{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:06:50Z","timestamp":1753877210585,"version":"3.41.2"},"reference-count":6,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2022,11,27]],"date-time":"2022-11-27T00:00:00Z","timestamp":1669507200000},"content-version":"vor","delay-in-days":26,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Antineutrophil cytoplasmic antibody (ANCA) associated vasculitis encompasses a group of rare multi-system affecting diseases that can present with unremitting cases of common conditions. We present a case of a middle-aged gentleman admitted under Urology with epidymo-orchitits on multiple occasions. Ultrasound revealed segmental testicular infarcts, and he was managed conservatively. He re-presented shortly after discharge to the medical assessment unit with ulnar nerve paraesthesia, thought to be due to ulnar nerve entrapment syndrome. Less than 1\u00a0week later he was re-admitted again, with severe peripheral nerve pain in all limbs and multifocal weakness. Initial history and examination gave a provisional diagnosis of mononeuritis multiplex. Following investigations and treatment, this was deemed to be caused by a converging diagnosis of C-ANCA PR3 positive vasculitis, a small vessel vasculitis. This case highlights that patients with unremitting cases of epididymo-orchitis with testicular infarcts may benefit from autoimmune screening.<\/jats:p>","DOI":"10.1093\/jscr\/rjac548","type":"journal-article","created":{"date-parts":[[2022,11,27]],"date-time":"2022-11-27T22:19:23Z","timestamp":1669587563000},"source":"Crossref","is-referenced-by-count":0,"title":["Antineutrophil cytoplasmic antibody associated vasculitis: a converging diagnosis from neuropathy and testicular infarcts"],"prefix":"10.1093","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3641-4382","authenticated-orcid":false,"given":"Ross","family":"Mercer","sequence":"first","affiliation":[{"name":"School of Anatomy, University of Bristol , Bristol , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angus","family":"White","sequence":"additional","affiliation":[{"name":"Department of Urology, Aneurin Bevan University Health Board , Newport , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Bates","sequence":"additional","affiliation":[{"name":"Department of Urology, Aneurin Bevan University Health Board , Newport , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,11,26]]},"reference":[{"key":"2022112722191523000_ref1","doi-asserted-by":"crossref","first-page":"1656","DOI":"10.1093\/rheumatology\/kew232","article-title":"Incidence of ANCA-associated vasculitis in a UK mixed ethnicity population","volume":"55","author":"Pearce","year":"2016","journal-title":"Rheumatol Oxf Engl"},{"key":"2022112722191523000_ref2","doi-asserted-by":"crossref","first-page":"e5096","DOI":"10.1097\/MD.0000000000005096","article-title":"Diagnosing ANCA-associated vasculitis in ANCA positive patients: a retrospective analysis on the role of clinical symptoms and the ANCA titre","volume":"95","author":"Houben","year":"2016","journal-title":"Medicine (Baltimore)"},{"key":"2022112722191523000_ref3","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1093\/rheumatology\/kex261","article-title":"Clinical characteristics of inflammatory ocular disease in anti-neutrophil cytoplasmic antibody associated vasculitis: a retrospective cohort study","volume":"56","author":"Ungprasert","year":"2017","journal-title":"Rheumatol Oxf Engl"},{"key":"2022112722191523000_ref4","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/j.urology.2011.01.021","article-title":"Testicular vasculitis: a series of 19 cases","volume":"77","author":"Brimo","year":"2011","journal-title":"Urology"},{"key":"2022112722191523000_ref5","article-title":"Segmental testicular infarction secondary to testicular vasculitis: a case report & Literature Review","author":"Teh","year":"2019","journal-title":"The Royal Australian and New Zealand College of Radiologists"},{"volume-title":"Scenario: Epididymo-orchitis | Management | Scrotal pain and swelling","key":"2022112722191523000_ref6"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2022\/11\/rjac548\/47306921\/rjac548.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2022\/11\/rjac548\/47306921\/rjac548.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,27]],"date-time":"2022-11-27T22:19:27Z","timestamp":1669587567000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjac548\/6847496"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,1]]},"references-count":6,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2022,11,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjac548","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2022,11]]},"published":{"date-parts":[[2022,11,1]]},"article-number":"rjac548"}}