{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T23:59:56Z","timestamp":1780444796315,"version":"3.54.1"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2022,11,13]],"date-time":"2022-11-13T00:00:00Z","timestamp":1668297600000},"content-version":"vor","delay-in-days":12,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Sarcomas are a rare heterogeneous group of neoplasms of mesenchymal origin. In the redistribution of all head and neck malignancies, sarcomas are represented by only 1%. Herein, we report a case of a 66-year-old patient with right maxillary sinus sarcoma that spread through the ostiomeatal complex, infiltrated the septum, all ethmoid cells, frontal sinus, involved the entire right nasal cavity and penetrated to the nasopharynx. Patient was treated with neoadjuvant chemotherapy, surgery and adjuvant radiotherapy. The histopathology indicated poorly differentiated sarcoma with elements of Ewing\u2019s sarcoma, but also with elements consistent with osteosarcoma. Molecular pathological analysis excluded Ewing's sarcoma. Samples were also sent for review to the other Pathology Clinics. They suggested poorly differentiated high-grade pleomorphic sarcoma with elements of osteosarcoma. The accurate diagnosis of the head and neck sarcoma type can be a histopathology dilemma posing a great challenge in the choice of therapeutic approach, and thus the treatment outcome.<\/jats:p>","DOI":"10.1093\/jscr\/rjac504","type":"journal-article","created":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T11:57:47Z","timestamp":1685015867000},"source":"Crossref","is-referenced-by-count":1,"title":["Poorly differentiated sarcoma of the maxillary sinus: a histopathology dilemma of a rare tumor"],"prefix":"10.1093","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6988-5896","authenticated-orcid":false,"given":"Tena","family":"\u0160imunjak","sequence":"first","affiliation":[{"name":"University Hospital Sveti Duh Department of Otorhinolaryngology, Head and Neck Surgery, , Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boris","family":"\u0160imunjak","sequence":"additional","affiliation":[{"name":"University Hospital Sveti Duh Department of Otorhinolaryngology, Head and Neck Surgery, , Zagreb, Croatia"},{"name":"Josip Juraj Strossmayer University of Osijek Faculty of Dental Medicine and Health Osijek, , Osijek, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Jurlina","sequence":"additional","affiliation":[{"name":"University Hospital Dubrava Department of Maxillofacial Surgery, , Zagreb, Croatia"},{"name":"University of Zagreb , School of Medicine, Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matea","family":"Zrno","sequence":"additional","affiliation":[{"name":"University Hospital Sveti Duh Department of Otorhinolaryngology, Head and Neck Surgery, , Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,11,14]]},"reference":[{"key":"2023052511390846100_ref1","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.coms.2017.04.002","article-title":"Margin analysis: sarcoma of the head and neck","volume":"29","author":"Makary","year":"2017","journal-title":"Oral Maxillofac Surg Clin North Am"},{"key":"2023052511390846100_ref2","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.suc.2008.03.006","article-title":"Sarcoma epidemiology and etiology: potential environmental and genetic factors","volume":"88","author":"Lahat","year":"2008","journal-title":"Surg Clin North Am"},{"key":"2023052511390846100_ref3","doi-asserted-by":"crossref","first-page":"e138","DOI":"10.1055\/s-0040-1701221","article-title":"Sinonasal osteosarcoma: report of 14 new cases and systematic review of the 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