{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:06:01Z","timestamp":1753877161809,"version":"3.41.2"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2023,3,25]],"date-time":"2023-03-25T00:00:00Z","timestamp":1679702400000},"content-version":"vor","delay-in-days":24,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Scrotal squamous cell carcinoma (SCC) is a rare condition that typically manifests in the sixth decade of life and usually presents as a painless, solitary nodule that slowly increases in size, ulcerates, and gets infected. The diagnosis is often delayed, as the majority of patients tend to avoid seeking medical help due to embarrassment. We present a 62-year-old male with a massive 8\u00a0cm ulcerating painless tumor in the scrotum. A patient underwent scrotal extirpation with bilateral orchofuniculectomy and diagnostic bilateral inguinal lymphadenectomy. Histopathology revealed a well-differentiated SCC of the scrotal skin. Ignorance, lack of self-awareness, knowledge about risk factors and aggravated access to healthcare facilities remain important reasons for late diagnosis.<\/jats:p>","DOI":"10.1093\/jscr\/rjad128","type":"journal-article","created":{"date-parts":[[2023,3,25]],"date-time":"2023-03-25T16:56:43Z","timestamp":1679763403000},"source":"Crossref","is-referenced-by-count":3,"title":["Scrotal squamous cell carcinoma: a case report"],"prefix":"10.1093","volume":"2023","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6268-0326","authenticated-orcid":false,"given":"Giedr\u0117","family":"\u017dulpait\u0117","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Vilnius University , 03101 Vilnius , Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R\u016bta","family":"\u017dulpait\u0117","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Vilnius University , 03101 Vilnius , Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alvydas","family":"V\u0117\u017eelis","sequence":"additional","affiliation":[{"name":"National Cancer Institute , 08660 Vilnius , Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,3,25]]},"reference":[{"key":"2023032516563394300_","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.clindermatol.2013.01.003","article-title":"Anogenital malignancies and premalignancies: facts and controversies","volume":"31","author":"Kutlubay","year":"2013","journal-title":"Clin Dermatol"},{"key":"2023032516563394300_","doi-asserted-by":"crossref","first-page":"68","DOI":"10.33590\/emjurol\/10314467","article-title":"A systematic review of scrotal squamous cell carcinoma","volume":"7","author":"Sarkar","year":"2019","journal-title":"EMJ Urol Urol 71"},{"key":"2023032516563394300_","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1038\/sj.bjc.6605914","article-title":"Scrotal cancer: incidence, survival and second primary tumours in the Netherlands since 1989","volume":"103","author":"Verhoeven","year":"2010","journal-title":"Br J Cancer"},{"key":"2023032516563394300_","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.ucl.2016.06.013","article-title":"Preneoplastic and primary scrotal cancer: updates on pathogenesis and diagnostic evaluation","volume":"43","author":"Zhu","year":"2016","journal-title":"Urol Clin North Am"},{"key":"2023032516563394300_","article-title":"A review of the history, epidemiology and treatment of squamous cell carcinoma of the scrotum","volume":"1","author":"Azike","year":"2009","journal-title":"Rare Tumors"},{"key":"2023032516563394300_","article-title":"Scrotal cutaneous metastasis from rectal squamous cell carcinoma: a rare evolution into a rare tumor","volume":"43","year":"2021","journal-title":"Exp Oncol"},{"key":"2023032516563394300_","doi-asserted-by":"crossref","first-page":"bcr-2018\u2013226053","DOI":"10.1136\/bcr-2018-226053","article-title":"Squamous cell carcinoma of scrotum mimicking as scrotal abscess","volume":"2018","author":"Garg","year":"2018","journal-title":"BMJ Case Rep"},{"key":"2023032516563394300_","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/S0022-5347(17)58608-5","article-title":"Experience with carcinoma of the scrotum","volume":"117","author":"Ray","year":"1977","journal-title":"J Urol"},{"key":"2023032516563394300_","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/0090-4295(82)90497-6","article-title":"Carcinoma of scrotum","volume":"19","author":"McDonald","year":"1982","journal-title":"Urology"},{"key":"2023032516563394300_","doi-asserted-by":"crossref","first-page":"150","DOI":"10.4103\/0019-5278.146916","article-title":"Squamous cell carcinoma of the scrotum - still an occupational hazard","volume":"18","author":"Mitra","year":"2014","journal-title":"Indian J Occup Environ Med"},{"key":"2023032516563394300_","first-page":"1630","volume-title":"Campbell-Walsh Urology","author":"Chung","year":"2015","edition":"10th"},{"key":"2023032516563394300_","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/0090-4295(86)90408-5","article-title":"Lasers and squamous cell carcinoma of external genitalia","volume":"27","author":"Rosemberg","year":"1986","journal-title":"Urology"},{"key":"2023032516563394300_","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1054\/bjps.2002.3868","article-title":"Squamous cell carcinoma of the penile skin in a neovagina 20 years after male-to-female reassignment","volume":"55","author":"Harder","year":"2002","journal-title":"Br J Plast Surg"},{"key":"2023032516563394300_","first-page":"683","article-title":"A case of scrotal cancer with inguinal lymph node metastasis treated by multidisciplinary modalities including chemotherapy with methotrexate, bleomycin and cisplatin","volume":"43","author":"Arai","year":"1997","journal-title":"Hinyokika Kiyo"},{"key":"2023032516563394300_","first-page":"455","article-title":"Primary carcinomas of the scrotum\u20135 cases","volume":"80","author":"Poly\u00e1k","year":"1987","journal-title":"Z Urol Nephrol"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2023\/3\/rjad128\/49630300\/rjad128.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2023\/3\/rjad128\/49630300\/rjad128.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,7]],"date-time":"2023-12-07T17:47:13Z","timestamp":1701971233000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjad128\/7085846"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,1]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjad128","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2023,3]]},"published":{"date-parts":[[2023,3,1]]},"article-number":"rjad128"}}