{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T04:34:06Z","timestamp":1770957246961,"version":"3.50.1"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2023,3,17]],"date-time":"2023-03-17T00:00:00Z","timestamp":1679011200000},"content-version":"vor","delay-in-days":16,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Cystic fibrosis (CF) is commonly associated with gastrointestinal manifestations from infancy to adulthood. Distal intestinal obstruction syndrome (DIOS) affects 20% of CF patients, where intussusception can be a rare complication. A 20-year-old CF male was diagnosed with a 3-day history of right iliac fossa pain and diarrhoea. Clinical examination revealed a tender palpable mass in the right iliac fossa and raised serum inflammatory markers. Contrast computerized-tomography of the abdomen-pelvis suggested intussusception of the appendix and further confirmed on histological analyses. The patient underwent an open appendicectomy where the intussusception had self-resolved. The literature review indicated a scarcity of data with 10 cases reported of intussusception in adult CF patients. Our case was in line with previous research of transient intussusception. This rare case highlights an importance to carry a higher index of suspicion for gastrointestinal manifestations in CF patients where differential diagnoses of DIOS and intussusception should be considered in the acute presentation.<\/jats:p>","DOI":"10.1093\/jscr\/rjad117","type":"journal-article","created":{"date-parts":[[2023,3,17]],"date-time":"2023-03-17T23:39:20Z","timestamp":1679096360000},"source":"Crossref","is-referenced-by-count":3,"title":["Intussusception of the appendix in a young adult: an important differential diagnosis of abdominal pain in cystic fibrosis patients?"],"prefix":"10.1093","volume":"2023","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3055-1295","authenticated-orcid":false,"given":"Meena","family":"Venkatasami","sequence":"first","affiliation":[{"name":"Department of Pathology, Royal Shrewsbury Hospital , Shrewsbury SY3 8XQ , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ellen","family":"Cobby","sequence":"additional","affiliation":[{"name":"Department of Pathology, Royal Shrewsbury Hospital , Shrewsbury SY3 8XQ , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,3,17]]},"reference":[{"key":"2023031723391055000_","doi-asserted-by":"crossref","first-page":"S24","DOI":"10.1016\/S1569-1993(11)60005-2","article-title":"Guidelines for the diagnosis and management of distal intestinal obstruction syndrome in cystic fibrosis patients","volume":"10","author":"Colombo","year":"2011","journal-title":"J Cyst Fibros"},{"key":"2023031723391055000_","doi-asserted-by":"crossref","first-page":"38","DOI":"10.12968\/hmed.2017.78.1.38","article-title":"Distal intestinal obstruction syndrome and colonic pathologies in cystic fibrosis","volume":"78","author":"Canny","year":"2017","journal-title":"Br J Hosp 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