08-22T00:00:00Z","timestamp":1661126400000},"content-version":"vor","delay-in-days":21,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Thymoma is a rare tumour that often occurs in the anterior mediastinum. Thymomas are usually diagnosed in middle-aged patients, and nearly half of cases are associated with myasthenia gravis. Thymomas typically progress through direct invasion of the thoracic cavity with extra-thoracic distant metastasis being uncommon. Here we report the case of a male patient who underwent an extensive thymectomy and radiotherapy 10\u00a0years before presentation, and in whom we detected a spleen tumour during regular out-patient follow-up. The patient underwent a splenectomy, and a final diagnosis of type B3 malignant thymoma was established.<\/jats:p>","DOI":"10.1093\/jscr\/rjac375","type":"journal-article","created":{"date-parts":[[2022,8,22]],"date-time":"2022-08-22T03:07:56Z","timestamp":1661137676000},"source":"Crossref","is-referenced-by-count":2,"title":["Spleen metastasis of recurrent malignant thymoma"],"prefix":"10.1093","volume":"2022","author":[{"given":"Chung-Wei","family":"Wu","sequence":"first","affiliation":[{"name":"Division of General Surgery , Department of Surgery, , Taipei , Taiwan"},{"name":"Shin Kong Wu Ho-Su Memorial Hospital , Department of Surgery, , Taipei , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsen-Long","family":"Yang","sequence":"additional","affiliation":[{"name":"Division of General Surgery , Department of Surgery, , Taipei , Taiwan"},{"name":"Shin Kong Wu Ho-Su Memorial Hospital , Department of Surgery, , Taipei , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,8,21]]},"reference":[{"key":"2023090619531862300_ref1","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1097\/00000421-200004000-00007","article-title":"Malignant thymoma with metastases to the gastrointestinal tract and ovary","volume":"23","author":"Bott-Kothari","year":"2000","journal-title":"Am J Clin Oncol"},{"key":"2023090619531862300_ref2","doi-asserted-by":"crossref","first-page":"2727","DOI":"10.1002\/1097-0142(19871201)60:11<2727::AID-CNCR2820601125>3.0.CO;2-D","article-title":"Thymoma. 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A case report","volume":"84","author":"Nickels","year":"1976","journal-title":"Acta Pathol Microbiol Scand A"},{"key":"2023090619531862300_ref4","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1038\/modpathol.2011.178","article-title":"Extrathoracic metastases of thymic origin: a review of 35 cases","volume":"25","author":"Tudor","year":"2012","journal-title":"Mod Pathol"},{"key":"2023090619531862300_ref5","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1080\/15384047.2016.1210738","article-title":"Isolated splenic metastasis from a thymic carcinoma: a case report","volume":"17","author":"Chen","year":"2016","journal-title":"Cancer Biol Ther"},{"key":"2023090619531862300_ref6","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/s13304-011-0124-1","article-title":"Pleuropneumonectomy for stage IVa thymoma: delayed metastatic spread after multimodality treatment","volume":"64","author":"Stella","year":"2012","journal-title":"Updates Surg"},{"key":"2023090619531862300_ref7","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1186\/s12885-018-5165-0","article-title":"Thymoma with an isolated splenic metastasis eight years after extended thymectomy: a case report","volume":"18","author":"Aoki","year":"2018","journal-title":"BMC Cancer"},{"key":"2023090619531862300_ref8","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1093\/ajcp\/111.2.235","article-title":"Immunoreactivity of a new CD5 antibody with normal epithelium and malignant tumors including thymic carcinoma","volume":"111","author":"Tateyama","year":"1999","journal-title":"Am J Clin Pathol"},{"key":"2023090619531862300_ref9","doi-asserted-by":"crossref","first-page":"24","DOI":"10.21037\/med-21-11","article-title":"Systemic treatments for thymic tumors: a narrative review","volume":"5","author":"Zucali","year":"2021","journal-title":"Mediastinum"},{"key":"2023090619531862300_ref10","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1200\/JCO.2004.10.113","article-title":"Tumor recurrence and survival in patients treated for thymomas and thymic squamous cell carcinomas: a retrospective analysis","volume":"22","author":"Str\u00f6bel","year":"2004","journal-title":"J Clin Oncol"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2022\/8\/rjac375\/51368692\/rjac375.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2022\/8\/rjac375\/51368692\/rjac375.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T19:53:30Z","timestamp":1694030010000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjac375\/6672913"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,1]]},"references-count":10,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,8,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjac375","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,8]]},"published":{"date-parts":[[2022,8,1]]},"article-number":"rjac375"}}