{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:06:46Z","timestamp":1753877206095,"version":"3.41.2"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T00:00:00Z","timestamp":1667347200000},"content-version":"vor","delay-in-days":32,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Since the beginning of the COVID-19 pandemic, there have been reports of children developing systemic hyperinflammatory response to COVID-19 infection, known as Paediatric Inflammatory Multisystem Syndrome Temporally associated with SARS-COV-2 (PIMS-TS). Here we would like to discuss a case of a 15-year-old male with PIMS-TS presenting as complicated terminal ileitis, requiring ileocaecal resection. Histopathologic findings of the ileocaecal specimen revealed thickened bowel mucosa, with features of granulomatous inflammation similar to Crohn\u2019s disease, without features of intestinal vasculitis or viral particles. His post-operative course was complicated by fresh rectal bleeding, requiring urgent blood transfusion and endoscopy. Source of bleeding was not identified and his bleeding self-resolved. Gut biopsies of the remaining bowel taken during endoscopy were normal. Although this case suggests that the inflammatory process is focal to the terminal ileum with a good short-term prognosis, further follow-up is required to assess for long-term effects and risks of bowel disease.<\/jats:p>","DOI":"10.1093\/jscr\/rjac457","type":"journal-article","created":{"date-parts":[[2022,11,4]],"date-time":"2022-11-04T05:33:25Z","timestamp":1667540005000},"source":"Crossref","is-referenced-by-count":4,"title":["A complicated case of terminal ileitis post-COVID-19 infection requiring bowel resection"],"prefix":"10.1093","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2552-3698","authenticated-orcid":false,"given":"Chai Wei","family":"Tong","sequence":"first","affiliation":[{"name":"Department of Paediatric Surgery, Sydney Children\u2019s Hospital , Randwick, New South Wales , Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashish","family":"Jiwane","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery, Sydney Children\u2019s Hospital , Randwick, New South Wales , Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,10,31]]},"reference":[{"volume-title":"Guidance: Paediatric multisystem inflammatory syndrome temporally associated with COVID-19","author":"Royal College of Paediatrics and Child Health","key":"2022110405330639200_ref1"},{"key":"2022110405330639200_ref2","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1097\/MPG.0000000000002953","article-title":"Features of intestinal disease associated with COVID-related multisystem inflammatory syndrome in children","volume":"72","author":"Sahn","year":"2021","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"2022110405330639200_ref3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.14740\/gr698w","article-title":"Facing terminal ileitis: going beyond Crohn's disease","volume":"9","author":"Goulart","year":"2016","journal-title":"Gastroenterology Res"},{"key":"2022110405330639200_ref4","doi-asserted-by":"crossref","first-page":"100075","DOI":"10.1016\/j.lanepe.2021.100075","article-title":"Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 (PIMS-TS): prospective, national surveillance, United Kingdom and Ireland, 2020","volume":"3","author":"Jessica Flood","year":"2021","journal-title":"Lancet Region Health"},{"key":"2022110405330639200_ref5","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S2352-4642(20)30304-7","article-title":"A national consensus management pathway for paediatric inflammatory multisystem syndrome temporally associated with COVID-19 (PIMS-TS): results of a national Delphi process","volume":"5","author":"Harwood","year":"2021","journal-title":"Lancet Child Adolesc Health"},{"key":"2022110405330639200_ref6","doi-asserted-by":"crossref","DOI":"10.3389\/fped.2021.667507","article-title":"Best practice recommendations for the diagnosis and management of children with pediatric inflammatory multisystem syndrome temporally associated With SARS-CoV-2 (PIMS-TS; multisystem inflammatory syndrome in children, MIS-C) in Switzerland","volume":"9","author":"Schlapbach","year":"2021","journal-title":"Front Pediatr"},{"key":"2022110405330639200_ref7","doi-asserted-by":"crossref","DOI":"10.14309\/01.ajg.0000788012.37858.49","article-title":"New diagnosis of Crohn\u2019s disease after COVID-19","volume":"116","author":"Lin","year":"2021","journal-title":"Am J Gastroenterol"},{"key":"2022110405330639200_ref8","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2020-027763","article-title":"Inflammatory bowel disease presenting with concurrent COVID-19 multisystem inflammatory syndrome","volume":"147","author":"Sweeny","year":"2021","journal-title":"Pediatrics"},{"key":"2022110405330639200_ref9","doi-asserted-by":"crossref","first-page":"e76","DOI":"10.1093\/ibd\/izab298","article-title":"COVID-19 as a trigger for de novo Crohn\u2019s disease","volume":"28","author":"Tursi","year":"2021","journal-title":"Inflamm Bowel Dis"},{"volume-title":"SECURE-IBD Database Public Data Update","author":"Brenner","key":"2022110405330639200_ref10"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2022\/10\/rjac457\/46784784\/rjac457.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2022\/10\/rjac457\/46784784\/rjac457.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,4]],"date-time":"2022-11-04T05:33:44Z","timestamp":1667540024000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjac457\/6726006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,1]]},"references-count":10,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022,10,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjac457","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2022,10]]},"published":{"date-parts":[[2022,10,1]]},"article-number":"rjac457"}}